Results 21 to 30 of about 175,835 (341)

Ameliorating Impact of Prophylactic Intranasal Oxytocin on Signs of Fear in a Rat Model of Traumatic Stress

Frontiers in Behavioral Neuroscience, 2018
Oxytocin treatment reduces signs of long-term emotional stress after exposure to trauma; however, little is known about the potential protective effects of oxytocin treatment on behavioral and physiological changes associated with extreme stress exposure.
Micah D. Renicker, Nicholas Cysewski, Samuel Palmer, Dmytro Nakonechnyy, Andrew Keef, Morgan Thomas, Krisztian Magori, David P. Daberkow   +7 more
doaj   +1 more source

Intranasal Delivery: Effects on the Neuroimmune Axes and Treatment of Neuroinflammation

Pharmaceutics, 2020
This review highlights the pre-clinical and clinical work performed to use intranasal delivery of various compounds from growth factors to stem cells to reduce neuroimmune interactions.
Elizabeth M. Rhea, Aric F. Logsdon, William A. Banks, Michelle E. Erickson   +3 more
doaj   +1 more source

RETRACTED: QbD-based rivastigmine tartrate-loaded solid lipid nanoparticles for enhanced intranasal delivery to the brain for Alzheimer's therapeutics

Frontiers in Aging Neuroscience, 2022
Alzheimer's disease (AD) is a neurodegenerative disease that affects a wide range of populations and is the primary cause of death in various countries.
Deepshi Arora, Deepshi Arora, Shailendra Bhatt, Manish Kumar, Ravinder Verma, Yugam Taneja, Nikita Kaushal, Abhishek Tiwari, Varsha Tiwari, Athanasios Alexiou, Athanasios Alexiou, Sarah Albogami, Saqer S. Alotaibi, Vineet Mittal, Rajeev K. Singla, Rajeev K. Singla, Deepak Kaushik, Gaber El-Saber Batiha   +17 more
doaj   +1 more source

Seasonal patterns of oral antihistamine and intranasal corticosteroid purchases from Australian community pharmacies : a retrospective observational study [PDF]

, 2017
Acknowledgments The abstract of this paper was presented at the Respiratory Effectiveness Group 2016 Annual Summit as a poster presentation with interim findings.
Bosnic-Anticevich, Sinthia Z, Carney, A. Simon, Carter, Victoria, Christian, Louise, Durieux, Alice M. S., Harvey, Richard, Kritikos, Vicky, Price, David B., Skinner, Derek A., Smith, Pete K.   +9 more
core   +3 more sources

Innovative Aqueous Nanoemulsion Prepared by Phase Inversion Emulsification with Exceptional Homogeneity

Pharmaceutics, 2023
Formulating low-solubility or low-permeability drugs is a challenge, particularly with the low administration volumes required in intranasal drug delivery.
Patrícia C. Pires, Mariana Fernandes, Francisca Nina, Francisco Gama, Maria F. Gomes, Lina E. Rodrigues, Sara Meirinho, Samuel Silvestre, Gilberto Alves, Adriana O. Santos   +9 more
doaj   +1 more source

Oxytocin and social pretreatment have similar effects on processing of negative emotional faces in healthy adult males [PDF]

, 2013
Oxytocin has been shown to affect several aspects of human social cognition, including facial emotion processing. There is also evidence that social stimuli (such as eye-contact) can effectively modulate endogenous oxytocin levels.
Hernádi, Anna, Kemerle, Kinga, Topál, József, Vargáné Kis, Anna   +3 more
core   +1 more source

Formulation of Intranasal Mucoadhesive Thermotriggered In Situ Gel Containing Mirtazapine as an Antidepressant Drug

Gels, 2023
The purpose of the present work was to develop nanoemulsion-based formulations of mirtazapine for intranasal delivery using a spray actuator to target the brain for treating depression.
Mohammed Ghazwani, Rajalakshimi Vasudevan, Geetha Kandasamy, Naredla. Manusri, Praveen Devanandan, Ranadheer Chowdary Puvvada, Vinoth Prabhu Veeramani, Premalatha Paulsamy, Krishnaraju Venkatesan, Kumarappan Chidmabaram, Rajeshri Dhurke   +10 more
doaj   +1 more source

An Elucidation of Contemporary Brain Targeting Tactics Employed in the Treatment of Neurodegenerative Diseases

Archives of Pharmaceutical Sciences Ain Shams University, 2023
Neurodegenerative diseases (NDDs), a global growing concern, are posing significant social and economic challenges, making the efficient delivery of medications to the brain a pressing demand.
Authman M. Alsamarrai, Ghada M. El Zaafarany, Amany O. Kamel   +2 more
doaj   +1 more source

Comparing the immune response to a novel intranasal nanoparticle PLGA vaccine and a commercial BPI3V vaccine in dairy calves [PDF]

, 2015
peer-reviewedBackground There is a need to improve vaccination against respiratory pathogens in calves by stimulation of local immunity at the site of pathogen entry at an early stage in life. Ideally such a vaccine preparation would not be inhibited by
A Menanteau-Horta, A Vila, AR Peters, B Morein, B Morein, Bernadette Earley, BJF Bradshaw, BM Adair, Bryan Markey, C Pilette, CA Siegrist, CX Song, DG Bryson, DP Greenberg, EM Liebler-Tenorio, F Alexis, F Mansoor, Fawad Mansoor, FM Buonaguro, HM Chen, I Vangeel, J Phillips, J Pollock, JE Crowe, Joseph P. Cassidy, JS Salt, K Tahara, KJ Wiechelman, M Garinot, M Higaki, Michael D. Welsh, ML Hans, MS Lee, OV Kavanagh, PE Shewen, PK Smith, PR Wood, RE Brown, RM Zinkernagel, S Lofthouse, Simon Doherty, TG Kimman, YJ Kwon   +42 more
core   +1 more source

An Improved Tobacco Mosaic Virus (TMV)-Conjugated Multiantigen Subunit Vaccine Against Respiratory Tularemia

Frontiers in Microbiology, 2018
Francisella tularensis, the causative agent of the fatal human disease known as tularemia is classified as a Category A Select Agent by the Centers for Disease Control.
Ahd A. Mansour, Sukalyani Banik, Ragavan V. Suresh, Hardeep Kaur, Meenakshi Malik, Alison A. McCormick, Chandra S. Bakshi   +6 more
doaj   +1 more source