Intranasal delivery of mRNA expressing newly identified Acinetobacter baumannii antigens protects against bacterial lung disease. [PDF]
Higham SL +16 more
europepmc +1 more source
Investigating Strategies to Enhance the Aqueous Solubility of Ketamine HCl for Intranasal Delivery. [PDF]
Idoudi S +6 more
europepmc +1 more source
Multilayer Adjuvanted Influenza Protein Nanoparticles Improve Intranasal Delivery and Antigen-Specific Immunity. [PDF]
Park J +12 more
europepmc +1 more source
Novel intranasal delivery of sihosogansan demonstrates rapid antidepressant activity via GABAergic and BDNF/TrkB pathways: identification of potential bioactive quality markers. [PDF]
Tran KN +6 more
europepmc +1 more source
Uptake of Mesenchymal Stem Cell-Derived Exosomes in Mouse Brain through Intranasal Delivery. [PDF]
Zhang Z +9 more
europepmc +1 more source
Intranasal delivery of blackberry-loaded Chitosan nanoparticles for antipsychotic potential in Ketamine-induced schizophrenia in rats. [PDF]
George MY +14 more
europepmc +1 more source
Intranasal Delivery of a Ghrelin Mimetic Engages the Brain Ghrelin Signaling System in Mice.
Poelman R +4 more
europepmc +1 more source
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Intranasal delivery of antipsychotic drugs
Schizophrenia Research, 2017Antipsychotic drugs are used to treat psychotic disorders that afflict millions globally and cause tremendous emotional, economic and healthcare burdens. However, the potential of intranasal delivery to improve brain-specific targeting remains unrealized. In this article, we review the mechanisms and methods used for brain targeting via the intranasal (
Yogesh K. Katare +7 more
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Intranasal delivery: Physicochemical and therapeutic aspects
International Journal of Pharmaceutics, 2007Interest in intranasal (IN) administration as a non-invasive route for drug delivery continues to grow rapidly. The nasal mucosa offers numerous benefits as a target issue for drug delivery, such as a large surface area for delivery, rapid drug onset, potential for central nervous system delivery, and no first-pass metabolism.
Henry R, Costantino +4 more
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