Results 151 to 160 of about 76,887 (294)

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Patient Safety and Organisational Accountability: Reassessing Criminal Liability Frameworks in Healthcare

The Modern Law Review, EarlyView.
Serious harm in healthcare often results from systemic failures, yet criminal accountability remains largely addressed through homicide law, gross negligence manslaughter and health‐and‐safety offences, frameworks that emphasise individual culpability and are ill‐suited to addressing organisational failings.
Sarah Bennett, Amel Alghrani
wiley   +1 more source

PROSPECT guideline for total hip arthroplasty: updated systematic review and procedure‐specific postoperative pain management recommendations

Anaesthesia, EarlyView.
Summary Introduction The Procedure Specific Postoperative Pain Management (PROSPECT) collaboration develops evidence‐based recommendations integrating analgesic efficacy, safety and functional recovery. Since publication of the 2021 PROSPECT guidelines for total hip arthroplasty, new evidence, particularly on motor‐sparing regional techniques, has ...
Michele Carella, Dario Bugada, Marc Van de Velde, Helene Beloeil, Eric Albrecht, Patricia Lavandhomme, Johan Raeder, Girish P. Joshi, on behalf of the PROSPECT Working Group of the European Society of Regional Anesthesia and Pain Therapy   +8 more
wiley   +1 more source

Burden of chronic postsurgical pain after caesarean delivery on maternal quality of life: a systematic review

Anaesthesia, EarlyView.
Summary Introduction Chronic postsurgical pain after caesarean delivery is an important cause of postpartum morbidity, yet its impact on maternal quality of life has not been comprehensively synthesised. The aims of this systematic review were to evaluate the impact of chronic postsurgical pain on quality of life, including possible temporal changes in
Samira Alwahabi, Rebekah Reville Joy, Payton Marshall, Lindsay Blake, Brendan Carvalho, Pervez Sultan, Sarah Ciechanowicz   +6 more
wiley   +1 more source

Intrathecal baclofen [PDF]

Developmental Medicine & Child Neurology, 2010
openaire   +2 more sources

Infiltration between the popliteal artery and the capsule of the knee (IPACK) vs. selective tibial nerve block for analgesia after total knee arthroplasty: a triple‐blinded randomised controlled trial

Anaesthesia, EarlyView.
Summary Introduction Infiltration between the popliteal artery and the capsule of the knee (IPACK) and the selective tibial nerve block provide analgesia for the posterior aspect of the knee after total knee arthroplasty. This randomised controlled triple‐blinded trial tested the hypothesis that IPACK provides superior analgesia to selective tibial ...
Marta Szyszko, Julien Wegrzyn, Jean‐Benoit Rossel, Alexandre Koninckx, Marine Pirot, Eric Albrecht   +5 more
wiley   +1 more source

Canadian evidence‐based guidelines on spinal procedures for chronic pain

Anaesthesia, EarlyView.
Summary Introduction Interventional procedures are commonly used to diagnose and treat chronic pain of spinal origin but guidance on: their indications; frequency; technical conduct; requirements for image guidance; outcome measurement; and management of complications is lacking.
Anuj Bhatia, Philip Peng, Harsha Shanthanna, Yasmine Hoydonckx, James S. Khan, Elad Dana, Abeer Alomari, Tarvit Worravitudomsuk, Howard Meng, Martina Rekatsina, Ian Gilron, Andrea D. Furlan, Norman Buckley, Ian Beauprie, Roderick Finlayson, Paul Etheridge, Eldon Loh, Christopher Mares, Mohan Radhakrishna, Sebastian Mafeld, John X. Pereira, Hance Clarke, Shawn Marshall, Magali Robert, Pam Squire, Robert Tanguay, Danielle Alvares   +26 more
wiley   +1 more source

INTRATHECAL BUPIVACAINE

British Journal of Anaesthesia, 1982
openaire   +2 more sources

The Clinical Research Landscape of Intracranial Nicardipine for Aneurysmal Subarachnoid Hemorrhage: Insights From Bibliometric Analysis

Drug Design, Development and Therapy
Guangtang Chen,1,* Yi Cao,1,2,* Xiaolin Du,3,* Junshuan Cui,1 Xi Zeng,1 Hua Yang,1 Zeguang Ren,1 Kaya Xu1 1Department of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China; 2School of ...
Chen G, Cao Y, Du X, Cui J, Zeng X, Yang H, Ren Z, Xu K   +7 more
doaj  

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source