Results 141 to 150 of about 23,829 (240)

Characterisation of the effects of intrinsically disordered protein (IDP)-solvent and IDP-lipid interactions in aqueous solution and lipid monolayers

, 2019
In dieser Arbeit wurde das Aggregationsverhalten zweier verschiedener Arten intrinsisch unstrukturierter Proteine untersucht. Zum einen wurde der Temperatur-abhängige inverse Phasenübergang von thermoresponsiven Peptid-Polymeren als Funktion der Aminosäuresequenz mit Elektronenspinresonanz- Spektroskopie untersucht.
openaire   +2 more sources

Intrinsically Disordered Proteins

, 2013
Many biologically active proteins fail to form unique three-dimensional (3D) structures under physiological conditions, either along their entire lengths or locally. These proteins are known as intrinsically disordered proteins (IDPs) among several other
V.N. Uversky, Uversky, Vladimir N., Vladimir N. Uversky   +2 more
core   +1 more source

Intrinsically disordered proteins: regulation and disease.

, 2011
Item does not contain fulltextIntrinsically disordered proteins (IDPs) are enriched in signaling and regulatory functions because disordered segments permit interaction with several proteins and hence the re-use of the same protein in multiple pathways ...
Robin van der Lee, Lee, R.T.J.G. van der, Natalia Sanchez de Groot, Jörg Gsponer, Gsponer, J., M Madan Babu, Babu, M.M., Groot, N.S. de   +7 more
core   +1 more source

EPR in protein science : intrinsically disordered proteins

, 2011
Intrinsically disordered proteins (IDPs) form a unique protein category characterized by the absence of a well-defined structure and by remarkable conformational flexibility.
Drescher, Malte, Malte Drescher
core   +1 more source

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

BMC Genomics, 2009
Background Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) lack stable tertiary and/or secondary structure yet fulfills key biological functions.
Xue Bin, Xie Hongbo, Midic Uros, Oldfield Christopher J, Uversky Vladimir N, Vucetic Slobodan, Iakoucheva Lilia M, Obradovic Zoran, Dunker A Keith   +8 more
doaj   +1 more source

Martini3-IDP: improved Martini 3 force field for disordered proteins

Nature Communications
Coarse-grained (CG) molecular dynamics (MD) is widely used for the efficient simulation of intrinsically disordered proteins (IDPs). The Martini model, one of the most popular CG force fields in biomolecular simulation, was reported to yield too compact ...
Liguo Wang, Christopher Brasnett, Luís Borges-Araújo, Paulo C. T. Souza, Siewert J. Marrink   +4 more
semanticscholar   +1 more source

Intrinsically disordered proteins: Emerging interaction specialists

, 2015
Intrinsically disordered proteins or regions of proteins (IDPs/IDRs) most often function through protein-protein interactions, when they permanently or transiently bind partner molecules with diverse functional consequences.
Tantos, Ágnes, Kalmár, Lajos, Schád, Éva, Tompa, Péter   +3 more
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Intrinsically disordered proteins [PDF]

, 2016
Nativno neuređeni proteini i proteinske regije (​engl. intrinsically disordered proteins/regions, IDP/IDR) pripadaju nedavno priznatoj skupini proteina koji su biološki aktivni usprkos nedostatku jasno definirane trodimenzionalne strukture. Za razliku od
Tomljanović, Ingrid
core  

Computer Simulations of Intrinsically Disordered Proteins

, 2017
The investigation of intrinsically disordered proteins (IDPs) is a new frontier in structural and molecular biology that requires a new paradigm to connect structural disorder to function.
Sihyun Ham, Prathit Chatterjee, Song-Ho Chong   +2 more
core   +1 more source

Intrinsically disordered proteins in molecular recognition and structural proteomics

, 2014
Indiana University-Purdue University Indianapolis (IUPUI)Intrinsically disordered proteins (IDPs) are abundant in nature, being more prevalent in the proteomes of eukaryotes than those of bacteria or archaea.
Oldfield, Christopher John
core   +1 more source