Results 11 to 20 of about 59,051 (256)

Electrophysiology of ionotropic GABA receptors [PDF]

open access: yesCellular and Molecular Life Sciences, 2021
AbstractGABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and diverse roles GABAA receptors play in the regulation of neuronal communication and the functioning of the brain.
Erwan Sallard   +2 more
openaire   +4 more sources

Non-ionotropic signaling by the NMDA receptor: controversy and opportunity [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Provocative emerging evidence suggests that the N-methyl-D-aspartate (NMDA) receptor can signal in the absence of ion flux through the receptor. This non-ionotropic signaling is thought to be due to agonist-induced conformational changes in the receptor,
John A. Gray   +2 more
doaj   +1 more source

Presynaptic ionotropic receptors

open access: yesCurrent Opinion in Neurobiology, 1996
Recent studies have provided new insights into the role of presynaptic ligand-gated ion channels in modifying synaptic transmission. Along with a growing list of different types of presynaptic ionotropic receptors and the cell types that express them, there have been advances in characterizing the molecular components of the receptors as well as the ...
D S, McGehee, L W, Role
openaire   +2 more sources

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics

open access: yesFrontiers in Cellular Neuroscience, 2014
The central nucleus of amygdala (CeA) has a role for mediating fear and anxiety responses. It is also involved in emotional imbalance caused by alcohol abuse and dependence and in regulating relapse to alcohol abuse.
Zhe eJin   +6 more
doaj   +1 more source

Positive allosteric modulators of the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor [PDF]

open access: yes, 2010
L-glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) and plays a fundamental role in the control of motor function, cognition and mood.
Grove, Simon J .A.   +4 more
core   +1 more source

Glutamate, GABA and acetylcholine signaling components in the lamina of the Drosophila visual system. [PDF]

open access: yesPLoS ONE, 2008
Synaptic connections of neurons in the Drosophila lamina, the most peripheral synaptic region of the visual system, have been comprehensively described.
Agata Kolodziejczyk   +3 more
doaj   +1 more source

More than meets the IR: the expanding roles of variant Ionotropic Glutamate Receptors in sensing odor, taste, temperature and moisture [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
The ionotropic receptors (IRs) are a branch of the ionotropic glutamate receptor family and serve as important mediators of sensory transduction in invertebrates.
Lena van Giesen, Paul A. Garrity
doaj   +1 more source

Predominantly linear summation of metabotropic postsynaptic potentials follows coactivation of neurogliaform interneurons

open access: yeseLife, 2021
Summation of ionotropic receptor-mediated responses is critical in neuronal computation by shaping input-output characteristics of neurons. However, arithmetics of summation for metabotropic signals are not known. We characterized the combined ionotropic
Attila Ozsvár   +5 more
doaj   +1 more source

Rapid evolution of chemosensory receptor genes in a pair of sibling species of orchid bees (Apidae: Euglossini). [PDF]

open access: yes, 2015
BackgroundInsects rely more on chemical signals (semiochemicals) than on any other sensory modality to find, identify, and choose mates. In most insects, pheromone production is typically regulated through biosynthetic pathways, whereas pheromone sensory
Brand, Philipp   +5 more
core   +3 more sources

Comparison of transcriptomes from two chemosensory organs in four decapod crustaceans reveals hundreds of candidate chemoreceptor proteins.

open access: yesPLoS ONE, 2020
Crustaceans express genes for at least three classes of putative chemosensory proteins. These are: Ionotropic Receptors (IRs), derived from the heterotetrameric ionotropic glutamate receptors (iGluRs); Transient Receptor Potential (TRP) channels, a ...
Mihika T Kozma   +7 more
doaj   +1 more source

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