Results 71 to 80 of about 58,052 (292)

Esophageal misplacement of a single-lumen tube after its exchange for a double-lumen tube despite the use of an airway-exchange catheter

open access: yesSaudi Journal of Anaesthesia, 2013
An airway-exchange catheter (AEC) can increase the safety of exchanges of endotracheal tubes (ETTs); however, the procedure is associated with potential risks.
Sung Mi Hwang   +3 more
doaj   +1 more source

Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle [PDF]

open access: yes, 2006
Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that is increasing in incidence in United Kingdom cattle herds. In addition to increasing economic losses, the rise in bovine tuberculosis poses a human health risk. There is an
Hope, J C, Howard, C J, Sopp, P
core   +2 more sources

Succinic Acid‐Induced Macrophage Endocytosis Promotes Extracellular Vesicle‐Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis‐Associated Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
Lipopolysaccharide (LPS) stimulates the production of succinic acid in lung tissue, which promotes macrophages endocytosis and the formation of multivesicular bodies (MVBs). These MVBs release profibrotic extracellular vesicles (EVs), facilitating the transfer of integrin beta1 (ITGβ1) transfer and subsequently activating fibroblasts, thereby ...
Wenyu Yang   +10 more
wiley   +1 more source

Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]

open access: yes, 2019
Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR   +8 more
core   +1 more source

Novel Evolutionarily Conserved Oncogene COA4 is Driven by KRAS Mutant and Promotes Cancer Metastasis Through Dual Mitochondrial Metabolism‐Dependent and ‐Independent Mechanisms

open access: yesAdvanced Science, EarlyView.
In KRAS‐mutant tumors, KRAS transcriptionally upregulates COA4 via the PI3K/AKT/E2F1 axis, promoting metastasis. Mechanistically, COA4 enhances tumor cell migration through dual pathways: within mitochondria, it boosts oxidative phosphorylation; in the cytoplasm, it binds and activates CDC42 to stimulate pseudopodia formation.
Xingzhao Ji   +14 more
wiley   +1 more source

The incidence of difficult intubation in 2 000 patients undergoing thyroid surgery: A single center experience [PDF]

open access: yesVojnosanitetski Pregled, 2009
Background/Aim. The incidence of difficult intubation (DI) is 1-10%, and DI leading to inability to intubate occurs in 0.04% of the population.
Kalezić Nevena   +7 more
doaj   +1 more source

Effective antiprotease-antibiotic treatment of experimental anthrax [PDF]

open access: yes, 2005
BACKGROUND: Inhalation anthrax is characterized by a systemic spread of the challenge agent, Bacillus anthracis. It causes severe damage, including multiple hemorrhagic lesions, to host tissues and organs.
Alibek, Ken   +8 more
core   +3 more sources

Intratracheal thyroid ‐ familial occurrence [PDF]

open access: yesThe Laryngoscope, 1985
AbstractThe presence of thryoid tissue within the tracheal lumen is an unusual cause of upper respiratory obstruction. Thyroid tissue in this location may represent true ectopic thyroid or may be caused by invnsion of the trachea by a malignant process.This paper presents two patients from the same family who were found to have thyroid tissue in the ...
F.R.C.S.I. J. Oliver Donegan M.D.   +1 more
openaire   +3 more sources

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

open access: yesAdvanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang   +14 more
wiley   +1 more source

مطالعه هیستوپاتولوژیکی ویروس آنفلوانزای تلقیح شده داخل نای (H9N2) در جوجه‌های مرغ [PDF]

open access: yesArchives of Razi Institute, 2004
The type, severity and frequency of gross lesion, histopatholgic change, and tissue tropism of A/Chicken/Iran/259/1998(H9N2) avian influenza virus following intratrachealy (IT) inoculation were studied in chickens.
سیدعلی پوربخش   +3 more
doaj   +1 more source

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