Results 41 to 50 of about 5,284,490 (388)

Calcium-permeable ion channels in control of autophagy and cancer

Frontiers in Physiology, 2013
Autophagy, or cellular self-eating, is a tightly regulated cellular pathway the main purpose of which is lysosomal degradation and subsequent recycling of cytoplasmic material to maintain normal cellular homeostasis.
Artem eKondratskyi, Maya eYassine, Kateryna eKondratska, Roman eSkryma, Christian eSlomianny, Natalia ePrevarskaya   +5 more
doaj   +1 more source

Multiple Thresholds in a Model System of Noisy Ion Channels [PDF]

, 2006
Voltage-activated ion channels vary randomly between open and closed states, influenced by the membrane potential and other factors. Signal transduction is enhanced by noise in a simple ion channel model.
D. Johnston, F. Rieke, F. Theunissen, J.-H. Lee, Manfred L. Ristig, Michael J. Barber   +5 more
core   +1 more source

P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]

, 2008
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
Brian F. King, Bucheimer RE, Dai LJ, Dubyak GR, Egan TM, Inscho EW, King BF, Lazarowski ER, Lazarowski ER, Lehrmann H, Leipziger J, Li L, McCoy DE, North RA, Pelegrin P, Piper AS, Ralevic V, Schwiebert EM, Scott S.P. Wildman, Shirley DG, Taylor AL, Unwin RJ, Vekaria R, Wildman SS, Wildman SS, Wildman SS, Wildman SS, Wildman SS, Wolff SC, Zhang Y   +29 more
core   +1 more source

Synthetic Ion Channels

Langmuir, 2013
The objective of this historical review is to recall the development of the field of synthetic ion channels over the past three decades. The most inspiring and influential breakthroughs with regard to structure and function are brought together to give the general reader an easily accessible understanding of the field.
Sakai Naomi, Matile Stefan
openaire   +4 more sources

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. [PDF]

, 2014
Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
Arce, Fernando Teran, Cohen, Daniel A, Lal, Ratnesh, Patel, Nirav R, Quist, Arjan P, Ramachandran, Srinivasan   +5 more
core   +2 more sources

Ion channel activity drives ion channel expression [PDF]

The Journal of Physiology, 1998
During embryonic development, excitable cells acquire a repertoire of ion channels that finely tune their electrical properties. Although the mechanisms by which an excitable cell selects its complement of ion channels are poorly defined, cell-autonomous as well as non-autonomous programmes of differentiation have been implicated.
openaire   +2 more sources

Roles of ion channels in immune cells [PDF]

, 2016
The Editorial on the Research Topic - Roles of Ion Channels in Immune ...
Amanda eMacKenzie, Leanne eStokes, Leanne eStokes, Ronald eSluyter, Ronald eSluyter, Ronald eSluyter   +5 more
core   +3 more sources

Cardiac Ion Channels [PDF]

Circulation: Arrhythmia and Electrophysiology, 2009
The analysis of the molecular basis of the inherited cardiac arrhythmias has been the driving force behind the identification of the ion channels that generate the action potential. The genes encoding all the major ion channels have cloned and sequenced. The studies have revealed greater complexity than heretofore imagined.
openaire   +2 more sources

Suppression of nano-channel ion conductance by electro-osmotic flow in nano-channels with weakly overlapping electrical double layers [PDF]

, 2016
This theoretical study investigates the nonlinear ionic current-voltage characteristics of nano-channels that have weakly overlapping electrical double layers.
Dutton, Robert, Guo, Lingzi, Liu, Yang, Ran, Qiushi, Zhu, Xin   +4 more
core   +3 more sources

PTPRM Is Critical for Synapse Formation Regulated by Zinc Ion

Frontiers in Molecular Neuroscience, 2022
In the nervous system, the trace metal ion zinc is required for normal mammalian brain development and physiology. Zinc homeostasis is essential for the control of physiological and pathophysiological brain functions.
Xiaoqiang Mo, Xiaoqiang Mo, Mengxue Liu, Jihong Gong, Ying Mei, Huidan Chen, Huajun Mo, Xiaofei Yang, Jun Li   +8 more
doaj   +1 more source