Results 211 to 220 of about 76,887 (294)

Optimal intrathecal morphine dosing for revision hip arthroplasty: an observational study. [PDF]

Anaesthesia
Patel S, Paschou V, Quinlan J, Kendrick B, Suarez N.   +4 more
europepmc   +1 more source

SGIP1 limits cannabinoid receptor signalling in spinal nociceptive synapses and modulates analgesia during neuroinflammation

The Journal of Physiology, EarlyView.
Abstract figure legend SGIP1 constrains presynaptic cannabinoid signalling in the spinal dorsal horn and limits cannabinoid analgesia after inflammation. In vivo (both sexes), SGIP1 KO mice showed a higher baseline heat threshold but unchanged mechanical sensitivity.
Denisa Dresslerova, Monica Pontearso, David Muzik, Anirban Bhattacharyya, Jakub Slepicka, Daniel Vasconcelos, Jiri Palecek, Diana Spicarova   +7 more
wiley   +1 more source

Intrathecal pump therapy: a retrospective cohort with over 1500 pump-years of follow-up. [PDF]

Brain Spine
Matthijs V, Vandamme S, Nagels W, De Coster O, Hanssens K, Maenhoudt W, Van Lerbeirghe J, Van Damme O, Vanhauwaert D.   +8 more
europepmc   +1 more source

Epstein-Barr virus shapes intrathecal Th1/Th17 immunity and parenchymal involvement in neuro-Behçet's disease. [PDF]

Front Immunol
Ben Laamari R, Saied Z, Maghrebi O, Bahrini K, Bekir J, Stiti A, Driss A, Rezig D, Barbouche MR, Ben Sassi S, Belghith M.   +10 more
europepmc   +1 more source

Leptomeningeal carcinomatosis arising from esophageal cancer: a systematic review of the literature. [PDF]

Dis Esophagus
Mylonakis A, Stylios D, Tsilimigras D, Charalampopoulos G, Kotsantis I, Liontos M, Georgakopoulos I, Schizas D.   +7 more
europepmc   +1 more source

Association Between Cerebrospinal Fluid Ghrelin Levels and Depressive Symptoms is Moderated by Smoking: A Case‐Control Study

International Journal of Methods in Psychiatric Research, Volume 35, Issue 4, December 2026.
ABSTRACT Objective Smoking has been linked to both peripheral ghrelin levels and depressive symptoms. However, the association between cerebrospinal fluid (CSF) ghrelin levels and depressive symptoms, and the moderating role of smoking, remains unclear. This study aims to investigate the specific relationship among the three categories. Methods In this
Yueling Hu, Lingling Chen, Chunshui Yu, Yu‐Hsin Chen, Xingguang Luo, Yimin Kang, Li Chen, Yanlong Liu, Jue He, Fan Wang, Zengzeng Zhang   +10 more
wiley   +1 more source

Diagnosis-Treatment Discordance in Suspected Lyme Neuroborreliosis: A Retrospective Cohort Study from a Romanian Tertiary Centre (2008-2025). [PDF]

Pathogens
Cheran CA, Tirlescu LG, Panciu AM, Hristea A.   +3 more
europepmc   +1 more source

Characterization of the Lysophosphatidic Acid Receptor 5 Antagonist RLPA‐76 as a Novel Analgesic in Male Rats and Mice

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Clinically used analgesics such as gabapentinoids and opioids have limited efficacy and adverse effects like abuse liability, and there is a dire need for novel analgesics with improved safety profiles. Since lysophosphatidic acid can induce neuropathic pain in rodents, LPA receptor antagonists have been investigated as potential analgesics ...
Kristen L. Woodhouse, Maowei Wang, Sai Ganesh Balaji Venkata Anupindi, Olatunbosun Adeoke, Dehui Zhang, Yanan Zhang, Jun‐Xu Li   +6 more
wiley   +1 more source

Pericapsular nerve group block with phenol for non‐operative hip fracture management in patients living with frailty: a prospective multicentre cohort study

Anaesthesia, Volume 81, Issue 12, Page 1673-1685, December 2026.
Summary Introduction The incidence of hip fractures is rising with the ageing population. For patients living with severe frailty and limited life expectancy, non‐operative management is increasingly considered after shared decision‐making. Given the limited availability of long‐term analgesic options, alternative techniques are needed.
Rachel J. H. Smits, Marte I. Lommerse, Hugo H. Wijnen, Lennart G. Wasmoeth, Glenn van de Vossenberg, Gezina T. M. L. Oei, Henk J. Schuijt, Kris C. P. Vissers, Hanna C. Willems, Jan Willem Kallewaard, Selina E. I. van der Wal, the Dutch‐PENG registry collaborators, Gert R. Roukema, Dawi Van der Stap, J.S.H.A. (Seppe) Koopman, Bart P.A. Spaetgens, Renée Brüggemann, Nicole Lefel, Manon Vugts, Nikki M.F. Noorda, Vincent Van Dongen, Hidde Krot, Nicole Grupa, Daisy Hoofwijk, Léon Timmerman   +24 more
wiley   +1 more source