Results 161 to 170 of about 74,181 (306)

The Clinical Research Landscape of Intracranial Nicardipine for Aneurysmal Subarachnoid Hemorrhage: Insights From Bibliometric Analysis

Drug Design, Development and Therapy
Guangtang Chen,1,* Yi Cao,1,2,* Xiaolin Du,3,* Junshuan Cui,1 Xi Zeng,1 Hua Yang,1 Zeguang Ren,1 Kaya Xu1 1Department of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China; 2School of ...
Chen G, Cao Y, Du X, Cui J, Zeng X, Yang H, Ren Z, Xu K   +7 more
doaj  

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Intrathecal IgG synthesis as a biomarker for CNS involvement in anti-GQ1b antibody syndrome: a case report and hypothesis-generating treatment framework. [PDF]

Front Immunol
Zhou H, Guo X.
europepmc   +1 more source

Intrathecal baclofen [PDF]

Developmental Medicine & Child Neurology, 2010
openaire   +2 more sources

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Clinical outcomes of intrathecal anti-PD-1 therapy with or without whole-brain radiotherapy in melanoma leptomeningeal metastasis: a multicenter retrospective study. [PDF]

Front Immunol
Zhen J, Zhang R, Li D, Ding Y, Wen X, Yang Y, Wang H, Lai M, Zhang X, Cai L, Li J.   +10 more
europepmc   +1 more source

Clobazam to preserve meaningful engagement in prolonged disorder of consciousness with concurrent seizure disorder

PM&R, EarlyView.
Tatiana Bernstein, Zachary Miklja, Tiffany Wood, Joshua Startup   +3 more
wiley   +1 more source

Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens

Cell Proliferation, EarlyView.
In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu, Bingyu Cai, Tingting Gao, Wumei Wei, Liu Wang, Qi Zhou, Wei Li, Jie Hao, Jun Wu   +8 more
wiley   +1 more source

Comparative pharmacotherapeutic efficacy and dose-related safety profiles of intrathecal baclofen: a systematic review and meta-analysis in neurological spasticity. [PDF]

Front Pharmacol
Chen H, Lei H, Yu Y, Ma C, Wang F.
europepmc   +1 more source

Myelopathy following intrathecal chemotherapy in a patient with acute lymphoblastic leukemia: a case report. [PDF]

Front Oncol
Li J, Mao X, Yu F, Huang Y, Wang Y, Li J, Li L, Wang B.   +7 more
europepmc   +1 more source