Results 71 to 80 of about 35,236 (241)

AN APPARATUS FOR INTRATRACHEAL INSUFFLATION

Annals of Surgery, 1912
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openaire   +4 more sources

Mechanistic Insights and Pharmacological Approaches for Nitrogen and Sulfur Mustards and Their Implications as Therapeutic Agents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nitrogen and sulfur mustards, often acting as vesicants, have significant consequences for public health. Skin is a common site for exposure to these vesicants that can result in considerable morbidity and mortality. Given that the treatment options are limited, new insights into the mechanisms for the toxicity of these vesicants that can be ...
Madison Owens, Anita Thyagarajan, Jeffrey B. Travers, Ravi P. Sahu   +3 more
wiley   +1 more source

Utilization of Ciprofloxacin‐Dexamethasone in the Airway: A Scoping Review

The Laryngoscope, EarlyView.
Off‐label ciprofloxacin‐dexamethasone has been used for over two decades to improve outcomes following airway surgery. Therefore, this scoping review evaluates the current literature to understand the potential utility of ciprofloxacin‐dexamethasone after airway surgery. Ciprofloxacin‐dexamethasone was found to provide utility with minimal side effects
Cyrus W. Abrahamson, Abbey L. Landini, Jasmine Stewart, Krystal Madkins, James A. Burns, Andrew P. Stein, Jonathan P. Kuriakose   +6 more
wiley   +1 more source

Anesthetic challenges in leaking meningomyelocele repair in a neonate

Journal of Marine Medical Society, 2019
Meningomyelocele is a neural tube defect, which comprises of a saccular protrusion containing a neural placode bathed in cerebral spinal fluid. Arachnoid covers the surface of the sac and dura or skin is missing.
Vidhu Bhatnagar, S N Kulkarni, M D Muzammil   +2 more
doaj   +1 more source

Intratracheal Administration of Nanoplastics With Varying Surface Hydrophobicity Results in Coarsely Vacuolated Alveolar Macrophages, Transient Respiratory Inflammation, and Mild Collagen Deposition

Nano Select, EarlyView.
Nanoplastic hydrophobicity drives adverse effects in the lung. Single intratracheal administration of poly(vinyl acetate‐co‐alcohol) nanoplastics with varying surface hydrophobicity shows that the more hydrophobic nanoplastics increase prevalence of coarsely vacuolated alveolar macrophages, induce transient respiratory inflammation and mild collagen ...
Anna Babin Morgan, Yanira Riffo‐Vasquez, Aateka Bodhaniya, Stuart A. Jones, Ben Forbes, Kavitha Sunassee, Rafael T. M. de Rosales, Stephanie Wright, Clive Page, Lea Ann Dailey   +9 more
wiley   +1 more source

Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential

The Journal of Pathology, EarlyView.
Abstract Lung cancer is the leading cause of cancer‐related death globally. To better understand the biology of lung cancer, mouse models have been developed using either tail vein‐injected tumour cell lines or genetically modified mice. The current gold‐standard models typically present with multiple lung foci.
Ana‐Rita Pedrosa, Alejandro Castillo‐Kauil, Yuliia Kravchuk, Louise Reynolds, Bruce Williams, David Moore, Cameron Lang, Srinivas Allanki, Eleni Maniati, Alexandros Hardas, Jozafina Haj, Rebecca Drake, Julie Cleaver, Julie Foster, Jana Kim, Ester Stern, Jane Sosabowski, Gilbert O. Fruhwirth, Erik Sahai, Ori Wald, Kairbaan Hodivala‐Dilke   +20 more
wiley   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

A prospective observational study of predictors of difficult intubation in Indian patients

Journal of Anaesthesiology Clinical Pharmacology, 2019
Background and Aims: During routine preoperative assessment of patients one of the commonest practices is predicting difficulty of intubation. The present study was undertaken to evaluate parameters associated with difficult intubation and to test on new
Harsha H Narkhede, Rajendra D Patel, Hemraj R Narkhede   +2 more
doaj   +1 more source

Forging a New Frontier: Antimicrobial Peptides and Nanotechnology Converging to Conquer Gastrointestinal Pathogens

Small, EarlyView.
This review explores the potential of antimicrobial peptides (AMPs) and nanotechnology for the treatment of gastrointestinal infections. It analyzes bacterial resistance mechanisms, the antimicrobial actions of AMPs, and advances in nanocarriers, such as lipid‐based, polymeric, metallic, and mesoporous silica systems, that enhance peptide protection ...
Christian Shleider Carnero Canales, Cesar Augusto Roque‐Borda, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Uner Josseph Pinto Apaza, Vanderson de Jesus Silva, Laura Maria Duran Gleriani Primo, Maura Jennifer Martínez‐Morales, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +10 more
wiley   +1 more source

Challenges Associated with the Pulmonary Delivery of Therapeutic Dry Powders for Preclinical Testing

KONA Powder and Particle Journal, 2018
Significant progress has been made over the last half-century in delivering therapeutics by the pulmonary route. Inhaled therapeutics are administered to humans using metered-dose inhalers, nebulizers, or dry powder inhalers, and each device requires a ...
Dominique N. Price, Nitesh K. Kunda, Pavan Muttil   +2 more
doaj   +1 more source