Results 191 to 200 of about 107,310 (319)

Mucosal Vaccine Development: From Adjuvant Design to Next-Generation Delivery Strategies. [PDF]

Biomedicines
Lee WH, Kim E.
europepmc   +1 more source

Enhanced Early Detection of Allergic Rhinitis: A Prospective Study on a Symptom‐Based Predictive Model

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Allergic rhinitis (AR) and non‐allergic rhinitis (NAR) share overlapping symptoms but differ in pathophysiology and treatment. Current AR diagnosis relies on skin prick testing (SPT) and serum IgE quantification, both of which are complex.
Ke‐Zhang Zhu, Chao He, Si‐Zhe Zhu, Zheng Liu, Ming Zeng   +4 more
wiley   +1 more source

The Efficacy and Safety of Intranasal Dexmedetomidine Spray Followed by Nitrous Oxide for Paediatric Oral Procedures. [PDF]

Int Dent J
Xiao YJ, Zhang HY, Nie MD, Liu GS, Peng W, Zhao JH, Hu ZH, Sun H, Wu Y.   +8 more
europepmc   +1 more source

Targeting Inflammatory Alarmin S100A9 Modulates Activation of Pro‐Inflammatory Macrophage to Protect Nasal Epithelial Cells From LPS‐Induced Epithelial–Mesenchymal Transition

Microbiology and Immunology, EarlyView.
ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) exhibits pronounced endotypic heterogeneity, with macrophages serving as key drivers of sustained mucosal inflammation. In this study, we identify S100A9 as a macrophage‐derived alarmin that is markedly elevated in CRSwNP tissues.
Yunxiang Ji, Jia Luan, Fang Yuan, Zhao Wang, Ran Wei, Guangbin Sun   +5 more
wiley   +1 more source

Oxytocin attenuates fear learning via enhancing somatostatin interneuron-mediated local GABAergic inhibition in the prelimbic cortex. [PDF]

Sci Adv
Xu H, Li Y, Cui X, Zhang Y, Wu X, Zhuo SS, He M, Xiao L.   +7 more
europepmc   +1 more source

Hormone Replacement Therapy Uptake and Discontinuation Trends From 1996‐2023: An Observational Study of the Welsh Population

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To analyse prescribing trends for oral and transdermal hormone replacement therapy (HRT) in Wales from 1996 to 2023, including predictors of discontinuation within one year of initiation. Design Observational study using the Secure Anonymised Information Linkage (SAIL) databank.
Robin Andrews, Arron Lacey, Kate Bache, Emma J. Kidd   +3 more
wiley   +1 more source

Neurofunctional and Clinical Effects of Intranasal Human Recombinant Nerve Growth Factor in Children with Acquired Brain Injury. [PDF]

Pharmaceuticals (Basel)
Di Sarno L, Ferretti S, Capossela L, Gatto A, Pansini V, Manni L, Chiaretti A.   +6 more
europepmc   +1 more source

Intranasal Zinc Ionization [PDF]

BMJ, 1937
L D, Bailey, C, Shields
openaire   +2 more sources

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Fluticasone Furoate-Oxymetazoline Hydrochloride Combination Nasal Spray for Managing Allergic Rhinitis With Nasal Congestion: Current Evidence and Clinical Implications. [PDF]

Cureus
Verma S, Meghanadh KR, Lal S, Kotamkar A, Pallewar S, Qamra A.   +5 more
europepmc   +1 more source