Allergy, EarlyView.This study aimed to evaluate the feasibility of extending dupilumab dosing intervals in T2‐CRSwNP by assessing how many patients maintain disease control with once‐every‐12‐weeks (Q12W) dosing and comparing clinical characteristics of super‐responders and excellent responders. Tapering of dupilumab to Q12W appears feasible in super‐responding patients.
P. E. Vonk +13 more
wiley +1 more source
Corrigendum to "Intranasal esketamine in treatment-resistant depression: long-term dosing patterns and clinical outcomes in a 5-year observational study". [PDF]
Ther Adv Psychopharmacoleuropepmc +1 more source
Multi-Antigen Protein Vaccine Confers Protection in a Murine Model Against Intranasal <i>Haemophilus influenzae</i> Challenge. [PDF]
Vaccines (Basel)Belkacem N, Deghmane AE, Taha MK.
europepmc +1 more source
Allergy, EarlyView.This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake +8 more
wiley +1 more source
Efficacy and Adherence of Combined Fluticasone Propionate and Azelastine Nasal Spray Versus Fluticasone Propionate Alone in Pediatric Allergic Rhinitis. [PDF]
Allergy Asthma Immunol ResÇelik FÇ +7 more
europepmc +1 more source
Comparative efficacy and post-discharge adverse events of intranasal dexmedetomidine combined with different oral medications for procedural sedation in children: a randomized controlled trial. [PDF]
Front PharmacolLi H, Zhou D, Du M, Xu Y.
europepmc +1 more source
Allergy, EarlyView.This randomized, double‐blind, placebo‐controlled trial evaluated the effects of live probiotic and HT postbiotic B. longum CECT 7347 in adults with moderate–severe allergic rhinitis. Postbiotic supplementation for 8 weeks significantly reduced CSMS and dSS, exceeding the established CSMS MCID with a 33% greater improvement, when compared to placebo ...
Ana Cardoso +9 more
wiley +1 more source
Toward Integrating Intranasal Esketamine with Traumatic-Memory Psychotherapy in Treatment-Resistant Depression: A Narrative Review and Feasibility-Oriented Protocol Proposal. [PDF]
Behav Sci (Basel)Raffone F +4 more
europepmc +1 more source
Allergy, EarlyView.ABSTRACT Background To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.
Bernardo Sousa‐Pinto +44 more
wiley +1 more source
Advances in the management of allergic rhinitis: clinical relevance of the mometasone furoate-olopatadine association and the challenge of patient self-diagnosis and self-treatment. [PDF]
Drugs ContextD'Amato M, D'Amato G.
europepmc +1 more source