Results 91 to 100 of about 700,178 (349)

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Pharmaco – Mechanical management of acute massive pulmonary embolism in a postpartum female

Indian Heart Journal, 2014
Background: The optimal use of pharmaco-mechanical therapy is not clear in the management of the acute massive pulmonary thromboembolism. Methods: A 30-year-old postpartum female presented with acute massive pulmonary embolism and was managed with ...
Sandeep Goel, Ranjit Nath, Neeraj Pandit
doaj   +1 more source

Dynamic Decrease in Eosinophil After Intravenous Thrombolysis Predicts Poor Prognosis of Acute Ischemic Stroke: A Longitudinal Study

Frontiers in Immunology, 2021
Background and PurposeBlood eosinophil counts are thought to be associated with atherosclerosis in acute ischemic stroke (AIS) and AIS severity. We aimed to investigate 1): the temporal profile of eosinophil in AIS patients treated with recombinant ...
Dehao Yang, Honghao Huang, Honghao Huang, Yiyun Weng, Junli Ren, Junli Ren, Chenguang Yang, Chenguang Yang, Jianing Wang, Jianing Wang, Beibei Gao, Tian Zeng, Tian Zeng, Jingyu Hu, Jingyu Hu, Wenjing Pan, Wenjing Pan, Fangyue Sun, Fangyue Sun, Xinbo Zhou, Xinbo Zhou, Guangyong Chen   +21 more
doaj   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Safety of thrombolysis in acute ischemic stroke patients with previous aortic abdominal aneurysm repair

Journal of Stroke and Cerebrovascular Diseases
Objective: Intravenous thrombolysis is the standard treatment for acute ischemic stroke (AIS), but its safety in patients with a history of abdominal aortic aneurysm (AAA) repair remains unclear.
Walter Duarte-Celada, MD, Katherine Rivas, MD, Pichatorn Suppakitjanusant, MD, Pamela Davila-Siliezar, MD, Myriam Vijil, MD, Ximena Gamboa, MD, Chanaka N. Kahathuduwa, MD, PhD, Riichi Ota, MD, Ross Raedeke, Darko Quispe-Orozco, MD   +9 more
doaj   +1 more source

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila, Eskandani, Morteza, Farhoudi, Mehdi, Mohammadian, Reza, Rafi, Mohammad, Zamanlu, Masumeh   +5 more
core   +2 more sources

P11.69.B INTRAVENOUS THROMBOLYSIS WITH OR WITHOUT ENDOVASCULAR TREATMENT FOR SUSPECTED ISCHEMIC STROKE IN PATIENTS WITH INTRACRANIAL TUMORS [PDF]

, 2023
Katharina Seystahl, Nicolas Martinez‐Majander, Alexander Salerno, Boris Modrau, Hebun Erdur, João Pedro Marto, Christian Hametner, Marialuisa Zedde, Alessandro Pezzini, Ronen R. Leker, Valerian Altersberger, Guido Costamagna, Miguel Serôdio, Ludovica Migliaccio, Rosario Pascarella, Andrea Zini, L Razaqi, Yannick Béjot, Simon Jung, Henrik Gensicke, Višnja Padjen, Peter A. Ringleb, Christian H. Nolte, Mirjam R. Heldner, Patrik Michel, Stefan T. Engelter, Susanne Wegener, Michael Weller   +27 more
openalex   +1 more source

Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation

Advanced Materials, EarlyView.
Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju, Roshan Velluvakandy, Xianghua Wu, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Kamila Bendíčková, Jan Frič, Martin Pumera   +7 more
wiley   +1 more source

Intravenous Thrombolysis in Patients on Direct Oral Anticoagulants: Analysis of the Get With The Guidelines Stroke Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Intravenous thrombolysis for acute ischemic stroke (AIS) is a proven effective treatment. Whether thrombolysis in patients with AIS with recent direct oral anticoagulant (DOAC) use is safe and efficacious is not well established.
Shadi Yaghi, Liqi Shu, Eva A. Mistry, Opeolu Adeoye, Lee Schwamm, Steven Messe, Mitchell S. V. Elkind, Malik Ghannam, Adam de Havenon, Karen Furie, Ying Xian, Christopher Streib, Runqi Wangqin, Nils Henninger, Jeffrey L. Saver, Eric E. Smith   +15 more
doaj   +1 more source

Statin Use and Outcomes of Patients With Acute Ischemic Stroke Treated With Intravenous Thrombolysis: A Systematic Review and Meta-Analysis [PDF]

, 2021
Yu Guo, Xin-Mei Guo, Kai Zhao, Qiangji Bao, Jincai Yang, Mingfei Yang   +5 more
openalex   +1 more source