Results 101 to 110 of about 57,277 (349)
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park +9 more
wiley +1 more source
BMC Biotechnology, 2017 Background Targeted delivery of gene therapy vectors to the mouse respiratory tract is often performed via intranasal or intratracheal administration; however, there can be a great deal of variability between these methods, which could potentially ...
Lisa A. Santry +6 more
doaj +1 more source
Pneumonia Due to Mycoplasma in Gnotobiotic Mice I. Pathogenicity of \u3cem\u3eMycoplasma pneumoniae\u3c/em\u3e, \u3cem\u3eMycoplasma salivarium\u3c/em\u3e, and \u3cem\u3eMycoplasma pulmonis\u3c/em\u3e for the Lungs of Conventional and Gnotobiotic Mice [PDF]
, 1966 Pneumonia due to mycoplasma in gnotobiotic mice. I. Pathogenicity of Mycoplasma pneumoniae, Mycoplasma salivarium, and Mycoplasma pulmonis for the lungs of conventional and gnotobiotic mice. J. Bacteriol. 92:1154–1163.
Lutsky, Irving I., Organick, Avrum B.
core +1 more source
Intranasal Delivery of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells Alleviates Memory Deficits In Sporadic Alzheimer’s Rat Models By Regulating Neurotrophic and Apoptotic Genes [PDF]
, 2021 Ebrahim Eslami +5 more
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud +3 more
wiley +1 more source
Development of biodegradable starch microspheres for intranasal delivery
Indian Journal of Pharmaceutical Sciences, 2008 Domperidone microspheres for intranasal administration were prepared by emulsification crosslinking technique. Starch a biodegradable polymer was used in preparation of microspheres using epichlorhydrine as cross-linking agent. The formulation variables were drug concentration and polymer concentration and batch of drug free microsphere was prepared ...
Yadav, A. V., Mote, H. H.
openaire +3 more sources
Annals of Neurology, EarlyView.We report the first human use of intranasal seletracetam (SEL) to prevent reflex seizures. A patient with epilepsy with reading‐induced seizures on levetiracetam (3,000 mg/day) continued to experience reading‐induced focal seizures with preserved consciousness.
Matthias J. Koepp +9 more
wiley +1 more source
Non-invasive aerosol delivery and transport of gold nanoparticles to the brain [PDF]
, 2017 Targeted delivery of nanoscale carriers containing packaged payloads to the central nervous system has potential use in many diagnostic and therapeutic applications. Moreover, understanding of the bio-interactions of the engineered nanoparticles used for
Biswas, Pratim +4 more
core +2 more sources
Advanced NanoBiomed Research, EarlyView.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Frontiers in ImmunologyEarly immune containment of mycobacteria at the infection site is key to tuberculosis (TB) vaccine development. Intranasal delivery strategies offer a promising alternative to parenteral BCG vaccination, particularly for pulmonary TB, the predominant ...
Patricia Cuenca-Lara +18 more
doaj +1 more source