Results 91 to 100 of about 53,924 (268)

Clinical benefit of adenosine as an adjunct to reperfusion in ST-elevation myocardial infarction patients: An updated meta-analysis of randomized controlled trials [PDF]

, 2015
Background: Adenosine administered as an adjunct to reperfusion can reduce coronary no-reflow and limit myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients. Whether adjunctive adenosine therapy can improve clinical
Bulluck, Heerajnarain, Garcia-Dorado, David, Hausenloy, Derek J., Loke, Yoon K., Sirker, Alex, Universitat Autònoma de Barcelona   +5 more
core   +2 more sources

Nomogram for Deep Vein Thrombosis Prediction Post‐Endovascular Thrombectomy in Acute Ischemic Stroke: A Retrospective Multicenter Observational Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Background Deep vein thrombosis (DVT) is a frequent complication following endovascular thrombectomy (EVT) in patients with acute ischaemic stroke (AIS), potentially leading to fatal pulmonary embolism (PE). Identifying patients early at high risk for DVT is clinically important.
Li Han, Teng‐Wei Pan, Li‐Li Yang, Wei‐Yang Qian, Xiao‐Ping Xu, Feng Wang, Wei‐Zhen Wang, Yang Liu, Wei‐Ying Yang   +8 more
wiley   +1 more source

Recanalization treatment for acute ischemic stroke: 3-month outcome before and after implementation of routine endovascular treatment

eNeurologicalSci, 2022
Background and purpose: Endovascular treatment for acute ischemic stroke has become a recommended treatment option for selected patients after several randomized controlled trials have shown the effectiveness of endovascular treatment.
Kati Valkonen, Nicolas Martinez-Majander, Gerli Sibolt, Marjaana Tiainen, Silja Räty, Tatu Kokkonen, Kimmo Lappalainen, Sami Curtze   +7 more
doaj  

Fatal Outcome of Intravenous Thrombolysis With an Unexpected Finding of Amyloid‐β‐Related Angiitis—A Case Report Highlighting a Relevant Scenario With Acute Focal Neurological Deficits and Minimal Radiological Presentation

Neuropathology, EarlyView.
ABSTRACT Cerebral amyloid angiopathy (CAA) has been implicated as a risk for developing lobar intracerebral hemorrhage (ICH) after intravenous thrombolysis (IVT) applied for acute ischemic stroke (AIS). However, there is a paucity of cases reported with histopathological CAA diagnosis in this setting, with a single report to imply the role of CAA ...
Kristof Babarczy, Bence L. Radics, Orsolya Horvath, Peter Klivenyi, Levente Szalardy   +4 more
wiley   +1 more source

Effects Of Attenuation And Thrombus Age On The Success Of Ultrasound And Microbubble-Mediated Thrombus Dissolution [PDF]

, 2011
The purpose of this study was to examine the effects of applied mechanical index, incident angle, attenuation and thrombus age on the ability of 2-D vs. 3-D diagnostic ultrasound and microbubbles to dissolve thrombi.
Drvol, L. K., Everbach, E. Carr, Gao, S. J., Lof, J., Porter, T. R., Powers, J. E., Shi, W. T., Vignon, F., Xie, F.   +8 more
core   +3 more sources

Health and economic benefits of improving pre‐hospital identification of stroke in Australian women: a modelling study

Medical Journal of Australia, EarlyView.
Abstract Objective To estimate the long term gains in life years and quality‐adjusted life years (QALYs) and the cost savings that could be achieved if ischaemic stroke was identified in women with the same level of accuracy received by men, versus the status quo. Design Decision tree and Markov model decision analysis.
Thomas Gadsden, Lei Si, Emily R Atkins, Cheryl Carcel, Xia Wang, Stephen Jan, Mark Woodward, Laura E Downey   +7 more
wiley   +1 more source

Using Tenecteplase for Acute Ischemic Stroke: What Is the Hold Up? [PDF]

, 2020
Alteplase is the only Food and Drug Administration-approved intravenous (IV) thrombolytic medication for acute ischemic stroke. However, multiple recent studies comparing tenecteplase and alteplase suggest that tenecteplase is at least as efficacious as ...
Ataya, Ramsey, Brea, Isabel, Zitek, Tony
core  

Neuroimaging as a selection tool and endpoint in preclinical and clinical trials [PDF]

, 2016
Standard imaging in acute stroke enables the exclusion of non-stroke structural CNS lesions and cerebral haemorrhage from clinical and pre-clinical ischaemic stroke trials. In this review, the potential benefit of imaging (e.g., angiography and penumbral
Macrae, I. Mhairi, Muir, Keith W.
core   +2 more sources

Tracking Hyperpolarized [1‐13C] Pyruvate and [1‐13C] L‐Lactate Metabolism in the Healthy and Post‐Stroke Mouse Brain

NMR in Biomedicine, Volume 38, Issue 8, August 2025.
Hyperpolarized [1‐13C] pyruvate and [1‐13C] lactate provide complementary views on the same metabolic pathways. We investigated their performance as cerebral metabolic contrast agents in healthy mice and mice subjected to transient ischemia. We found that the cerebral metabolism of both substrates was significantly altered after ischemia and discuss ...
Thanh Phong Lê, Lara Buscemi, Mario Lepore, Elise Vinckenbosch, Bernard Lanz, Rolf Gruetter, Lorenz Hirt, Jean‐Noël Hyacinthe, Mor Mishkovsky   +8 more
wiley   +1 more source

急性缺血性卒中静脉溶栓桥接血管内治疗的疗效和安全性 Efficacy and Safety of Intravenous Thrombolysis Bridging Endovascular Therapy for Acute Ischemic Stroke

Zhongguo cuzhong zazhi, 2019
目的 观察rt-PA静脉溶栓桥接血管内治疗急性缺血性卒中的临床疗效和安全性。 方法 回顾性纳入2017年1-12月郑州市第一人民医院神经重症科收治的前循环急性缺血性卒中患 者，按rt-PA静脉溶栓后是否桥接血管内治疗分为单纯静脉溶栓组和桥接治疗组。主要疗效结局为治 疗后3个月mRS评分，次要疗效结局为24 h、3 d和30 d的NI HSS评分。安全性结局为2 d症状性颅内出血及 其他部位出血、10 d全因死亡。 结果 共入组56例患者，平均年龄60.77±12.72岁，男性35例（62.5 ...
乐婷，娄萍，路青山
doaj   +1 more source