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Intranasal Naloxone Administration
New England Journal of Medicine, 2021Intranasal Administration of Naloxone Intranasal naloxone is used to treat patients with respiratory and central nervous system depression that is known or suspected to be caused by an opioid overd...
Rafael Ortega +4 more
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ACS Nano, 2022
The treatment of Parkinson's disease (PD) has been hindered by the complex pathologies and multiple membrane barriers during drug delivery. Although exosomes derived from mesenchymal stem cells (MSCs) have great potential for PD, MSC-derived exosomes ...
Huan Peng +12 more
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The treatment of Parkinson's disease (PD) has been hindered by the complex pathologies and multiple membrane barriers during drug delivery. Although exosomes derived from mesenchymal stem cells (MSCs) have great potential for PD, MSC-derived exosomes ...
Huan Peng +12 more
semanticscholar +1 more source
Intranasal administration of insulin to humans
Diabetes Research and Clinical Practice, 1991The purpose of this review is to summarize the information and experience at present available on the intranasal administration of insulin to human subjects and to describe some of the anatomical, physiological, pharmaceutical and technological factors which can affect the absorption of insulin.
S, Gizurarson, E, Bechgaard
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Intranasal administration of melatonin starch microspheres
International Journal of Pharmaceutics, 2004Using melatonin as model drug, starch microspheres for intranasal administration were prepared by an emulsification-crosslinking technique using a uniform design to optimize preparation conditions. The entrapment ratio of melatonin in the microspheres was 11.0% and particle sizes ranged from 30 to 60 microm. Melatonin was released from the microspheres
Shirui, Mao +4 more
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Intranasal Administration of Influenza Vaccines
BioDrugs, 2000AbstractThis review article focuses on intranasal immunisation against influenza,although it also encompasses antigen uptake and processing in the nasopharyngealpassages, host defence from influenza and current influenza vaccination practices.Improvement of current vaccination strategies is clearly required; current proceduresinvolve repeated annual ...
J E, Eyles, E D, Williamson, H O, Alpar
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Intranasal estradiol administration to oophorectomized women
European Journal of Obstetrics & Gynecology and Reproductive Biology, 1991An open, dose-finding study into the effects of a new intranasal 17 beta-estradiol formulation using dimethyl-beta-cyclodextrin as a solubilizer was conducted in nine hysterectomized and oophorectomized patients with symptoms of estrogen deficiency. After nasal delivery of 0.34 mg estradiol in three patients, concentration-time curves of estradiol in ...
W A, Hermens +5 more
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Journal of the American College of Toxicology, 1994
The intranasal route has gained increased popularity in the pharmaceutical industry in recent years, particularly because of the number of new peptide therapeutic agents. This has led to a corresponding increase in both interest in and performance of toxicity (or as they are called in the pharmaceutical industry, safety assessment) studies by this ...
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The intranasal route has gained increased popularity in the pharmaceutical industry in recent years, particularly because of the number of new peptide therapeutic agents. This has led to a corresponding increase in both interest in and performance of toxicity (or as they are called in the pharmaceutical industry, safety assessment) studies by this ...
openaire +1 more source