Results 181 to 190 of about 99,994 (292)

Intracranial Hypotension Following Spinal Manipulation: A Case Report and Scoping Review of the Literature

Brain and Behavior, Volume 16, Issue 5, May 2026.
Abstract Purpose Spinal manipulative therapies, including chiropractic and osteopathic maneuvers, are widely practiced for musculoskeletal complaints. However, rare but serious complications such as cerebrospinal fluid (CSF) leak with subsequent intracranial hypotension (IH) have been described.
Marina Romozzi, Matteo Palermo, Fabio Zeoli, Federico Tosto, Catello Vollono, Giuseppe Garignano, Francesco Signorelli   +6 more
wiley   +1 more source

Combined spinal cord stimulation and intrathecal Morphine-Sufentanil therapy for refractory cancer pain: a case report. [PDF]

Front Aging
Zhang ZS, Zhang Y, Wu J.
europepmc   +1 more source

GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang, Bingjie Wang, Yujun Dong, Qingya Wang, Qian Wang, Jialin Zhu, Qingyun Wang, Na Han, Yuan Li   +8 more
wiley   +1 more source

Docosahexaenoic Acid Attenuates Visceral Pain by Suppressing Spinal CXCL10/CXCR3/ERK Signaling. [PDF]

Nutrients
Yin X, Jiang A, Han Y, Qu J, Zhao J, Gong H, Luo X, Li X, Lu Y.   +8 more
europepmc   +1 more source

Behavioural Characterisation and Pharmacological Validation of an Incisional Wound‐Related Pain Model

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Wound‐related pain represents a significant unmet clinical need. To advance its understanding and treatment, there is a need for a validated preclinical model for the study of wound‐related pain in both sexes. Methods A 1.2 cm incision was created on the hairy skin of the dorsum of male and female Sprague–Dawley rats posterior to L4.
Catherine R. Healy, Maria C. Redmond, Mary Hopkins, Georgina Gethin, Abhay Pandit, David P. Finn   +5 more
wiley   +1 more source

Intrathecal Fluorescein in the Surgical Management of Spontaneous Cerebrospinal Fluid Leaks: A Case Report. [PDF]

Cureus
Costa S, Bessa S, Almeida J, Feliciano T, Lino J.   +4 more
europepmc   +1 more source

The Efficacy and Toxicity of CNS Prophylaxis in Diffuse Large B‐Cell Lymphoma (CLSG‐CNS‐01): A Randomized, Multicenter, Prospective Phase 3 Trial

Hematological Oncology, Volume 44, Issue 3, May 2026.
ABSTRACT The randomized, multicenter, prospective Phase 3 trial (NCT02777736) evaluated central nervous system (CNS) prophylaxis using either intravenous (i.v.) or intrathecal (i.t.) methotrexate (MTX) in diffuse large B‐cell lymphoma (DLBCL). Treatment consisted of six cycles of R‐CHOP + 2xR or DA‐EPOCH‐R + 2xR. Patients with intermediate or high‐risk
H. Mocikova, L. Gaherova, T. Jancarkova, A. Suri, A. Janikova, K. Steinerova, D. Belada, R. Pytlik, J. Duras, M. Trnkova, P. Blahovcova, T. Kozak, M. Trneny   +12 more
wiley   +1 more source

CSF proteomics identifies ADGRG1 as a predictive biomarker of intrathecal immune checkpoint inhibitor response in leptomeningeal metastasis. [PDF]

J Immunother Cancer
Wang L, Yang G, Lei H, Zhang Y, Li B, Liu M, Huang Y, Chen X, Tai P, Pan Z.   +9 more
europepmc   +1 more source

2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot, Forbes D. Porter, Tatiana Bremova‐Ertl, Uma Ramaswami, Caroline Hastings, Bénédicte Héron, Justin Hopkin, Joella Melville, Hernan Amartino, Mireia del Toro, Federica Deodato, Fatih Ezgü, Paul Gissen, James B. Gibson, Can Ficicioglu, Roberto Giugliani, Orna Staretz‐Chacham, Frances Platt, Nathalie Guffon, Kristina Julich, Nikola Kresojević, Anna Lehman, Yann Nadjar, Susanne A. Schneider, Simon Jones, Eugen Mengel, Michel Tchan, Mark Walterfang, Ozlem Goker‐Alpan, Charlotte Dawson, Sandra Cowie, Toni Mathieson, Elizabeth Berry‐Kravis, Marc C. Patterson   +33 more
wiley   +1 more source

A Study on the Analgesic Effects of Two Different Doses of Morphine Added to Intrathecal Levobupivacaine in Cesarean Section: A Randomized Double-Blind Study. [PDF]

Cureus
Ayya SS, Jarathi A, Lakshmi Haritha M, Chikkala RKP, Garre S.   +4 more
europepmc   +1 more source