Results 41 to 50 of about 59,051 (256)

The prion protein regulates glutamate-mediated Ca2+ entry and mitochondrial Ca2+ accumulation in neurons [PDF]

open access: yes, 2017
The cellular prion protein (PrPC) whose conformational misfolding leads to the production of deadly prions, has a still-unclarified cellular function despite decades of intensive research.
Bertoli, Alessandro   +8 more
core   +1 more source

Nicotinic α7 acetylcholine receptor-mediated currents are not modulated by the tryptophan metabolite kynurenic acid in adult hippocampal interneurons [PDF]

open access: yes, 2011
The  tryptophan  metabolite,  kynurenic  acid (KYNA),  is  classically  known  to  be  an antagonist  of ionotropic glutamate receptors.
Andrew L. Varnell   +3 more
core   +3 more sources

GABA_{B} Receptors Regulate Chick Retinal Calcium Waves [PDF]

open access: yes, 2001
Correlated spiking activity and associated Ca²⁺ waves in the developing retina are important in determining the connectivity of the visual system. Here, we show that GABA, via GABA_{B} receptors, regulates the temporal characteristics of Ca²⁺ waves ...
Catsicas, M, Mobbs, P
core  

Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]

open access: yes, 2013
NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H   +4 more
core   +2 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

Interferon-γ acutely augments inhibition of neocortical layer 5 pyramidal neurons [PDF]

open access: yes, 2020
BACKGROUND: Interferon-γ (IFN-γ, a type II IFN) is present in the central nervous system (CNS) under various conditions. Evidence is emerging that, in addition to its immunological role, IFN-γ modulates neuronal morphology, function, and development in ...
Bräuer, Anja U.   +7 more
core   +1 more source

Magnetic Textiles: A Review of Materials, Fabrication, Properties, and Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Magnetic textiles (M‐textiles) are emerging as a programmable materials platform that merges magnetic matter with hierarchical textile structures. This article consolidates magnetic material classes, textile architectures, and fabrication and magnetization strategies, revealing structure–property–function relationships that govern magneto‐mechanical ...
Li Ke   +3 more
wiley   +1 more source

Group 1 metabotropic glutamate receptor function and its regulation of learning and memory in the aging brain

open access: yesFrontiers in Pharmacology, 2012
Normal aging is generally characterized by a slow decline of cognitive abilities albeit with marked individual differences. Several animal models have been studied to explore the molecular and cellular mechanisms underlying this phenomenon.
Caroline eMénard, Rémi eQuirion
doaj   +1 more source

Ionotropic receptors mediate nitrogenous waste avoidance in Drosophila melanogaster

open access: yesCommunications Biology, 2021
Dhakal et al. use chemoreceptor screening on three ionotropic receptors in Drosophila, IR25a, IR76b, IR51b to evaluate their impact on avoidance behaviors against nitrogenous waste products.
Subash Dhakal   +3 more
doaj   +1 more source

Neuroanatomical changes of ionotropic glutamatergic and GABAergic receptor densities in male mice modeling idiopathic and syndromic autism spectrum disorder

open access: yesFrontiers in Psychiatry, 2023
Autism spectrum disorder (ASD) comprises a wide range of neurodevelopment conditions primarily characterized by impaired social interaction and repetitive behavior, accompanied by a variable degree of neuropsychiatric characteristics.
Leonardo Nardi   +9 more
doaj   +1 more source

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