The Maximum Growth Temperature for Eukaryotes Is Thermodynamically Driven but Ecologically Contingent. [PDF]
Life (Basel)Bains W.
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Topological Entanglement in Intrinsically Disordered Proteins: Sequence, Structural, and Functional Determinants. [PDF]
J Phys Chem BYang W +4 more
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No Time to Fold: Intrinsically Disordered Microproteins in Action. [PDF]
BiochemistryChen T, Cao K, Martinez TF.
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Analysis and design of disordered polypeptides with optimized sequence patterning properties. [PDF]
PLoS Comput BiolSingh A +3 more
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Conformational dynamics and association of intrinsically disordered proteins (IDPs) using molecular dynamics simulationsNo 2nd Integrative Structural Biology ...
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Knowledge Distillation of a Protein Language Model Yields a Foundational Implicit Solvent Model. [PDF]
J Chem Theory ComputAiras J, Zhang B.
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Assessment of Missense Intolerant Regions (MIRs) in Intrinsically Disordered Proteins (IDPs)
Genes that are crucial for the function of an organism are depleted of disrupting variants in natural populations, whereas non-essential genes tolerate their accumulation. Next-generation sequencing (NGS) of the general population has enabled comprehensive coverage of the human genome, identifying single nucleotide variants (SNVs) at an impressive ...
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Shining light on the dark proteome with unstructural biology. [PDF]
Curr Res Struct BiolUversky VN.
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Comparing Enhanced Sampling Methods in Exploring the Conformational Space of β-Catenin<sub>17-48</sub>. [PDF]
J Phys Chem BGil Pineda LI +4 more
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Sequence-encoded conformational biases correlate with self-assembly modes of intrinsically disordered proteins. [PDF]
PNAS NexusKobayashi R +10 more
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