Results 61 to 70 of about 58,639 (306)

Efeito da monensina e extrato de própolis sobre a produção de amônia e degradabilidade in vitro da proteína bruta de diferentes fontes de nitrogênio Effect of monensin and propolis extract on ammonia production and in vitro degradability of crude protein of different nitrogen sources

Revista Brasileira de Zootecnia, 2004
Este experimento foi conduzido com o objetivo de avaliar a fermentação da proteína de três fontes de nitrogênio (tripticase, farelo de soja e farinha de peixe), com ou sem monensina ou extrato de própolis.
Juliana Silva Oliveira, Rogério de Paula Lana, Arnaldo Chaer Borges, Augusto César de Queiroz, Ivan Carlos C. Almeida   +4 more
doaj   +1 more source

Epoxide-Opening Cascades in the Synthesis of Polycyclic Polyether Natural Products [PDF]

, 2009
The structural features of polycyclic polyether natural products can, in some cases, be traced to their biosynthetic origin. However in case that are less well understood, only biosynthetic pathways that feature dramatic, yet speculative, epoxide-opening
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core   +1 more source

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

PLoS Pathogens, 2010
Increasing the intracellular Zn2+ concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus.
A. J. T. te Velthuis, S. V. D. van den Worm, A. Sims, R. Baric, E. Snijder, M. V. van Hemert   +5 more
semanticscholar   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

Liquid-Liquid Extraction Study of Sodium and Potassium Ions by a Series of Non Cyclic Ionophores Composed of Furan Units [PDF]

Journal of Sciences, Islamic Republic of Iran, 2012
A new series of noncyclic ionophores containing two to four furan units (Ia to IIIb) i.e. 1,1-difurylethane (Ia), 2,5-bis(methylfurfuryl)furan (IIa) and 1,1’ ethyledenebis[5-(methylfurfuryl)furan] (IIIa), 2,2-difurylpropane (Ib), 2,5-bis ...
L. Lokwani
doaj  

Photosynthesis dependent acidification of perialgal vacuoles in theParamedum bursaria/Chlorella symbiosis. Visualization by monensin [PDF]

, 1992
After treatment with the carboxylic ionophore monensin theChlorella containing perialgal vacuoles of the greenParamecium bursaria swell. TheParamecium cells remain motile at this concentration for at least one day.
A Fischer, AM Tartakoff, AM Tartakoff, B Matzke, BC Pressmann, DC Smith, E Cernichiari, E Kessler, H Kleinig, HH Mollenhauer, J Larsen, J Willenbrink, L Muscatine, MJ Geisow, N Stelly, R Sandeaux, TC Hohman, W Reisser, W Reisser, W Reisser, W Reisser, WF Boss   +21 more
core   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Carcass quality of feedlot finished steers fed yeast, monensin, and the association of both additives Qualidade de carcaça de novilhos terminados com dietas contendo levedura, monensina e associação de ambos aditivos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2009
To evaluate the effects of the supplementation of feed additives on carcass quality in beef cattle, 72 Nellore steers (339.5kg, 20-month old) were feedlot finished and fed for 91 days one of the following diets: 1) control with no additives; or added of ...
R.C. Gomes, P.R. Leme, S.L. Silva, M.T. Antunes, C.F. Guedes   +4 more
doaj   +1 more source