Results 81 to 90 of about 2,694 (167)

Molecular mechanisms for the antitumor activity of inositol hexakisphosphate (IP6).

Cancer genomics & proteomics, 2007
Inositol hexakisphosphate (IP6), a naturally occurring polyphosphorylated carbohydrate, has been reported to have significant in vivo and in vitro anticancer activity against numerous tumors. However, the molecular mechanism of the anticancer effect of IP6 has not been fully elucidated.Using K-562 human leukemia cells we analysed the induction of the ...
Anikó, Bozsik, Szabolcs, Kökény, Edith, Olah   +2 more
openaire   +1 more source

Cancer Preventive and Therapeutic Properties of IP6: Efficacy and Mechanisms

Periodicum biologorum, 2010
Recently, IP6 has received much attention for its role in cancer prevention, and control of experimental tumor growth and progression. A striking, consistent and reproducible anticancer action of IP6 has been demonstrated in various experimental models.
VUČENIK, IVANA, STAINS, JOSEPH
openaire   +2 more sources

Multifunctional ionic thermoelectric elastomer enhanced by Le Chatlier principle in synergistic supramolecular hydrogen bonding system. [PDF]

Sci Adv
Jin Y, Peng S, Yan C, Chen X, Zhang X, Tian M, Cao Z, Wang T, Chen B.   +8 more
europepmc   +1 more source

Preparation of amorphous calcium phosphate nanoparticles using small organic molecules for biomimetic mineralization of dentin. [PDF]

RSC Adv
Liu Z, Li D, Shi X, Xiao D, Shi F, Luo X, Feng G, Xie Y, Zhang C.   +8 more
europepmc   +1 more source

Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly. [PDF]

Proc Natl Acad Sci U S A
Gupta M, Waltmann C, Renner N, Wang Y, James LC, Jacques DA, Böcking T, Voth GA.   +7 more
europepmc   +1 more source

Targeting IP₆ signaling to destabilize homologous recombination proteins to overcome PARP inhibitor resistance. [PDF]

Nat Commun
Lee SG, Seo Y, Jeong S, Chung Y, Kong S, Kim M, Rhlee JH, Um S, Mathew BP, Maiti S, Kuram MR, Abozeid MA, Park A, Yoo JN, Khim KW, Son K, Amarsanaa E, Kim K, Hong S, Choi J, Park IB, Lee EA, Jeon JH, Park JH, Han JS, Park CY, Kim S, Choi JH, Hong SY, Seo MD, Lee H, Lee JY, Myung K.   +32 more
europepmc   +1 more source

OsIPK2 Regulates Seed Vigor by Integrating IP₆ Biosynthesis, Auxin Signaling, and H3K27me3 Deposition in Japonica Rice. [PDF]

Biology (Basel)
Chen Y, Li Y, Sang S.
europepmc   +1 more source

Transient Occupancy and Pore Dynamics: IP6 Behavior in HIV-1 <i>T</i> = 4 Capsids. [PDF]

J Phys Chem B
Macke AC, Xu C, Sudhakar S, Perilla JR.
europepmc   +1 more source

A bacterial YopJ-family acetyltransferase suppresses host immune response by Nε-acetylation of JAK1. [PDF]

Nat Commun
Chen TT, Zheng SR, Yang B, Lu Q, Liu X, Zhong W, Jiang Z, Li F, Hu G, Feng Y, Hu C, Su J, Ouyang S.   +12 more
europepmc   +1 more source

Versatile roles of inositol hexakisphosphate in the ubiquitin-proteasome system. [PDF]

Essays Biochem
Rusnac DV, Zheng N, Xie X.
europepmc   +1 more source