Results 81 to 90 of about 77,359 (282)

Pulmonary‐Targeted Nanoparticles Interrupt the Malignant Mechanical and Biochemical Signaling Crosstalk for Idiopathic Pulmonary Fibrosis Therapy

Advanced Science, EarlyView.
Idiopathic pulmonary fibrosis (IPF) progression is driven by TGF‐β induced biochemical signals and mechanical signals from increased ECM stiffness. Pulmonary‐targeted VB‐RT NPs not only eliminate excessive ROS and penetrate the dense ECM collagen barrier via NO release, but also simultaneously interrupt the persistent malignant between mechanical and ...
Xue‐Na Li, Ya‐Ping Lin, Xi‐Xi Ma, Yue‐Fei Fang, Hui Wang, Chun‐Hui Cui, Chen Zhang, Jin‐You Piao, Jee‐Heon Jeong, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +11 more
wiley   +1 more source

Esophageal misplacement of a single-lumen tube after its exchange for a double-lumen tube despite the use of an airway-exchange catheter

Saudi Journal of Anaesthesia, 2013
An airway-exchange catheter (AEC) can increase the safety of exchanges of endotracheal tubes (ETTs); however, the procedure is associated with potential risks.
Sung Mi Hwang, Jae Jun Lee, Ji Su Jang, Nak Hun Lee   +3 more
doaj   +1 more source

Establishment of a mouse model for pulmonary inflammation and fibrosis by intratracheal instillation of polyhexamethyleneguanidine phosphate

Journal of Toxicologic Pathology, 2016
Although several animal models have been developed to study human pulmonary fibrosis, lack of a perfect model has raised the need for various animal models of pulmonary fibrosis.
S. Lee, Jong-Hwan Park, Jun-young Lee, Yu-Jin Jeong, Jeongah Song, Kyuhong Lee, Dong‐Jae Kim   +6 more
semanticscholar   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

Advanced Science, EarlyView.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna, Jinshan He, Jiaxing Miao, Nargis Shaheen, Boyu Xia, Cankun Wang, Qin Ma, Matthew C Bernier, Bryan A Whitson, Nuo Sun, Jing Zhao, Yutong Zhao   +11 more
wiley   +1 more source

Effective antiprotease-antibiotic treatment of experimental anthrax [PDF]

, 2005
BACKGROUND: Inhalation anthrax is characterized by a systemic spread of the challenge agent, Bacillus anthracis. It causes severe damage, including multiple hemorrhagic lesions, to host tissues and organs.
Alibek, Ken, Bailey, Charles, Chandhoke, Vikas, Fryxell, Karl J, Hopkins, Svetlana, MacAfee, Rebecca, Popov, Serguei G, Popova, Taissia G, Weinstein, Raymond S   +8 more
core   +3 more sources

Comparison of single or multiple intratracheal administration for pulmonary toxic responses of nickel oxide nanoparticles in rats

Journal of Occupational Health, 2016
In this study, we focused on the qualitative and quantitative differences of the lung lesions induced by single or multiple intratracheal administration of nickel oxide nanoparticles (NiO).
Hideki Senoh, H. Kano, Masaaki Suzuki, M. Ohnishi, H. Kondo, Kenji Takanobu, Yumi Umeda, S. Aiso, S. Fukushima   +8 more
semanticscholar   +1 more source

Prolonged Prophylactic Antibiotics Based on Preoperative Bile Culture Reduce Surgical Site Infections After Pancreaticoduodenectomy Following Preoperative Biliary Drainage: A Propensity‐Matched Analysis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Objective The optimum duration of prophylactic antibiotics after pancreaticoduodenectomy following preoperative biliary drainage to prevent surgical site infections remains controversial. We evaluate whether a prolonged course of prophylactic antibiotics reduces surgical site infection after pancreaticoduodenectomy following biliary drainage ...
Kyohei Matsumoto, Atsushi Shimizu, Yuji Kitahata, Akihiro Takeuchi, Hideki Motobayashi, Masatoshi Sato, Tomohiro Yoshimura, Shinya Hayami, Atsushi Miyamoto, Manabu Kawai   +9 more
wiley   +1 more source

The incidence of difficult intubation in 2 000 patients undergoing thyroid surgery: A single center experience [PDF]

Vojnosanitetski Pregled, 2009
Background/Aim. The incidence of difficult intubation (DI) is 1-10%, and DI leading to inability to intubate occurs in 0.04% of the population.
Kalezić Nevena, Milosavljević Radoje, Paunović Ivan, Živaljević Vladan, Diklić Aleksandar, Matić Danica, Ivanović Branislava, Nešković Vojislava   +7 more
doaj   +1 more source

Early administration of surfactant via a thin intratracheal catheter in preterm infants with respiratory distress syndrome: Feasibility and outcome

Journal of Research in Pharmacy Practice, 2015
Objective: Currently, the method of early nasal continuous positive airway pressure (nCPAP) and selective administration of surfactant via an endotracheal tube is widely used in the treatment of respiratory distress syndrome (RDS) in premature infants ...
Majid Mohammadizadeh, A. Ardestani, A. Sadeghnia   +2 more
semanticscholar   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

Animal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang, Siman Sun, Xiaoyu Fan, Jiuming He, Qing Li, Hongtao Jin   +5 more
wiley   +1 more source