Results 131 to 140 of about 57,277 (349)

Orbital Complications of Acute Rhinosinusitis in Adulthood: Predictors of Outcome and Management

The Laryngoscope, EarlyView.
In a multicenter cohort of 213 adults with orbital complications of acute rhinosinusitis, 68% required surgery and the modified Chandler classification was the strongest predictor of treatment modality. While abscess‐related and type II complications frequently necessitated surgical management, final ophthalmologic outcomes were uniformly favorable ...
Alessandro Vinciguerra, Vittorio Rampinelli, Mario Turri‐Zanoni, Marco Ferrari, Marco Valentini, Alberto Daniele Arosio, Federico Raimondi, Florian Chatelet, Stefano Taboni, Davide Mattavelli, Alberto Schreiber, Fabio Sovardi, Matteo Barucco, Lorena Di Girolami, Piergiorgio Gaudioso, Antonio Daloiso, Giulia Danè, Umberto Tanzini, Nicola Tessari, Jessica Zuppardo, Kays Burak Cakir, Yetkin Zeki Yilmaz, Yasar Unlu, Andrea Ronchi, Stefania Gallo, Francesca De Bernardi, Vasileios Chatzinakis, Argyro Leventi, Fabio Pagella, Benjamin Verillaud, Giuseppe Mercante, Apostolos Karligkiotis, Mario Bussi, Cesare Piazza, Alperen Vural, Paolo Castelnuovo, Piero Nicolai, Maurizio Bignami, Christos Georgalas, Iacopo Dallan, Philippe Herman, Paolo Battaglia   +41 more
wiley   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Intranasal Carvacrol Nanoemulsion: Stroke Imaging and Neuroprotective Study

ADMET and DMPK
Background and Purpose: Cerebral ischemia causes neuronal damage due to restricted blood flow and presents significant challenges for brain-targeted drug delivery because of the blood–brain barrier. The purpose of this study is to formulate and evaluate
Hitendra Mahajan, Ghanshyam Girnar
doaj   +1 more source

Modification of translationally controlled tumor protein-derived protein transduction domain for improved intranasal delivery of insulin

Drug Delivery, 2018
Carrier peptides, termed protein transduction domains (PTDs), serve as provide promising vehicles for intranasal delivery of macromolecular drugs. A mutant PTD derived from human translationally controlled tumor protein (TCTP-PTD 13, MIIFRALISHKK) was ...
Hae-Duck Bae, Joohyun Lee, Kyu-Yeon Jun, Youngjoo Kwon, Kyunglim Lee   +4 more
doaj   +1 more source

Nanocarriers-Assisted Needle-Free Vaccine Delivery Through Oral and Intranasal Transmucosal Routes: A Novel Therapeutic Conduit [PDF]

, 2022
Bharti Mangla, Shamama Javed, Muhammad H. Sultan, Waquar Ahsan, Geeta Aggarwal, Kanchan Kohli   +5 more
openalex   +1 more source

In Vivo Effects of N,N‐Diethyl‐Meta‐Toluamide (DEET) Exposure on Sinonasal Epithelia in a Murine Model

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Environmental factors, including airborne toxicants, are thought to contribute to the pathogenesis of chronic rhinosinusitis, although the exact mechanism is not fully understood. The purpose of this pilot study is to assess the impact of pesticide, N,N‐diethyl‐meta‐toluamide (DEET), on the sinonasal epithelium using an in vivo murine model ...
Jivianne T. Lee, Melodyanne Y. Cheng, Eri S. Srivatsan, Neda A. Moatamed, Saroj K. Basak   +4 more
wiley   +1 more source

Intranasal delivery of rotigotine to the brain for treating Parkinson’s disease

Fundamental Research
: The development of sustainable and non-invasive method for delivering drugs to the brain is crucial for the effective treatment of Parkinson’s disease (PD).
Dandan Kou, Keyang Xu, Jiahui Yin, Ning Wang, Ruru Zhang, Jianfeng Zeng, Mingyuan Gao   +6 more
doaj   +1 more source

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease [PDF]

, 2008
Leah R. Hanson, William H. Frey
openalex   +1 more source

Intranasal delivery of a synthetic Entamoeba histolytica vaccine containing adjuvant (LecA + GLA-3 M−052 liposomes): In vitro characterization

, 2022
Brynn Murphy, John Z. Chen, Michael Rolo, Mohamed Eldam, Lynn Jordan, Sandra J. Sivananthan, Robert Kinsey, Jeffrey A. Guderian, Karl Pedersen, Mayuresh M. Abhyankar, William A. Petri, Christopher B. Fox, Warren H. Finlay, Reinhard Vehring, Andrew R. Martin   +14 more
openalex   +2 more sources

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source