Results 121 to 130 of about 1,763,945 (204)

Intrinsic Fluorescence of Intrinsically Disordered Proteins

, 2012
Resolution of the intrinsic emission properties of a protein by different fluorescence spectroscopy techniques is an invaluable tool to detect and characterize its structural architecture and conformational changes under different experimental conditions.
NEYROZ, PAOLO, Paolo Neyroz, Stefano Ciurli, CIURLI, STEFANO LUCIANO   +3 more
core   +1 more source

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

BMC Genomics, 2009
Background Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) lack stable tertiary and/or secondary structure yet fulfills key biological functions.
Xue Bin, Xie Hongbo, Midic Uros, Oldfield Christopher J, Uversky Vladimir N, Vucetic Slobodan, Iakoucheva Lilia M, Obradovic Zoran, Dunker A Keith   +8 more
doaj   +1 more source

Disordered proteins interact with the chemical environment to tune their protective function during drying

eLife
The conformational ensemble and function of intrinsically disordered proteins (IDPs) are sensitive to their solution environment. The inherent malleability of disordered proteins, combined with the exposure of their residues, accounts for this ...
Shraddha KC, Kenny H Nguyen, Vincent Nicholson, Annie Walgren, Tony Trent, Edith Gollub, Paulette Sofia Romero-Perez, Alex S Holehouse, Shahar Sukenik, Thomas C Boothby   +9 more
doaj   +1 more source

Structural analysis of intrinsically disordered proteins: computer atomistic simulation [PDF]

, 2016
Intrinsically disordered proteins (IDPs) are biomolecules that do not have a definite 3D structure; their role in the biochemical network of a cell relates to their ability to switch rapidly among different secondary and tertiary structures.
Ciasca, Gabriele, TENENBAUM, Alexander, Battisti, Anna   +2 more
core  

Programming cellular condensates for living materials using an intrinsically disordered protein display platform (iDP ² )

Abstract Self-organization of multicellular systems is vital for building structure in living system but remains underexplored in engineered living materials. We developed iDP 2 , a platform enabling high-density display of intrinsically disordered proteins on the surface of
Rong Chang, Hann Tu, Neel S. Joshi
openaire   +1 more source

Beyond the structure-function paradigm: A comprehensive review of intrinsically disordered proteins. [PDF]

Biochem Biophys Rep
Harake SNA, Btadini S, Qadri AH, Harb F, Faheem I.   +4 more
europepmc   +1 more source

INTRINSICALLY DISORDERED PROTEINS (IDPS) IN HUMAN DISEASES: A REVIEW

International Research Journal Of Pharmacy, 2018
openaire   +1 more source

Label-free optical observation of disordered-to-ordered transitions in single intrinsically disordered proteins. [PDF]

NPJ Biosens
Zargarbashi S, Dominguez C, Peters M, Yousefi A, Munday S, Wang Y, Chatterjee S, Hudson AJ, Gordon R, Mellor CJ, Xu L, Rahmani M, Ying C.   +12 more
europepmc   +2 more sources

Going high-throughput: Dynamic conformations and interactions <i>in vivo</i>. [PDF]

Magn Reson Lett
Gong Z, Zhao Q, Sun M, Zhang B, Zhang X, Zhang L, Zhang Y, Liu M.   +7 more
europepmc   +1 more source

The Cytoplasmic Domain of MHC Class I Molecules as a Molecular Switch: A Perspective from Short Linear Motifs and Intrinsically Disordered Regions. [PDF]

Biomolecules
Arosa FA, Cardoso EM.
europepmc   +1 more source