Results 81 to 90 of about 737 (136)

Inositol hexakisphosphate kinase 1 is essential for cell junction integrity in the mouse seminiferous epithelium

Inositol hexakisphosphate kinases (IP6Ks) are enzymes that catalyse the synthesis of the inositol pyrophosphate 5-IP7 which is involved in the regulation of many physiological processes in mammals.
Aushaq Bashir Malla, Sen, Jayraj, Bhat, Sameer Ahmed, Vineesha Oddi, Sameer Ahmed Bhat, Rashna Bhandari, Malla, Aushaq Bashir, Oddi, Vineesha, Jayraj Sen, Bhandari, Rashna   +9 more
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이노시톨 다인산 대사의 CD4 도움 T 세포 기능 및 분화 조절 역할 규명에 대한 연구

, 2020
학위논문(박사) - 한국과학기술원 : 의과학학제전공, 2020.2,[vii, 112 p. :]Inositol polyphosphate multikinase (IPMK) physiologically creates IP4 and IP5. IPMK is also known as an important phosphatidylinositol 3 kinase (PI3K) that forms PIP3 which activates Akt and influences ...
육채민
core  

Synthesis of InsP₇s and InsP₈ by IP6Ks and PPIP5Ks.

, 2016
The Fig describes the synthesis of 1-InsP7, 5-InsP7 and 1,5-InsP8 in both yeasts and mammalian cells. IP6K1/2/3 = isoforms 1, 2 and 3 of inositol hexakisphosphate kinase (Kcs1 is the single yeast isoform); PPIP5K1/2 = isoforms 1 and 2 of ...
Chunfang Gu (245490), Adolfo Saiardi (263859), Stephen B. Shears (528105), Henning J. Jessen (1500052), Miranda S. C. Wilson (3280074)   +4 more
core   +1 more source

IP6K1 Gene [PDF]

, 2020
openaire   +1 more source

IP6K1 wt Allele [PDF]

, 2020
openaire   +1 more source

Inositol pyrophosphates and Akt/PKB: Is the pancreatic beta-cell the exception to the rule?

, 2019
The inositol pyrophosphate, diphosphoinositol pentakisphosphate (IP7), is thought to negatively regulate the critical insulin signaling protein Akt/PKB.
Barker, Christopher J., Ryu, Sung Ho, Kim, J, Barker, CJ, Dare, E,, Berggren, P-O, Rajasekaran, SS, Kim, Jaeyoon, Berggren, Per-Olof, Ryu, SH, Dare, Elisabetta, Rajasekaran, Subu Surendran   +11 more
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Fragment-Based Screening Identifies New Quinazolinone-Based Inositol Hexakisphosphate Kinase (IP6K) Inhibitors. [PDF]

ACS Med Chem Lett, 2023
Heitmann T, Liao G, de León P, Ernst G, Buchler I, Wei H, Shlevkov E, Brown D, Fitzek M, Collier M, Smith DM, Barrow JC.   +11 more
europepmc   +1 more source

Inositol pyrophosphates inhibit synaptotagmin-dependent exocytosis

, 2018
Inositol pyrophosphates such as 5-diphosphoinositol pentakisphosphate (5-IP7) are highly energetic inositol metabolites containing phosphoanhydride bonds. Although inositol pyrophosphates are known to regulate various biological events, including growth,
Tae-Young Yoon, Kim, S, Kyung, JW, Yang, Y, Jho, YS, Kweon, DH, Kong, B, Kim, SH, Park, SJ, Jessen, HJ, Pavlovic, I, Lee, JY, Shin, YK, Lee, S, Tae-Sun Lee   +14 more
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The inositol pyrophosphate 5-InsP₇ regulates mitochondrial polyphosphate synthesis and bioenergetic function. [PDF]

J Biol Chem
Ladke JS, Khan A, Singh A, Jessen HJ, Kolthur-Seetharam U, Jaiswal M, Bhandari R.   +6 more
europepmc   +1 more source

The DsbA-L paradox in protective and pathogenic stress adaptation. [PDF]

iScience
Deng Y, Yan L, Liu X, Xiao T, Meng W.
europepmc   +1 more source