Results 101 to 110 of about 573 (120)

Mammalian mitochondrial inorganic polyphosphate (polyP) and cell signaling: Crosstalk between polyP and the activity of AMPK. [PDF]

open access: yesMol Metab
Da Costa RT   +10 more
europepmc   +1 more source

Nongenetic and Genetic Factors Associated with White Matter Brain Aging: Exposome-Wide and Genome-Wide Association Study. [PDF]

open access: yesGenes (Basel)
Feng L   +11 more
europepmc   +1 more source

Computer-Aided Drug Design and Drug Discovery. [PDF]

open access: yesPharmaceuticals (Basel)
Mihai DP, Nitulescu GM.
europepmc   +1 more source

Meta-analysis of uveal melanoma genome-wide association studies identifies novel risk loci and population effect size heterogeneity. [PDF]

open access: yesHGG Adv
Mies G   +13 more
europepmc   +1 more source

Synthesis of InsP 7 by the Inositol Hexakisphosphate Kinase 1 (IP6K1)

Methods in Molecular Biology, 2010
Soluble inositol polyphosphates represent a variegate class of signalling molecules essential for the function of disparate cellular processes. Recently, the phytic acid derivate inositol pyrophosphate, InsP(7) (PP-IP(5) or IP(7)) has been shown to pyro-phosphorylate proteins in a kinase independent way. To begin to understand the functional importance
Cristina Azevedo   +2 more
exaly   +3 more sources

miR-125a-5p impairs the metastatic potential in breast cancer via IP6K1 targeting

Cancer Letters, 2021
The deregulation of PI3K/Akt signaling is among the most causes in inducing the acquisition of a metastatic phenotype in breast cancer cells, leading to Epithelial-Mesenchymal Transition (EMT). Inhibition of the PI3K/Akt pathway is known to be beneficial in the clinical setting.
Minini M.   +11 more
openaire   +2 more sources

IP6K1 Sees the Light

Science Signaling, 2014
UV light prevents the inhibition of the E3 ubiquitin ligase complex CRL4 by IP6K1.
openaire   +1 more source

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