Results 191 to 200 of about 99,994 (292)

Unifying the Communities of Early‐Onset Glycogen Storage Disease Type IV and Adult Polyglucosan Body Disease Through a Genetic Prevalence Study of GBE1‐Related Disease

JIMD Reports, Volume 67, Issue 3, May 2026.
Genetic prevalence study of glycogen storage disease type IV. In collaboration with the Rare Genomes Project at the Broad Institute of MIT and Harvard and the APBD Research Foundation, this study queried and curated variants in GBE1 from ClinVar, HGMD, and gnomAD to calculate the genetic prevalence of glycogen storage disease type IV (GSD IV).
Rebecca L. Koch, H. Orhan Akman, Erin Chown, Deberah Goldman, Jeff Levenson, Qing Lu, Lindsay T. Michalovicz Gill, Matthew Morgan, Jennifer L. Orthmann‐Murphy, Natacha T. Pires, Rebecca Reef, Harriet Saxe, Moriel Singer‐Berk, Samantha Baxter   +13 more
wiley   +1 more source

Development and Clinical Evaluation of an LC-MS/MS Method for the Determination of Isoniazid in Cerebrospinal Fluid from Tuberculous Meningitis. [PDF]

Infect Drug Resist
Xin M, Liang J, Lin M, Wang X, Hou W, Zhong L, Ma X, Ji X.   +7 more
europepmc   +1 more source

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

MedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang, Zijiao Tian, Zhaoquan Wang, Zerui Yang, Ziyao Wang, Zikang Wang, Ziqing Wang, Xingyuan He, Yu Yan, Yuanfeng Gong, Siyuan Xu, Xinyi Li, Guihua Tian   +12 more
wiley   +1 more source

Development of a Glymphatic Pathway-based Rat Model for Cancer Metastasis from Brain to Lung. [PDF]

In Vivo
Sreejith A, Xiao H, Howson I, Bocchetta M, Aryal M.   +4 more
europepmc   +1 more source

A Novel Perspective on Multiple Sclerosis: Morphological Shifts in Immune Cell Populations

Progress in Neurology and Psychiatry, Volume 30, Issue 2, May 2026.
ABSTRACT This study aims to investigate expanded hematological data in multiple sclerosis (MS) and evaluate their association with disease severity. A total of 190 patients participated in the study. For this purpose, expanded hemocytometry data were compared between 120 patients diagnosed with MS and 70 healthy controls.
Hayrettin Yavuz, Özlem Kayım Yıldız, Serkan Bolat, Demet Kablan, Selda Özer, Kübra Doğan, Şeyda Figül Gökçe, Meltem Kurt Yenihan, Halef Okan Doğan   +8 more
wiley   +1 more source

Mechanistic multiphysics modeling reveals how blood pulsation drives CSF flow, pressure, and brain deformation under physiological and injection conditions. [PDF]

Fluids Barriers CNS
Li Z, Feng K, Gomez H.
europepmc   +1 more source

Cardiopulmonary arrest following extradural analgesia and suspected secondary sympathetic blockade in a critically ill dog

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract An 8‐year‐old, male, entire Cocker Spaniel presented to the Queen Mother Hospital for Animals for treatment of an iatrogenic septic uroabdomen secondary to traumatic urinary catheterisation. After initial stabilisation, it underwent diagnostic imaging and definitive surgical correction comprising a cystotomy and bladder reconstruction.
Joe Simon, Manuel Enrique Herrera‐Linares, Hannah Louise Matson, Cristina Bianchi   +3 more
wiley   +1 more source

Intrathecal injection of rituximab inhibits microglial M1 polarisation to alleviate neuropsychiatric SLE symptoms via the cAMP/PKA/CREB signalling pathway. [PDF]

Lupus Sci Med
Li C, Yu W, Li A, Chen Y, Zhao J, Lin Y, Pan XL, Tian M.   +7 more
europepmc   +1 more source

Adverse Effects Associated With Spinal Versus General Anaesthesia for Hip and Knee Arthroplasties: Protocol for a Systematic Review

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 5, May 2026.
ABSTRACT Background Spinal and general anaesthesia are the most common anaesthetic methods for hip and knee arthroplasties. Differences in their effects on short‐ and long‐term postoperative outcomes, including mortality morbidity, and adverse events, remain uncertain.
Anne Sofie Nautrup Therkelsen, Hans Bredgaard Christensen, Anne‐Lene Kjældgaard, Camilla Godthaab, Christina Dam Bjerregaard Sillassen, Troels Haxholdt Lunn, Daniel Hägi‐Pedersen, Claus Varnum, Martin Lindberg‐Larsen, Kasper Højgaard Thybo, Janus Christian Jakobsen, Ole Mathiesen   +11 more
wiley   +1 more source

Standard work tools for managing pediatric baclofen pump infections and withdrawal. [PDF]

Childs Nerv Syst
Jain R, Weiss BE, Snider E, Mossner JM, Raskin JS.   +4 more
europepmc   +1 more source