Results 111 to 120 of about 947 (141)
Some of the next articles are maybe not open access.
Nature Chemical Biology, 2008
Analyses of mutants affecting the synthesis of inositol phosphates have uncovered a variety of new roles for these small molecules in cells, but identification of their physiological targets has lagged behind. New studies on the yeast phosphate starvation response have brought the inositol pyrophosphate IP7 and its mechanism of action into sharp focus.
John D York, Daniel J Lew, York John D
exaly +2 more sources
Analyses of mutants affecting the synthesis of inositol phosphates have uncovered a variety of new roles for these small molecules in cells, but identification of their physiological targets has lagged behind. New studies on the yeast phosphate starvation response have brought the inositol pyrophosphate IP7 and its mechanism of action into sharp focus.
John D York, Daniel J Lew, York John D
exaly +2 more sources
Scientific Reports, 2016 AbstractFungal inositol polyphosphate (IP) kinases catalyse phosphorylation of IP3 to inositol pyrophosphate, PP-IP5/IP7, which is essential for virulence of Cryptococcus neoformans. Cryptococcal Kcs1 converts IP6 to PP-IP5/IP7, but the kinase converting IP5 to IP6 is unknown.
Cecilia Li +2 more
exaly +4 more sources
Oncometabolite 5-IP7 inhibits inositol 5-phosphatase to license E-cadherin endocytosis
Nature Chemical BiologyE-cadherin downregulation is an epithelial-mesenchymal transition hallmark canonically attributed to transcriptional repression. Here we delineate a metabolite-driven endocytic route of E-cadherin downregulation in inflammation-associated colorectal cancer (CRC).
Feng Rao, Peng Yifan, Anderson Karen E
exaly +3 more sources
2021
Six trial-trenches were laid out across the development site. The trenches were 20m long by 1.8m wide (totalling 216m) providing a 5% sample of the site. The trenches were mechanically excavated under archaeological supervision. All archaeological horizons were excavated and recorded according to the WSI.
Pooley, L., Hicks, E.
openaire +1 more source
Six trial-trenches were laid out across the development site. The trenches were 20m long by 1.8m wide (totalling 216m) providing a 5% sample of the site. The trenches were mechanically excavated under archaeological supervision. All archaeological horizons were excavated and recorded according to the WSI.
Pooley, L., Hicks, E.
openaire +1 more source
Protein Phophorylation Mechanism Involving IP7 Instead of ATP Holds Clues for New Drugs [PDF]
Cancer Biology and Therapy, 2005 exaly +2 more sources
Proceedings OPTO 2009 & IRS² 2009, 2009 1. Introdu ction In this paper a new method for calculation of heat power consumption in a heat exchanger is described. The method is based on the analysis of phenomena occurri ng on the ambient side. The calculation of heat power consumption represents an inverse heat transfer problem [1, 2]. In [3] an artificial neural network was used to approximate
Sebastian Dudzik, Waldemar Minkina
exaly +3 more sources
Archaeological evaluation on land at 1 Pykenham Way, Hadleigh, Suffolk, IP7 5EP
2021An archaeological evaluation (one trial-trench) was carried out at 1 Pykenham Way, Hadleigh, Suffolk in advance of the construction of a single detached dwelling and garage. The site is c 350m southwest of a significant multi-period site at Aldham Mill, is located in the main settlement area of medieval Hadleigh and surrounded by numerous recordings of
openaire +1 more source
Molecular Microbiology, 2021
AbstractDiphosphoinositol‐5‐pentakisphosphate (5‐PP‐IP5), also known as inositol heptakisphosphate (5‐IP7), has been described as a high‐energy phosphate metabolite that participates in the regulation of multiple cellular processes through protein binding or serine pyrophosphorylation, a posttranslational modification involving a β‐phosphoryl transfer.
Brian S. Mantilla +4 more
openaire +2 more sources
AbstractDiphosphoinositol‐5‐pentakisphosphate (5‐PP‐IP5), also known as inositol heptakisphosphate (5‐IP7), has been described as a high‐energy phosphate metabolite that participates in the regulation of multiple cellular processes through protein binding or serine pyrophosphorylation, a posttranslational modification involving a β‐phosphoryl transfer.
Brian S. Mantilla +4 more
openaire +2 more sources
Archaeological evaluation at Land at Powney Street, Milden, Milden, Suffolk, IP7 7AL: December 2022
2023Archaeological evaluation of two trial-trenches carried out as per the conditions laid out in the project brief and WSI An archaeological evaluation (two trial-trenches) was carried out on land at Powney Street, Milden, Suffolk in advance of the construction of two new dwellings.
openaire +1 more source