Results 41 to 50 of about 19,735 (258)
Intrinsic Reward Policy Optimization for Sparse-Reward Environments
CoRRExploration is essential in reinforcement learning as an agent relies on trial and error to learn an optimal policy. However, when rewards are sparse, naive exploration strategies, like noise injection, are often insufficient. Intrinsic rewards can also provide principled guidance for exploration by, for example, combining them with extrinsic rewards ...
Minjae Cho, Huy Trong Tran
openaire +2 more sources
An Affect Misattribution Pathway to Perceptions of Intrinsic Reward [PDF]
Social Cognition, 2017 Intrinsic rewards are typically thought to stem from an activity's inherent properties and not from separable rewards one receives from it. Yet, people may not consciously notice or remember all the subtle external rewards that correspond with an activity and may misattribute some directly to the activity itself.
Leander, N. Pontus +3 more
openaire +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Endogenous opioids facilitate intrinsically-rewarded birdsong [PDF]
Scientific Reports, 2020 AbstractMany songbirds sing in non-reproductive contexts while in flocks. Singing in such gregarious contexts is critical for maintaining and learning songs; however, song is not directed towards other individuals and has no obvious, immediate social consequences.
Stevenson, Sharon A. +6 more
openaire +2 more sources
Frontiers in Psychology, 2019 Despite the vast amount of research focusing on intrinsic and extrinsic motivation, the effects of extrinsic motivators on creativity and innovation have been scarcely investigated.
Carmen Fischer +2 more
doaj +1 more source
Frontiers in Psychology, 2021 Kindergarten teachers' engagement in work is influenced by many factors. Total rewards perceptions, as an individual's evaluation of the rewards provided by the organization, may promote work engagement when it can meet their intrinsic and extrinsic work
Dongying Ji, Li Cui
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
加薪是萬靈丹？ 桃園市國民小學教師兼任行政職務意願影響因素建構之研究 Is Increasing Salary a Panacea? A Study on the Factors Influencing Taoyuan City Elementary School Teachers’ Willingness to Assume Administrative Roles [PDF]
Shizi Peiyu Yu Jiaoshi Zhuanye Fazhan Qikan本研究旨在探討桃園市國民小學教師選擇兼任行政職務的影響因素。相關研究指出透過提升行政加給或增加福利，或可提升教師擔任行政職務意願。然而，這是否能有效解決人力不足問題，仍有待深入探討。本研究以文獻回顧為基礎，再與兩位專家修正後，建立家庭因素、個人因素、組織因素與薪資酬賞因素四個構面及11個向度，並採用層級分析法 (Analytic Hierarchy Process, AHP) 分析權重比例，並輔以半結構式訪談。獲致結論如下：一、影響兼任行政職意願的四個構面中，「家庭因素」最重要，其次為「個人因素」；二 ...
黃鈺容 Yu-Jung Huang +1 more
doaj +1 more source