Results 221 to 230 of about 74,181 (306)

Comments on "Low-Dose Morphine Intrathecal Analgesia in Elderly Patients with Hip Fracture Undergoing Single Spinal Anesthesia: A Randomized Controlled Trial" [Letter]. [PDF]

Local Reg Anesth
Qiao W, Meng J.
europepmc   +1 more source

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3180-3190, September 2026.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan, Christian Bach Vase, Christina Mortensen, Liv Andres‐Jensen, Dorte Aalund Olsen, Jonna Skov Madsen, Kjeld Schmiegelow, Rene Mathiasen, Tore Bjerregaard Stage   +8 more
wiley   +1 more source

A TRIP‐nano killer silencing the pain pacemakers

The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley   +1 more source

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3002-3011, September 2026.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

Combined intrathecal fentanyl and morphine for postoperative analgesia after total knee arthroplasty: a randomised controlled trial. [PDF]

BMC Anesthesiol
Park SK, Lee J, Gim DY, Park J, Kim HC.
europepmc   +1 more source

A Phase Ib Case Series Using Bortezomib With Chemotherapy in Atypical Teratoid/Rhabdoid Tumors

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Atypical teratoid/rhabdoid tumors (ATRTs) are aggressive pediatric brain tumors that are sensitive to proteasome inhibitors in preclinical models. We evaluated the feasibility of combining the proteasome inhibitor, bortezomib, with chemotherapy.
Wan‐Ling Ho, Ming‐Yun Hsieh, Yu‐Mei Liao, Shyh‐Shin Chiou, Her‐Shyong Shiah, Chang‐Hsu Chiang, Shiann‐Tarng Jou, Hsiu‐Ju Yen, Yi‐Yen Lee, Muh‐Lii Liang, Ting‐Chi Yeh, Yu‐Cheng Chou, Fang‐Liang Huang, Shu‐Huey Chen, Hsin‐Lun Lee, Chia‐Chun Kuo, Yi‐Shan Yang, Shu‐Mei Chen, Min‐Lan Tsai, Hsi Chang, Kevin Li‐Chun Hsieh, Chia‐Lang Fang, Chia‐Yau Chang, Jinn‐Li Wang, Chu‐Chin Chen, Joon‐Khim Loh, Pei‐Chin Lin, Tzu‐Chin Lin, Shih‐Chung Wang, Yi‐Fang Tu, Chao‐Neng Cheng, Jimmy Ming‐Jung Chuang, Huy Minh Tran, Shian‐Ying Sung, Irving Lai, Kuo‐Sheng Wu, James S. Miser, Yen‐Lin Liu, Tai‐Tong Wong   +38 more
wiley   +1 more source

A rare case of Lung adenocarcinoma complicated with leptomeningeal and brain parenchymal metastasis: case report and review of the literature. [PDF]

Front Oncol
Xu X, Su Q, Cheng Z, Li Y.
europepmc   +1 more source

Efficacy and Safety of CAR‐T Cell Therapy in Relapsed/Refractory B‐Cell Acute Lymphoblastic Leukemia With Central Nervous System Involvement

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Central nervous system (CNS) involvement in B‐cell acute lymphoblastic leukemia (B‐ALL) is associated with relapse, treatment refractoriness, and poor prognosis. Although chimeric antigen receptor (CAR) T cell therapy has demonstrated remarkable efficacy in relapsed/refractory (R/R) B‐ALL, its efficacy and safety in CNS leukemia (CNSL) remain ...
Yanghong Yu, Hui Xu, Lei Xue, Xingbing Wang   +3 more
wiley   +1 more source

Intrathecal Ziconotide Long-Term Management in Chronic Postamputation Pain. [PDF]

Case Rep Anesthesiol
Mateos RG, Tous NC, Katati M, Carrasco BL, García MAS.   +4 more
europepmc   +1 more source

Prolonged Headache in a 13‐Year‐Old Girl With Acute Lymphoblastic Leukemia: A Case of Possible Neuroinflammatory Complication Responsive to Intravenous Immunoglobulin

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Neurological complications in pediatric acute lymphoblastic leukemia (ALL) may result from disease, CNS involvement, or treatment. We report a 13‐year‐old girl with persistent headache and blurred vision suggestive of raised intracranial pressure.
Amereh Hadizadeh, Hossein Esfahani, Firozeh Hosseini, Afshin Fayyazi, Nasibeh Ghalandari   +4 more
wiley   +1 more source