Results 151 to 160 of about 158,913 (343)

Influence of variability in starting materials quality on stability of finished drug products: a quality-by-design factor and response [PDF]

, 2012
The use of ill selected excipients in drug formulations can have a significant influence on the overall stability. Therefore, evaluation of chemical and physical excipient compatibility with the API has become a major part in the development of new drug ...
Bauters, Tieneke, D'Hondt, Matthias, De Spiegeleer, Bart, Robays, Hugo, Vandenbroucke, Johan, Wynendaele, Evelien   +5 more
core   +1 more source

Infectious Complications During Early Treatment of Childhood Acute Lymphoblastic Leukemia—A Comparison Between the ALLTogether and NOPHO ALL‐2008 Protocols

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Infection remains the most common treatment‐related toxicity of childhood ALL, emphasizing the need to identify patients at risk and to tailor treatment strategies accordingly. Aims The primary aim was to compare infectious toxicity during early treatment for childhood ALL following the ALLTogether and NOPHO ALL‐2008 (ALL‐2008 ...
Hannah van Bunningen, Johannes Fermér, Arja Harila, Susanna Ranta, Isabella Donnér, Anne Wretman, Hartmut Vogt, Anna Sällfors Holmqvist, Anders Valind, Ludvig Henriksson, Jonas Abrahamsson, Magnus Borssén, Anna Nilsson, Mats Heyman   +13 more
wiley   +1 more source

Shared Sociodemographic Risk Factors for Neurocognitive Dysfunction in Children With Cancer and Blood Disorders

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background To investigate the role of social determinants of health (SDoH) in neurocognitive functioning among children with acute lymphoblastic leukemia (ALL), central nervous system (CNS) tumors, and sickle cell disease (SCD). Procedure Fifty‐eight child‐caregiver dyads participated.
Claire E. F. Miller, Jamie Neiman Luehring, Elizabeth B. Molina Kuna, Shweta Bhatia, Adam L. Green, Bruce E. Compas   +5 more
wiley   +1 more source

Stability and Compatibility of Drug Mixtures from Intrathecal Pump Using High Performance Liquid Chromatography

, 2020
Saba Javed
openalex   +1 more source

Catheter Access Port (Computed Tomography) Myelography in Intrathecal Drug Delivery Troubleshooting: A Case Series of 70 Procedures [PDF]

, 2020
Elmar M. Delhaas, Biswadjiet S. Harhangi, Sander P.G. Frankema, Frank Huygen, Aad van der Lugt   +4 more
openalex   +1 more source

Same-Day and Next-Day Pain and Nausea Parameters after Intrathecal Morphine for Abdominal Panniculectomy and Mastectomy Post-Bariatric Surgery [PDF]

, 2021
Brian A. Williams, James W. Ibinson, Michael Cellurale, Toby Nalepka, Devra B. Becker   +4 more
openalex   +1 more source

Early Toxicity in Childhood Acute Lymphoblastic Leukemia: A Comparison of NOPHO ALL2008 and ALLTogether Protocols in Sweden

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The European ALLTogether protocol for childhood acute lymphoblastic leukemia, initiated in Sweden 2019, introduced earlier asparaginase during induction, dexamethasone instead of prednisone for all patients, and omitted anthracyclines from low‐risk induction to reduce treatment‐related toxicity.
Johannes Fermér, Hannah van Bunningen, Otto Zhou, Jonas Abrahamsson, Magnus Borssen, Isabella Donnér, Mats Heyman, Anna Sällfors Holmqvist, Anders Valind, Hartmut Vogt, Susanna Ranta, Arja Harila   +11 more
wiley   +1 more source

Efficiency of spinal anesthesia versus general anesthesia for lumbar spinal surgery: a retrospective analysis of 544 patients. [PDF]

, 2017
BACKGROUND: Previous studies have shown varying results in selected outcomes when directly comparing spinal anesthesia to general in lumbar surgery. Some studies have shown reduced surgical time, postoperative pain, time in the postanesthesia care unit ...
Attiah, Mark A., Kallan, Michael J., Koenigsberg, Rebecca, Kofke, W. Andrew, Kositratna, Guy, Marcotte, Paul J., Pierce, John T., Syre, Peter, Welch, William C., Wyler, MD, David   +9 more
core   +1 more source

Weathering the storms of climate change: Preparing persons with disabilities and the physiatrists who provide their care for extreme hurricanes

PM&R, EarlyView.
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae, James M. Shultz, J. Marshall Shepherd, Zelde Espinel, Lauren T. Shapiro   +4 more
wiley   +1 more source

Daflon Enhances Morphine Analgesia and Mitigates Tolerance in a Rat Neuropathic Pain Model

Pharmaceuticals
Objective: Morphine is a widely used analgesic for severe pain, but tolerance is a major challenge in long-term pain management. This study examined the potential of Daflon® to enhance morphine’s pain-relieving effects and to reduce tolerance in a rat ...
Lokesh Kumar Mende, Meng-Lin Lee, Yaswanth Kuthati, Shu-Yi Koh, Chih-Shung Wong   +4 more
doaj   +1 more source