Results 141 to 150 of about 32,558 (212)

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

Drug Testing and Analysis, Volume 18, Issue 11, Page 1456-1469, November 2026.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda, Marc Machnik, Mario Thevis, Yohei Minamijima, Gary Ngai‐Wa Leung, Motoi Nomura, Fumiaki Mizobe, Yuhiro Ishikawa, Kazuhiro Kamiya, Pierre‐Louis Toutain   +9 more
wiley   +1 more source

Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer's Disease. [PDF]

Int J Nanomedicine
Sun C, Sha S, Shan Y, Gao X, Li L, Xing C, Guo Z, Du H.   +7 more
europepmc   +1 more source

Plant‐Derived Probiotics From Fermented Foods: Current Evidence on Antiviral Mechanisms and Gut–Lung Axis Modulation

Food Frontiers, Volume 7, Issue 6, November 2026.
Plant‐derived probiotics from fermented foods exert anti‐respiratory virus effects via immune regulation, antiviral metabolites, and gut–lung axis, highlighting their advantages, key technologies, and application prospects. ABSTRACT Respiratory viral infections represent a major global public health threat, causing widespread morbidity, mortality, and ...
Yinghao Xing, Yaoyuan Hu, Yingying Ma, Peng Yao, Jingjing Jiang, Jiao Guo, Shuangmei Liu   +6 more
wiley   +1 more source

Alpinia oxyphylla Miq.: Chemical Constituents, Neuroprotective and Metabolic Effects, and Translational Challenges—A Review of Preclinical Evidence

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Alpinia oxyphylla Miq. (AOM), a medicinal and edible resource, contains diphenylheptanoids, polysaccharides, flavonoids, terpenoids, and phenolic acids. These constituents exert multi‐target synergistic effects by modulating neuroinflammation, oxidative stress, and the PI3K/Akt pathway, thereby improving Alzheimer's disease, Parkinson's disease, and ...
Ziyan Yang, Hemei Yuan, Dengyou Nie, Jun Sheng, Titi Liu, Huanhuan Xu   +5 more
wiley   +1 more source

Extracellular Vesicles Enhance The Coupling of Neurogenesis and Angiogenesis and Neurological Recovery By Transfer of Micrornas After Stroke

Journal of Extracellular Biology, Volume 5, Issue 11, November 2026.
➢Extracellular vesicles (EVs) mediate the coupling of angiogenesis and neurogenesis. ➢Ischemic cerebral endothelial cell (CEC) derived EVs enhance neurogenesis. ➢EVs derived from either non‐ischemic or ischemic neural stem cells (NSCs) promote in vitro angiogenesis. ➢EV‐transmitted miRNAs regulate stroke‐induced neurogenesis and angiogenesis.
Xianshuang Liu, Wan Long Pan, Hua Teng, Xin Jiang, Yi Zhang, Xinli Wang, Amy Kemper, Michael Chopp, Zheng Gang Zhang   +8 more
wiley   +1 more source

Intranasal delivery of engineered anti-SARS-CoV-2 extracellular vesicles therapeutically represses lung infection and inflammation. [PDF]

Drug Deliv Transl Res
Idris A, Idris A, Shrivastava S, Gao W, Supramaniam A, Tayyar Y, West NP, Kelly G, Acharya D, McMillan NAJ, Morris KV.   +10 more
europepmc   +1 more source

Metformin at the Time of COVID‐19 Infection and Risk of Long COVID: A Target Trial Emulation Study

Journal of Medical Virology, Volume 98, Issue 11, November 2026.
ABSTRACT Our objective was to evaluate metformin prescribed at the time of SARS‐CoV‐2 infection on the risk of developing Long COVID (LC) in electronic health record data. We conducted a new user analysis of metformin prescribed within 6 days of documented infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) versus experimental ...
Carolyn T. Bramante, Til Stürmer, Jared D. Huling, John B. Buse, Christopher Lindsell, Thomas Stewart, Russell L. Rothman, David Sahner, Sarah E. Dunsmore, Eric Topol, Talia D. Wiggen, Steve Makkar, Andrew Toler, Taylor Estepp, Steven G. Johnson, N3C Consortium   +15 more
wiley   +1 more source

Intranasal delivery of metformin using metal-organic framework (MOF)-74-Mg nanocarriers. [PDF]

Adv Compos Hybrid Mater
Yuan M, Han Z, Somayaji Y, Nguyen N, Hu H, Madhu LN, Attaluri S, Kodali M, Yang Y, Hsu YC, Ahuja A, Srinivasan R, Pellois JP, Zhou HC, Shetty AK, Wang Y.   +15 more
europepmc   +1 more source

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He, Jingjing Zeng, Guoqing Wang, Yuxin Li, Feng Zhang   +4 more
wiley   +1 more source

Intranasal delivery of engineered extracellular vesicles promotes neurofunctional recovery in traumatic brain injury. [PDF]

J Nanobiotechnology
Li P, Sun S, Zhu X, Liu X, Yin R, Chen Y, Chang J, Ye L, Gao J, Zhao X, Xu H, Wang Y, Zuo W, Sun Z, Wang S, Zhang X, Wei J, Zhao RC, Han Q.   +18 more
europepmc   +1 more source