Results 111 to 120 of about 573 (120)
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Blood
Abstract Background: Cancer-associated thrombosis (CAT) is driven by multiple procoagulant mechanisms. Immune checkpoint inhibitors (ICI), while enhancing antitumor immunity, are linked to an increased risk of thrombosis (ICI-associated thrombosis, IAT).
Young Jun Shim +2 more
openaire +1 more source
Abstract Background: Cancer-associated thrombosis (CAT) is driven by multiple procoagulant mechanisms. Immune checkpoint inhibitors (ICI), while enhancing antitumor immunity, are linked to an increased risk of thrombosis (ICI-associated thrombosis, IAT).
Young Jun Shim +2 more
openaire +1 more source
The activation of miR-125a-5p/IP6K1 axis in breast cancer cells upon treatment with myo-Inositol.
2019Several studies have been performed with the aim of identifying drugs able in inhibiting Epithelial-Mesenchymal Transition (EMT), chiefly by blocking PI3K/Akt pathway. We have already demonstrated that treatment with myo-Inositol at the pharmacological dose can block EMT in breast cancer cells by downregulating PI3K/Akt and inducing changes in ...
Mirko Minini +6 more
openaire +1 more source
Myo-Inositol treatment inhibits motility in triple negative breast cancer via miR-125a-5p/IP6K1 axis
2019Background: Several researches have been performed with the aim of identifying drugs able in blocking PI3K/Akt pathway. We have already demonstrated that myo-Inositol (myo-Ins) treatment can block EMT in breast cancer cells by downregulating PI3K/Akt and inducing changes in cytoskeletal architecture.
Minini Mirko +8 more
openaire +1 more source
Regulation of IP6K1 gene expression: role of the proximal promoter GC-rich Sp1 binding region
2012DE LUCA, Antonella +5 more
openaire +1 more source