Results 21 to 30 of about 58,078 (149)

Vitamin C Intervention for Critical COVID-19: A Pragmatic Review of the Current Level of Evidence

Life, 2021
Severe respiratory infections are characterized by elevated inflammation and generation of reactive oxygen species (ROS) which may lead to a decrease in antioxidants such as vitamin C and a higher requirement for the vitamin.
Patrick Holford, Anitra C. Carr, Masuma Zawari, Marcela P. Vizcaychipi   +3 more
doaj   +1 more source

Chemical reactions of vitamin C with intravenous-iron formulations [PDF]

Nephrology Dialysis Transplantation, 2007
Intravenous (IV) iron is widely prescribed for patients on haemodialysis, to replace iron losses during treatment. It releases labile iron, which can induce oxidation of vitamin C and trigger oxidant damage. We examined the stability of vitamin C in the presence of IV iron compounds.
Suxin, Wang, Gina, Geraci, Martin K, Kuhlmann, Nathan W, Levin, Garry J, Handelman   +4 more
openaire   +2 more sources

Intravenously administered vitamin C as cancer therapy: three cases [PDF]

Canadian Medical Association Journal, 2006
Early clinical studies showed that high-dose vitamin C, given by intravenous and oral routes, may improve symptoms and prolong life in patients with terminal cancer. Double-blind placebo-controlled studies of oral vitamin C therapy showed no benefit.
Sebastian J, Padayatty, Hugh D, Riordan, Stephen M, Hewitt, Arie, Katz, L John, Hoffer, Mark, Levine   +5 more
openaire   +2 more sources

Treatment of pancreatic cancer with intravenous vitamin C [PDF]

Anti-Cancer Drugs, 2018
Pancreatic ductal adenocarcinoma (PDA) has a dismal prognosis and is often discovered at an advanced stage with few therapeutic options. Current conventional regimens for PDA are associated with significant morbidity, decreased quality of life, and a considerable financial burden.
Drisko, Jeanne A., Serrano, Oscar K., Spruce, Lisa R., Chen, Qi, Levine, Mark   +4 more
openaire   +2 more sources

Early high-dose vitamin C in post-cardiac arrest syndrome (VITaCCA): study protocol for a randomized, double-blind, multi-center, placebo-controlled trial

Trials, 2021
Background High-dose intravenous vitamin C directly scavenges and decreases the production of harmful reactive oxygen species (ROS) generated during ischemia/reperfusion after a cardiac arrest.
Sander Rozemeijer, Harm-Jan de Grooth, Paul W. G. Elbers, Armand R. J. Girbes, Corstiaan A. den Uil, Eric A. Dubois, Evert-Jan Wils, Thijs C. D. Rettig, Arthur R. H. van Zanten, Roel Vink, Bas van den Bogaard, Rob J. Bosman, Heleen M. Oudemans-van Straaten, Angélique M. E. de Man   +13 more
doaj   +1 more source

Ascorbic acid concentrations in aqueous humor after systemic vitamin C supplementation in patients with cataract: pilot study

BMC Ophthalmology, 2017
Background To measure ascorbic acid concentration in aqueous humor of patients with cataract after oral or intravenous vitamin C supplementation. Methods Forty-two eyes of 42 patients with senile cataract who underwent uncomplicated cataract surgery were
Young-Sool Hah, Hye Jin Chung, Sneha B. Sontakke, In-Young Chung, Sunmi Ju, Seong-Wook Seo, Ji-Myong Yoo, Seong-Jae Kim   +7 more
doaj   +1 more source

Evaluation of the effect of high dose intravenous vitamin C on delayed allograft function in deceased donor kidney transplantation: a preliminary report

Renal Replacement Therapy, 2020
Background Delayed graft function (DGF) can affect short- and long-term allograft outcomes in kidney transplant recipients. One of the pathophysiological pathways in the occurrence of DGF is ischemia-reperfusion injury (IRI).
Mina Borran, Simin Dashti-Khavidaki, Azam Alamdari, Neda Naderi, Farzanehsadat Minoo   +4 more
doaj   +1 more source

No significant benefit of moderate-dose vitamin C on severe COVID-19 cases

Open Medicine, 2021
There is no specific drug for coronavirus disease 2019 (COVID-19). We aimed to investigate the possible clinical efficacy of moderate-dose vitamin C infusion among inpatients with severe COVID-19.
Zheng Shaoping, Chen Qiaosen, Jiang Hongbo, Guo Chunxia, Luo Jinzhuo, Li Sumeng, Wang Hua, Li Huadong, Zheng Xin, Weng Zhihong   +9 more
doaj   +1 more source

Liposomal-encapsulated Ascorbic Acid: Influence on Vitamin C Bioavailability and Capacity to Protect against Ischemia–Reperfusion Injury

Nutrition and Metabolic Insights, 2016
Intravenous administration of vitamin C has been shown to decrease oxidative stress and, in some instances, improve physiological function in adult humans.
Janelle L. Davis, Hunter L. Paris, Joseph W. Beals, Scott E. Binns, Gregory R. Giordano, Rebecca L. Scalzo, Melani M. Schweder, Emek Blair, Christopher Bell   +8 more
doaj   +1 more source

Intravenous Vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial

Nutrition Journal, 2012
Background Studies of the efficacy of vitamin C treatment for fatigue have yielded inconsistent results. One of the reasons for this inconsistency could be the difference in delivery routes. Therefore, we planned a clinical trial with intravenous vitamin
Suh Sang-Yeon, Bae Woo, Ahn Hong-Yup, Choi Sung-Eun, Jung Gyou-Chul, Yeom Chang   +5 more
doaj   +1 more source