Results 11 to 20 of about 175,835 (341)

Nano-Encapsulated Melatonin: A Promising Mucosal Adjuvant in Intranasal Immunization against Chronic Experimental T. gondii Infection

open access: yesTropical Medicine and Infectious Disease, 2022
Melatonin (MLT) is now emerging as one of the universally accepted immunostimulators with broad applications in medicine. It is a biological manipulator of the immune system, including mucosal ones. MLT was encapsulated in solid lipid nanoparticles (SLNs)
Doaa E. Said   +5 more
doaj   +1 more source

Intranasal delivery of a chimpanzee adenovirus vector expressing a pre-fusion spike (BV-AdCoV-1) protects golden Syrian hamsters against SARS-CoV-2 infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
We evaluated the immunogenicity and protective ability of a chimpanzee replication-deficient adenovirus vectored COVID-19 vaccine (BV-AdCoV-1) expressing a stabilized pre-fusion SARS-CoV-2 spike glycoprotein in golden Syrian hamsters.
Shen Wang   +20 more
doaj   +1 more source

Using intranasal corticosteroids [PDF]

open access: yesCanadian Medical Association Journal, 2021
About 5% of Canadians are affected by sinonasal inflammation.[1][1] There is broad expert consensus supporting the effectiveness of intranasal corticosteroids for treating allergic and nonallergic rhinitis, acute rhinosinusitis and chronic rhinosinusitis with and without nasal polyposis.[2][2],[3 ...
Fowler, James, Sowerby, Leigh J
openaire   +2 more sources

Comparison of intranasal midazolam versus intranasal ketamine for preoperative anesthetic sedation in pediatric patients

open access: yesThe Indian Anaesthetists' Forum, 2020
Introduction: During induction of anesthesia anxiety of children may be reduced more effectively by sedative medication than parental presence. Keeping in view, the necessity of reducing preoperative anxiety and postoperative psychological problem in ...
Nandini Chouhan   +3 more
doaj   +1 more source

A Compensatory Liability Regime to Promote the Exchange of Microbial Genetic Resources for Research and Benefit Sharing [PDF]

open access: yes, 2011
Female rhesus macaques were immunized with HIV virus-like particles (HIV-VLPs) or HIV DNA administered as sequential combinations of mucosal (intranasal) and systemic (intramuscular) routes, according to homologous or heterologous prime-boost schedules ...
Andersen, Hanne   +10 more
core   +2 more sources

Intranasal esketamine as therapeutic option: a case report of an adolescent with treatment resistant depression

open access: yesFrontiers in Psychiatry, 2023
Depression is among the most common mental health disorders worldwide and treatment resistant depression (TRD) represents a major challenge for both patients and clinicians.
Katrin Skala   +6 more
doaj   +1 more source

Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats [PDF]

open access: yes, 2003
The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Couet, William   +5 more
core   +3 more sources

Case report: Intramuscular ketamine or intranasal esketamine as a treatment in four patients with major depressive disorder and comorbid anorexia nervosa

open access: yesFrontiers in Psychiatry, 2023
IntroductionA comorbid diagnosis of a depressive disorder is a negative prognostic factor for individuals with AN, and novel treatments are needed to target depressive symptoms in this population. One emerging promising treatment for depressive disorders
Johanna Louise Keeler   +9 more
doaj   +1 more source

Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment

open access: yesPharmaceuticals, 2022
A liposphere system for intranasal delivery of quetiapine fumarate (QTF) was created to assess the potential for enhanced drug delivery. We investigated the effects of particle size, entrapment effectiveness, poly dispersibility index, and pluronic ...
Randa Mohammed Zaki   +8 more
doaj   +1 more source

Inhaled Insulin: Intrapulmonary or Intranasal? [PDF]

open access: yes, 2012
Initial attempts delivered the insulin hormone intramuscularly, intravenously, and eventually subcutaneously. Other routes of administration of the drug were explored.
Danish Ahmed   +3 more
core   +2 more sources

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