Results 91 to 100 of about 1,062 (145)
Inositol phosphate pathway evolution and synthesis in Dictyostelium discoideum [PDF]
Inositol phosphates (InsPs) are polar water-soluble derivatives of the six- carbon cyclitol inositol. They are synthesized, through phosphorylation reactions, by kinases of four distinct families: IPK, IP5-2K, ITPK1 and PPIP5K, which are thought to be ...
Portela Torres, Paloma
core
Inositol Pyrophosphates: Energetic, Omnipresent and Versatile Signalling Molecules [PDF]
Inositol pyrophosphates (PP-IPs) are a class of energy-rich signalling molecules found in all eukaryotic cells. These are derivatives of inositol that contain one or more diphosphate (or pyrophosphate) groups in addition to monophosphates.
A Burton +130 more
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Novel Regulatory Mechanisms Of Inositol Biosynthesis In Saccharomyces Cerevisiae And Mammalian Cells, And Implications For The Mechanism Underlying Vpa-Induced Glucose 6-Phosphate Depletion [PDF]
Myo-inositol is the precursor of all inositol containing molecules, including inositol phosphates, phosphoinositides and glycosylphosphatidylinositols, which are signaling molecules involved in many critical cellular functions.
Yu, Wenxi
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ALOE VERA: AN ASSURED WEIGHT LOSS DIET – AN APPROACH TOWARD IMPROVING THE JUICE PALATABILITY AND IN SILICO ANALYSIS [PDF]
Objective: Obesity is an epidemic disease act as causative for global death. The principal aim of this study is to create an obesity treatment beverage that is palatable and readily acceptable to the public.
DISALVA X, MAHENDRAN RADHA, SHARANYA M
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Background Inositol hexakisphosphate Kinase 1 (IP6K1) has been identified as a key signalling enzyme that inhibits Akt activity in hepatic cell lines and diabetic rodent models (Chakraborty et al., 2010; 2012; Goshal et al., 2016).
Richie Barclay, Richard Mackenzie
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Insulin resistance in skeletal muscle contributes to whole body hyperglycaemia in pre‐diabetic and type 2 diabetic individuals. Insulin‐dependent glucose uptake in skeletal muscle requires the upregulation of the Akt‐AS160 signalling cascade (Bruss et al., 2005; Mackenzie & Elliott, 2014).
Jane Naufahu +8 more
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Inositol phosphate kinases in the eukaryote landscape [PDF]
Inositol phosphate encompasses a large multifaceted family of signalling molecules that originate from the combinatorial attachment of phosphate groups to the inositol ring. To date, four distinct inositol kinases have been identified, namely, IPK, ITPK,
Desfougères, Y +3 more
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Mammalian mitochondrial polyphosphate is regulated by the 5-InsP7synthase IP6K1
AbstractInorganic polyphosphate (polyP) is a linear polymer of varying length composed of phosphate residues linked by phosphoanhydride bonds. PolyP remains poorly understood in mammals due to its low abundance and lack of information on its synthesis and regulation.
Jayashree S. Ladke +8 more
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