Results 21 to 30 of about 33,342 (190)

Electrophysiology of ionotropic GABA receptors [PDF]

Cellular and Molecular Life Sciences, 2021
AbstractGABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and diverse roles GABAA receptors play in the regulation of neuronal communication and the functioning of the brain.
Erwan Sallard, Diane Letourneur, Pascal Legendre   +2 more
openaire   +4 more sources

OPINION: History and Perspectives of ASICs

BBA Advances, 2023
The author recalls several particularly memorable events during his scientific career that led to the discovery of acid-sensing ion channels and ionotropic purinergic receptors.
Oleg Krishtal
doaj   +1 more source

Insect odorant response sensitivity is tuned by metabotropically autoregulated olfactory receptors. [PDF]

PLoS ONE, 2013
Insects possess one of the most exquisitely sensitive olfactory systems in the animal kingdom, consisting of three different types of chemosensory receptors: ionotropic glutamate-like receptors (IRs), gustatory receptors (GRs) and odorant receptors (ORs).
Merid N Getahun, Shannon B Olsson, Sofia Lavista-Llanos, Bill S Hansson, Dieter Wicher   +4 more
doaj   +1 more source

Ionotropic and metabotropic responses by alpha 7 nicotinic acetylcholine receptors

Pharmacological Research, 2023
Nicotinic acetylcholine receptors (nAChRs) belong to a superfamily of cys-loop receptors characterized by the assembly of five subunits into a multi-protein channel complex.
Patricia Sinclair, Nadine Kabbani
doaj   +1 more source

Synaptic Efficacy as a Function of Ionotropic Receptor Distribution: A Computational Study. [PDF]

PLoS ONE, 2015
Glutamatergic synapses are the most prevalent functional elements of information processing in the brain. Changes in pre-synaptic activity and in the function of various post-synaptic elements contribute to generate a large variety of synaptic responses.
Sushmita L Allam, Jean-Marie C Bouteiller, Eric Y Hu, Nicolas Ambert, Renaud Greget, Serge Bischoff, Michel Baudry, Theodore W Berger   +7 more
doaj   +1 more source

A C. elegans genome-wide RNAi screen for altered levamisole sensitivity identifies genes required for muscle function

G3: Genes, Genomes, Genetics, 2021
At the neuromuscular junction (NMJ), postsynaptic ionotropic acetylcholine receptors (AChRs) transduce a chemical signal released from a cholinergic motor neuron into an electrical signal to induce muscle contraction.
Timothy Chaya, Shrey Patel, Erin M Smith, Andy Lam, Elaine N Miller, Michael Clupper, Kirsten Kervin, Jessica E Tanis   +7 more
doaj   +1 more source

Predominantly linear summation of metabotropic postsynaptic potentials follows coactivation of neurogliaform interneurons

eLife, 2021
Summation of ionotropic receptor-mediated responses is critical in neuronal computation by shaping input-output characteristics of neurons. However, arithmetics of summation for metabotropic signals are not known. We characterized the combined ionotropic
Attila Ozsvár, Gergely Komlósi, Gáspár Oláh, Judith Baka, Gábor Molnár, Gábor Tamás   +5 more
doaj   +1 more source

An Insight into Animal Glutamate Receptors Homolog of Arabidopsis thaliana and Their Potential Applications—A Review

Plants, 2022
Most excitatory impulses received by neurons are mediated by ionotropic glutamate receptors (iGluRs). These receptors are located at the apex and play an important role in memory, neuronal development, and synaptic plasticity.
Ruphi Naz, Andleeb Khan, Badrah S. Alghamdi, Ghulam Md Ashraf, Maimonah Alghanmi, Altaf Ahmad, Sheikh Shanawaz Bashir, Qazi Mohd Rizwanul Haq   +7 more
doaj   +1 more source

Pharmacological analysis of ionotropic glutamate receptor function in neuronal circuits of the zebrafish olfactory bulb. [PDF]

PLoS ONE, 2008
Although synaptic functions of ionotropic glutamate receptors in the olfactory bulb have been studied in vitro, their roles in pattern processing in the intact system remain controversial.
Rico Tabor, Rainer W Friedrich
doaj   +1 more source

Presynaptic ionotropic receptors

Current Opinion in Neurobiology, 1996
Recent studies have provided new insights into the role of presynaptic ligand-gated ion channels in modifying synaptic transmission. Along with a growing list of different types of presynaptic ionotropic receptors and the cell types that express them, there have been advances in characterizing the molecular components of the receptors as well as the ...
D S, McGehee, L W, Role
openaire   +2 more sources