Results 61 to 70 of about 44,790 (294)

The effects of dietary supplementation with inulin and inulin‐propionate ester on hepatic steatosis in adults with non‐alcoholic fatty liver disease [PDF]

, 2018
The short chain fatty acid (SCFA) propionate, produced through fermentation of dietary fibre by the gut microbiota, has been shown to alter hepatic metabolic processes that reduce lipid storage.
Douglas J. Morrison, Preston, Tom, Frost, Gary, Catriona Tedford, Gary Frost, Preston, T, Akbar, Arne N., Chambers, ES, Morrison, D.J., Morrison, Douglas J., Tedford, Catriona, Thursz, Mark R., Bell, Jimmy, Riddell, Natalie, Morrison, DJ, Thursz, Mark, Rugyendo, A, Frost, G, Tedford, M.C., Thomas, E.L., Chambers, Edward, Louise Thomas, Chambers, Edward S., Akbar, AN, Thursz, MR, Bell, Jimmy D., Thursz, M.R., Manousou, P, Rohini Sharma, Manousou, Pinelopi, Riddell, N.E., Byrne, Claire, Byrne, C.S., Sharma, R, Akbar, Arne, Edward S. Chambers, Annette Rugyendo, Byrne, CS, Mark R. Thursz, Tedford, C, Byrne, Claire S., Morrison, Douglas, Natalie E. Riddell, Chambers, E.S., Thomas, Louise, Riddell, Natalie E., Frost, G., Thomas, E. Louise, Claire S. Byrne, Manousou, P., Tedford, M. Catriona, Rugyendo, A., Riddell, NE, Preston, T., Bell, JD, Arne N. Akbar, Sharma, R., Bell, J.D., Akbar, A.N., Rugyendo, Annette, Sharma, Rohini, Pinelopi Manousou, Thomas, L, Jimmy D. Bell, Tom Preston   +64 more
core   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Intestinal Sucrase as a Novel Target Contributing to the Regulation of Glycemia by Prebiotics.

PLoS ONE, 2016
Inulin-type fructans (ITF) are known for their capacity to modulate gut microbiota, energy metabolism and to improve glycemia in several animal models of obesity, and in humans.
Audrey M Neyrinck, Barbara Pachikian, Bernard Taminiau, Georges Daube, Raphaël Frédérick, Patrice D Cani, Laure B Bindels, Nathalie M Delzenne   +7 more
doaj   +1 more source

Mechanistic models for intermittent haemodialysis and haemodiafiltration clearance

British Journal of Clinical Pharmacology, EarlyView.
Haemodialysis has been used clinically for more than 70 years, but data regarding the clearance of medicines during dialysis are often based on studies with outdated, less efficient dialysers. Moreover, dialysis clearance is still frequently estimated using empirical approaches which lack mechanistic interpretability, are not readily generalizable ...
Laila Nassar, Nick Holford, Daniel Kurnik   +2 more
wiley   +1 more source

Dietary inulin supplementation improves meat quality and off-flavor of duck meat referring to regulated muscle fiber types and antioxidant capacity

Food Chemistry: X
This study aimed to evaluate the effects of dietary inulin (0–30 g/kg) on duck meat, muscle fiber types, meat quality, antioxidant ability, Low-field nuclear magnetic resonance, amino acid and off-flavor.
Hailei Sun, Jia Wang, Jina Han, Xiaolong Li, Juan Zhao, Yimin Zhang, Jingxin Sun   +6 more
doaj   +1 more source

Developing emulsion gels by incorporating Jerusalem artichoke inulin and investigating their lipid oxidative stability

Food Production, Processing and Nutrition, 2020
This study investigated physical, chemical and lipid oxidative properties of emulsion gels (W/O) incorporating Jerusalem artichoke (JA) inulin. Primary purified inulin extract (PPIE, 1%) improved the homogeneity of emulsion gel (with no syneresis) and ...
Feijie Li, Aynur Gunenc, Farah Hosseinian   +2 more
doaj   +1 more source

Advances in Sustainable Production of Bio‐Derived 5‐Alkoxymethylfurfural and Levulinate Esters: A Comprehensive Review

Carbon Energy, EarlyView.
The present review discusses the advancement in the catalytic synthesis of 5‐alkoxymethylfurfural (AMF) and levulinate esters (LEs) from the aspects of catalytic systems, reaction mechanisms, product isolation, and techno‐economic analysis, supplying valuable insights toward future sustainable and efficient manufacture of AMF and LEs. ABSTRACT The huge
Jun Zhang, Chunxiang Yang, Yuhe Liao, Jiawei Wang, Chengyu Li, Rui Shan, Haoran Yuan   +6 more
wiley   +1 more source

Maternal Inulin Supplementation Alters Hepatic DNA Methylation Profile and Improves Glucose Metabolism in Offspring Mice

Frontiers in Physiology, 2020
ScopeAs a prebiotic, inulin may have a protective effect on glucose metabolism. However, the mechanism of inulin treatment on glucose intolerance in offspring exposed to a maternal high-fat (HF) diet is still not clear.
Qian Zhang, Xinhua Xiao, Jia Zheng, Ming Li, Miao Yu, Fan Ping, Tong Wang, Xiaojing Wang   +7 more
doaj   +1 more source

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

Chemistry – A European Journal, EarlyView.
Unlocking the chemistry of caramel by simulations and experimental validation. αFFase1${\alpha }\rm{FFase1}$ converts inulobiose into difructose dianhydride I, one component of caramel, through two steps: a rate‐limiting glycosylation (with a rare sugar ring flip) followed by a cyclization step, guided by residues E85, K147, and N226.
Santiago Alonso‐Gil, Bruno Di Geronimo, Toma Kashima, Akihiro Ishiwata, Katsunori Tanaka, Kiyotaka Fujita, Shinya Fushinobu, Pedro A. Sánchez‐Murcia   +7 more
wiley   +1 more source

Inulin - a versatile polysaccharide with multiple pharmaceutical and food chemical uses [PDF]

, 2016
alpha-D-glucopyranosyl-[beta-D-fructofuranosyl](n-1)-D-fructofuranoside, commonly referred to as inulin, is a natural plant-derived polysaccharide with a diverse range of food and pharmaceutical applications.
Nikolai Petrovsky, Milena Ginic-Markovic, Peter Cooper, Thomas Barclay   +3 more
core