Results 41 to 50 of about 29,703 (304)

PhosIDP: a web tool to visualize the location of phosphorylation sites in disordered regions

Scientific Reports, 2021
Charge is a key determinant of intrinsically disordered protein (IDP) and intrinsically disordered region (IDR) properties. IDPs and IDRs are enriched in sites of phosphorylation, which alters charge.
Sonia T. Nicolaou, Max Hebditch, Owen J. Jonathan, Chandra S. Verma, Jim Warwicker   +4 more
doaj   +1 more source

Functional analysis of the N‐terminal region of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis

FEBS Open Bio, 2022
Acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis (TTE0866) has an N‐terminal region (NTR; residues 23–135) between the signal sequence (residues 1–22) and the catalytic domain (residues 136–324), which is of unknown function ...
Kohei Sasamoto, Tomoki Himiyama, Kunihiko Moriyoshi, Takashi Ohmoto, Koichi Uegaki, Tsutomu Nakamura, Yoshiaki Nishiya   +6 more
doaj   +1 more source

Kinetic Methods of Deducing Binding Mechanisms Involving Intrinsically Disordered Proteins

, 2021
There are multiple examples of protein-protein interactions involving one intrinsically disordered protein region binding to an ordered protein domain in a coupled binding and folding reaction.
Elin Karlsson, Karlsson, Elin,, Per Jemth, Jemth, Per,   +3 more
core   +1 more source

Intrinsically disordered protein, DNA binding with one finger transcription factor (OsDOF27) implicates thermotolerance in yeast and rice

Frontiers in Plant Science, 2022
Intrinsically disorder regions or proteins (IDRs or IDPs) constitute a large subset of the eukaryotic proteome, which challenges the protein structure–function paradigm.
Nishu Gandass, Kajal, Prafull Salvi
doaj   +1 more source

DARUMA: a gateway to fast and easy prediction of intrinsically disordered regions [PDF]

PeerJ Computer Science
Background Intrinsically disordered proteins (IDPs) are proteins that contain intrinsically disordered regions (IDRs), which lack stable three-dimensional structures under physiological conditions.
Itsuki Shimizu, Takuya Ida, Yuhei Ozawa, Satoshi Fukuchi, Hiroto Anbo   +4 more
doaj   +2 more sources

iLIR : a web resource for prediction of Atg8-family interacting proteins [PDF]

, 2014
Macroautophagy was initially considered to be a nonselective process for bulk breakdown of cytosolic material. However, recent evidence points toward a selective mode of autophagy mediated by the so-called selective autophagy receptors (SARs).
Nezis, I. P., Osgood, Richard, Mulakkal, Nitha Charles, Promponas, Vasilis J., Kalvari, Ioanna, Johansen, Terje, Tsompanis, Stelios   +6 more
core   +1 more source

OPAL: prediction of MoRF regions in intrinsically disordered protein sequences [PDF]

Bioinformatics, 2018
AbstractMotivationIntrinsically disordered proteins lack stable 3-dimensional structure and play a crucial role in performing various biological functions. Key to their biological function are the molecular recognition features (MoRFs) located within long disordered regions. Computationally identifying these MoRFs from disordered protein sequences is a
Ronesh Sharma, Gaurav Raicar, Tatsuhiko Tsunoda, Ashwini Patil, Alok Sharma   +4 more
openaire   +3 more sources

Polycation-π Interactions Are a Driving Force for Molecular Recognition by an Intrinsically Disordered Oncoprotein Family

, 2013
Molecular recognition by intrinsically disordered proteins (IDPs) commonly involves specific localized contacts and target-induced disorder to order transitions.
Sheung Chun Ng, Ng Sheung Chun, Hue Sun Chan (135066), Chan, Hue Sun, Song Jianhui, Song, Jianhui, Jianhui Song, Tompa, Péter, Lee Kevin A. W., Peter Tompa, Lee, Kevin Andrew William, Sheung Chun Ng (463510), Jianhui Song (463509), Tompa Peter, Hue Sun Chan, Peter Tompa (38445), Chan Hue Sun, Ng, Sheung Chun, Kevin A. W. Lee (7686), Kevin A W Lee   +19 more
core   +1 more source

Intrinsically disordered proteins and structured proteins with intrinsically disordered regions have different functional roles in the cell

PLOS ONE, 2019
Abstract Many studies about classification and the functional annotation of intrinsically disordered proteins (IDPs) are based on either the occurrence of long disordered regions or the fraction of disordered residues in the sequence.
Deiana, Antonio, Forcelloni, Sergio, Porrello, Alessandro, Giansanti, Andrea   +3 more
openaire   +4 more sources

The N-terminal intrinsically disordered domain of mgm101p is localized to the mitochondrial nucleoid.

, 2013
The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core ...
George Desmond Clark-Walker (281878), George Desmond Clark-Walker, Dosztányi Zsuzsanna, Zsuzsanna Dosztányi (57464), Clark-Walker, George Desmond, Zsuzsanna Dosztányi, Clark-Walker George Desmond, David C. Hayward (198611), David C. Hayward, Hayward David C., Hayward, David C., Dosztányi, Zsuzsanna, David C Hayward   +12 more
core   +1 more source