Results 191 to 200 of about 76,887 (294)

Intrathecal IgG synthesis as a biomarker for CNS involvement in anti-GQ1b antibody syndrome: a case report and hypothesis-generating treatment framework. [PDF]

Front Immunol
Zhou H, Guo X.
europepmc   +1 more source

Two Blastic Plasmacytoid Dendritic Cell Neoplasms treated with the CD123‐targeted agent Tagraxofusp presenting divergent outcomes

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sven C. Engler, Elisabeth M. Walde, Edgar Jost, Amir S. Yazdi, David Kluwig   +4 more
wiley   +1 more source

Newly identified human aminoacyl‐tRNA synthetase complex interacting multifunctional protein 2 (AIMP2) loss‐of‐function mutations cause neurodevelopmental defects linked to cell death in a zebrafish model

The FEBS Journal, EarlyView.
Human AIMP2 mutations lead to severe neurodevelopmental defects and brain atrophy. Using patient‐derived fibroblasts from two individuals, we show decreased AIMP2 protein levels and overall protein synthesis. In a zebrafish loss‐of‐function model, the lack of AIMP2 leads to an increase in cell death and results in smaller brains.
Patrick Mullen, Shenela Lakhani, Joshua Appelbaum, DéJenaé See, Pryce Patterson, Collin M. MacLeod, Alexandra George, Reza Maroofian, Margaret E. Ross, Christopher Francklyn, Alicia M. Ebert   +10 more
wiley   +1 more source

Effect of intrathecal injection of methotrexate and dexamethasone on quality of life and cognitive function in patients with intracranial tumors. [PDF]

Am J Transl Res
Dong H, Zhang Y, Liao R.
europepmc   +1 more source

Re‐evaluation of the dinosaur tail sign: Analysis of spinal magnetic resonance imaging signs in patients with chronic post–dural‐puncture headache

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to assess magnetic resonance imaging (MRI) findings of the lumbar spine in patients with chronic post–dural‐puncture headache. Background Post–dural‐puncture headache is a common complication after dural puncture usually resolving within 14 days.
Charlotte Zander, Horst Urbach, Katharina Wolf, Amir El Rahal, Florian Volz, Christian Fung, Laura Krismer, Hansjörg Mast, Jürgen Beck, Niklas Lützen   +9 more
wiley   +1 more source

Intrathecal EP4 Antagonist Alleviates Neuronal and Glial Activation and Hyperalgesia in a Mouse Model of Endometriosis. [PDF]

J Pain Res
Fan P, Xiong W, Chen Y, Bai Y, Li T.
europepmc   +1 more source

The relationship between psychosocial risk and neurocognitive functioning early after childhood central nervous system tumour diagnosis

Journal of Neuropsychology, EarlyView.
Abstract Neurocognitive impairments are common in paediatric central nervous system (CNS) tumours and can relate to clinical and demographic factors. The impact of social or environmental factors, such as family psychosocial risk, is less well understood.
Jessica Beamish, Riley M. Damiano, Josephine Drijver, Femke Aarsen, Martha Grootenhuis, Marita Partanen   +5 more
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Case Report: Isolated leptomeningeal relapse after systemic control in PALB2-altered pancreatic cancer. [PDF]

Front Med (Lausanne)
Yuan J, Xu Y, Zhou Q, Yuan G, Ye M.
europepmc   +1 more source

Clinical outcomes of intrathecal anti-PD-1 therapy with or without whole-brain radiotherapy in melanoma leptomeningeal metastasis: a multicenter retrospective study. [PDF]

Front Immunol
Zhen J, Zhang R, Li D, Ding Y, Wen X, Yang Y, Wang H, Lai M, Zhang X, Cai L, Li J.   +10 more
europepmc   +1 more source