Results 91 to 100 of about 1,062 (145)

Inositol phosphate pathway evolution and synthesis in Dictyostelium discoideum [PDF]

open access: yes, 2020
Inositol phosphates (InsPs) are polar water-soluble derivatives of the six- carbon cyclitol inositol. They are synthesized, through phosphorylation reactions, by kinases of four distinct families: IPK, IP5-2K, ITPK1 and PPIP5K, which are thought to be ...
Portela Torres, Paloma
core  

Inositol Pyrophosphates: Energetic, Omnipresent and Versatile Signalling Molecules [PDF]

open access: yes, 2017
Inositol pyrophosphates (PP-IPs) are a class of energy-rich signalling molecules found in all eukaryotic cells. These are derivatives of inositol that contain one or more diphosphate (or pyrophosphate) groups in addition to monophosphates.
A Burton   +130 more
core   +1 more source

Novel Regulatory Mechanisms Of Inositol Biosynthesis In Saccharomyces Cerevisiae And Mammalian Cells, And Implications For The Mechanism Underlying Vpa-Induced Glucose 6-Phosphate Depletion [PDF]

open access: yes, 2016
Myo-inositol is the precursor of all inositol containing molecules, including inositol phosphates, phosphoinositides and glycosylphosphatidylinositols, which are signaling molecules involved in many critical cellular functions.
Yu, Wenxi
core   +1 more source

ALOE VERA: AN ASSURED WEIGHT LOSS DIET – AN APPROACH TOWARD IMPROVING THE JUICE PALATABILITY AND IN SILICO ANALYSIS [PDF]

open access: yes, 2019
Objective: Obesity is an epidemic disease act as causative for global death. The principal aim of this study is to create an obesity treatment beverage that is palatable and readily acceptable to the public.
DISALVA X, MAHENDRAN RADHA, SHARANYA M
core   +1 more source

Inhibition of Inositol hexakisphosphate Kinase 1 (IP6K1) Does Not Increase Akt or mTOR Activity in vitro .

open access: yesThe FASEB Journal, 2018
Background Inositol hexakisphosphate Kinase 1 (IP6K1) has been identified as a key signalling enzyme that inhibits Akt activity in hepatic cell lines and diabetic rodent models (Chakraborty et al., 2010; 2012; Goshal et al., 2016).
Richie Barclay, Richard Mackenzie
openaire   +1 more source

High‐intensity Interval Exercise decreases IP6K1 Muscle Content & Improves Insulin Sensitivity (S I 2* ) in Pre‐diabetic Individuals

open access: yesThe FASEB Journal, 2018
Insulin resistance in skeletal muscle contributes to whole body hyperglycaemia in pre‐diabetic and type 2 diabetic individuals. Insulin‐dependent glucose uptake in skeletal muscle requires the upregulation of the Akt‐AS160 signalling cascade (Bruss et al., 2005; Mackenzie & Elliott, 2014).
Jane Naufahu   +8 more
openaire   +1 more source

Inositol phosphate kinases in the eukaryote landscape [PDF]

open access: yes, 2020
Inositol phosphate encompasses a large multifaceted family of signalling molecules that originate from the combinatorial attachment of phosphate groups to the inositol ring. To date, four distinct inositol kinases have been identified, namely, IPK, ITPK,
Desfougères, Y   +3 more
core  

Mammalian mitochondrial polyphosphate is regulated by the 5-InsP7synthase IP6K1

open access: yes
AbstractInorganic polyphosphate (polyP) is a linear polymer of varying length composed of phosphate residues linked by phosphoanhydride bonds. PolyP remains poorly understood in mammals due to its low abundance and lack of information on its synthesis and regulation.
Jayashree S. Ladke   +8 more
openaire   +1 more source

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