Results 191 to 200 of about 119,783 (316)

Chronic High‐Dose Ketamine Fails to Induce a Cystitis‐Like Phenotype in Mice Despite High Urinary Metabolite Levels

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims Ketamine‑induced cystitis (KIC) is a severe complication of chronic ketamine misuse, yet the underlying mechanisms remain poorly understood. Established rodent models have demonstrated variable changes in voiding behavior and bladder histology, without exploring the sensory mechanisms underlying altered voiding and pain at all. This study
Jill Dewez   +11 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

Clinic‐Based Transnasal Marsupialization for the Treatment of Congenital Dacryocystocele

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the feasibility and outcomes of endoscopic intranasal marsupialization as treatment for congenital dacryocystocele, performed under topical anesthesia in a clinical setting. Study Design A retrospective review was conducted at a tertiary pediatric care hospital spanning from 2014 to 2024.
Camille Caron   +4 more
wiley   +1 more source

Modelling Olfactory Dysfunction in Rodents Through Intranasal Vanadium Exposure. [PDF]

open access: yesAnimals (Basel)
Pereira M   +4 more
europepmc   +1 more source

Efficacy of Exhalation Delivery System With Fluticasone in Chronic Rhinosinusitis With Versus Without Polyps

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate whether treatment responses to the exhalation delivery system with fluticasone (EDS‐FLU; XHANCE®) differ between patients with CRS with nasal polyps (CRSwNP) and patients without nasal polyps (CRSsNP). Study Design Post hoc analysis of the ReOpen clinical trials conducted between November 2018 and November 2021 for a 24 ...
Rodney J. Schlosser   +12 more
wiley   +1 more source

Association of Nasal Anatomy, Airflow, and Surgery With Olfactory Outcomes: A State‐of‐the‐Art Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Olfactory function is influenced by nasal airflow dynamics and anatomical variations within the nasal cavity. This narrative review evaluates how nasal anatomy and airflow relate to olfactory outcomes, with a particular focus on olfactory changes following functional nasal surgery. Data Sources PubMed.
Joshua Ferreira   +3 more
wiley   +1 more source

Clinical Management and Outcomes of Neonatal Rhinitis Nasal Obstruction: A Scoping Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Neonatal rhinitis represents an underdiagnosed yet potentially serious condition in newborns. Standardized diagnostic and treatment protocols remain lacking. The objective is to review the current literature on the etiology, diagnosis, and management of neonatal rhinitis in infants ≤8 months of age.
Anthony Victor, Mathieu Bergeron
wiley   +1 more source

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