Flexor Reflex Decreases during Sympathetic Stimulation in Chronic Human Spinal Cord Injury [PDF]
, 2009 A better understanding of autonomic influence on motor reflex pathways in spinal cord injury is important to the clinical management of autonomic dysreflexia and spasticity in spinal cord injured patients.
Garrison, Mark Kevin, Schmit, Brian D.
core +2 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Practice in anestHesia: intratHecal MorPHine for off PuMP coronary artery byPass graft
Journal of Nepal Medical Association, 2006 Pump. Address for correspondence : Dr. Bishwas Pradhan Institute of Medicine, TU Teaching Hospital, Maharajgunj, Kathmandu, Nepal Email: biswaspradhan@yahoo.com Received Date : 12th Aug, 2005 Accepted Date : 18th May, 2006 CaSE rEPort J Nep Med assoc ...
Bishwas Pradhan, B D Jha
doaj +1 more source
Intrathecal Administration of Morphine Decreases Persistent Pain after Cesarean Section: A Prospective Observational Study. [PDF]
PLoS ONE, 2016 PURPOSE:Chronic pain after cesarean section (CS) is a serious concern, as it can result in functional disability. We evaluated the prevalence of chronic pain after CS prospectively at a single institution in Japan.
Kumi Moriyama +5 more
doaj +1 more source
Specific down-regulation of spinal μ-opioid receptor and reduced analgesic effects of morphine in mice with postherpetic pain [PDF]
, 2006 The analgesic effects of opioid agonists and the expression of μ-and κ-opioid receptors were compared between mice with herpetic pain and those with postherpetic pain induced by herpetic virus inoculation.
Kuraishi Yasushi +3 more
core +2 more sources
Advanced Science, Volume 13, Issue 1, 5 January 2026.Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan +9 more
wiley +1 more source
Continuous intrathecal morphine infusion for pain management in a patient with burn injury
Burns Open, 2018 Introduction: Known risk factors for delirium include admission to an intensive care setting and administration of intravenous infusions for pain and sedation.
Alyssa R. Zuehl +3 more
doaj +1 more source
Comprehensive Systematic Review of long-term opioids in women with chronic non cancer pain and associated reproductive dysfunction (hypothalmic-pituitary-gonadal axis disruption) [PDF]
, 2016 A comprehensive systematic literature review of reproductive side effects in women aged 18 to 55 years treated with opioids for 1 month or longer for chronic noncancer pain.
Bedson, J +4 more
core +1 more source
Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei +11 more
wiley +1 more source
Super analgesia of intrathecal morphine may be related to ABCB1 (MDR1) gene polymorphism
Journal of Pain Research, 2018 Wangjun Qin,1,* Botao Liu,2,* Ang Deng,1 Ying Liu,1 Xianglin Zhang,1 Lei Zhang1 1Department of Pharmacy, China-Japan Friendship Hospital, Beijing, China; 2Department of Pain Management, China-Japan Friendship Hospital, Beijing, China *These authors ...
Qin WJ +5 more
doaj