Results 101 to 110 of about 9,735 (211)

Phytic acid (IP6), novel broad spectrum anti-neoplastic agent: a systematic review

open access: yesComplementary Therapies in Medicine, 2002
Phytic acid or IP6 has been extensively studied in animals and is being promoted as an anti-cancer agent in health food stores. It is naturally found in legumes, wheat bran, and soy foods. It is believed to be the active ingredient that gives these substances their cancer fighting abilities.
C H, Fox, M, Eberl
openaire   +2 more sources

Biological and mechanical performance of calcium phosphate cements modified with phytic acid

open access: yesJournal of Materials Science: Materials in Medicine
Calcium phosphate cements, primarily brushite cements, require the addition of setting retarders to ensure adequate processing time and processability. So far, citric acid has been the primary setting retarder used in this context.
Valentin C. Steinacker   +10 more
doaj   +1 more source

Structural and functional analysis of mRNA export regulation by the nuclear pore complex [PDF]

open access: yes, 2018
The nuclear pore complex (NPC) controls the passage of macromolecules between the nucleus and cytoplasm, but how the NPC directly participates in macromolecular transport remains poorly understood.
Cai, Sarah W.   +5 more
core   +1 more source

Differential Influence of Inositol Hexaphosphate on the Expression of Genes Encoding TGF-β Isoforms and Their Receptors in Intestinal Epithelial Cells Stimulated with Proinflammatory Agents

open access: yesMediators of Inflammation, 2013
Transforming growth factor β (TGF-β) is a multifunctional cytokine recognized as an important regulator of inflammatory responses. The effect of inositol hexaphosphate (IP6), a naturally occurring phytochemical, on the mRNA expression of TGF-β1, TGF-β2 ...
Małgorzata Kapral   +3 more
doaj   +1 more source

HIV needs the small molecule IP6 to build its capsid

open access: yes, 2022
The retrovirus Human Immunodeficiency Virus Type-1 (HIV-1) infects cells of the immune system causing their depletion and resulting in the Acquired Immunodeficiency Syndrome (AIDS). The viral capsid protein (CA) is essential for replication. Upon budding of a new HIV particle, CA is part of the Gag polyprotein which assembles into an immature virus ...
openaire   +1 more source

Analysis of Dictyostelium discoideum Inositol Pyrophosphate Metabolism by Gel Electrophoresis. [PDF]

open access: yes, 2014
The social amoeba Dictyostelium discoideum was instrumental in the discovery and early characterization of inositol pyrophosphates, a class of molecules possessing highly-energetic pyrophosphate bonds.
Chubb, JR   +5 more
core  

Inositol hexakisphosphate (IP6) enhances the electrical excitability of Characean Nitellopsis obtusa

open access: yesPlant Stress
Despite the importance of action potentials (APs) in plant stress physiology, the molecular identity of Ca2+ channels that initiate APs by passing Ca2+ into the cytoplasm is still unknown in Characean macroalgae. While the Thiel-Beilby mathematical model
Vilmantas Pupkis   +3 more
doaj   +1 more source

Preliminary investigation of myo-inositol phosphates produced by ASUIA279 phytase on MCF-7 cancer cells. [PDF]

open access: yes, 2011
Phytate or myo-inositol hexakisphosphates (IP6) is widely distributed in plants like rice brans. The production of myo-inositol phosphate intermediates has received much attention due to the remarkable potential health benefits offered by the compounds ...
Abd. El Aziem, Farouk   +7 more
core  

Molecular mechanisms for the antitumor activity of inositol hexakisphosphate (IP6).

open access: yesCancer genomics & proteomics, 2007
Inositol hexakisphosphate (IP6), a naturally occurring polyphosphorylated carbohydrate, has been reported to have significant in vivo and in vitro anticancer activity against numerous tumors. However, the molecular mechanism of the anticancer effect of IP6 has not been fully elucidated.Using K-562 human leukemia cells we analysed the induction of the ...
Anikó, Bozsik   +2 more
openaire   +1 more source

Oracle of phytic acid in dental panacea – Insight into properties, therapeutic effect, regeneration, materials interaction and oral physiology

open access: yesSaudi Dental Journal
Phytic acid (inositol hexaphosphate/IP6) is a versatile chemical that is abundant in nature and is required for a variety of biological processes. It is harnessed in a wide range of fields, including drug discovery, daily supplies, chemical industries ...
Ummey Salma   +7 more
doaj   +1 more source

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