Results 171 to 180 of about 119,783 (316)

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng   +8 more
wiley   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen   +9 more
wiley   +1 more source

Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system

open access: yes, 2016
Jeremy WD McGowan,1 Qingmei Shao,1 Parminder JS Vig,1,2 Gene L Bidwell III1,2 1Department of Neurology, 2Department of Biochemistry, University of Mississippi Medical Center, Jackson, MS, USA Abstract: Bypassing the blood–brain barrier is one of ...
Vig PJS   +3 more
core  

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu   +2 more
wiley   +1 more source

Human Factors and Device Engineering in OTC Intranasal Drug Delivery: GentleMist Technology™. [PDF]

open access: yesPharmaceutics
Alas-Pineda C   +6 more
europepmc   +1 more source

Superior Labial Artery Flap for Septal Perforation Repair: The Boxer's Flap

open access: yesThe Laryngoscope, EarlyView.
The nasal floor flap, or Boxer's flap, is an anteriorly pedicled, superior labial artery–based mucosal flap that provides excellent closure rates in septal perforation repair when traditional septal flaps are not feasible. The schematic shows: (A) preoperative perforation, (B) nasal floor flap elevation (with the pedicle maintained at the inferior ...
Nicholas J. Campion   +5 more
wiley   +1 more source

Effects of intranasal insulin on central nervous system redox homeostasis

open access: yes
Razumijevanje načina na koji intranazalna primjena inzulina utječe na signalizaciju i metabolizam mozga ključno je za razjašnjavanje njegovog terapijskog potencijala kod neurodegenerativnih poremećaja povezanih s metaboličkom disfunkcijom, poput ...
Vlahov, Leonarda
core  

Radiofrequency Neurolysis of the Posterior Nasal Nerve: A Systematic Review and Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
Radiofrequency neurolysis of the posterior nasal nerve significantly improves symptoms of chronic rhinitis, including nasal obstruction and rhinorrhea, while demonstrating a favorable safety profile. This systematic review and meta‐analysis supports the procedure as an effective minimally invasive treatment, although additional high‐quality randomized ...
Eyad Jamileh   +5 more
wiley   +1 more source

How I Do It: Nasoseptal Flap for Reconstruction of Isolated Soft Palate Defect

open access: yesThe Laryngoscope, EarlyView.
A vascularized nasoseptal flap (NSF) provides a novel transnasal option for repairing soft palatal fistulas when traditional transoral flaps have failed or are unavailable, potentially avoiding the morbidity of regional or free tissue transfer. In the current patient who had an 8 × 6 mm soft palatal fistula, the NSF was harvested from the septum and ...
Vincent M. Desiato   +3 more
wiley   +1 more source

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