Cyclotides Isolated from an Ipecac Root Extract Antagonize the Corticotropin Releasing Factor Type 1 Receptor [PDF]
Cyclotides are plant derived, cystine-knot stabilized peptides characterized by their natural abundance, sequence variability and structural plasticity. They are abundantly expressed in Rubiaceae, Psychotrieae in particular.
Tognola, Carlotta +13 more
core +5 more sources
Reproductive studies on ipecac (Cephaelis ipecacuanha (Brot.) A. Rich; Rubiaceae): meiotic behavior and pollen viability [PDF]
Reproductive studies were carried out on Brazilian accessions of ipecac, Cephaelis ipecacuanha. Meiotic behavior was studied using the squashing technique.
T. N. S. Pereira +3 more
core +4 more sources
Poaia [Psychotria ipecacuanha (Brot.) Stoves]: aspectos da memória cultural dos poaieiros de Cáceres - Mato Grosso, Brasil Ipecac [Psychotria ipecacuanha (Brot.) Stoves]: aspects of cultural memory of "poaieiros" in Cáceres - Mato Grosso, Brazil [PDF]
O Brasil está entre os principais exportadores de poaia [Psychotria ipecacuanha (Brot.) Stoves] seguido do Panamá e Costa Rica. A poaia brasileira apresenta alto valor farmacológico das raízes devido aos teores de emetina e cefalina.
Ming, L.C. +6 more
core +3 more sources
Gene expression profiling before and after internode culture for adventitious shoot formation in ipecac. [PDF]
Background In ipecac (Carapichea ipecacuanha (Brot.) L. Andersson), adventitious shoots can be induced simply by placing internodal segments on phytohormone-free culture medium.
Okazaki K +6 more
europepmc +2 more sources
Mechanisms of antiviral action and toxicities of ipecac alkaloids: Emetine and dehydroemetine exhibit anti-coronaviral activities at non-cardiotoxic concentrations. [PDF]
The emergence of highly infectious pathogens with their potential for triggering global pandemics necessitate the development of effective treatment strategies, including broad-spectrum antiviral therapies to safeguard human health.
Sidorenko VS +24 more
europepmc +2 more sources
Dual effects of ipecac alkaloids with potent antiviral activity against foot-and-mouth disease virus as replicase inhibitors and direct virucides. [PDF]
Foot-and-Mouth Disease (FMD) is a contagious, blistering disease caused by the Foot-and-Mouth Disease virus (FMDV), which affects livestock globally. Currently, no commercial antiviral agent is available for effective disease control.
Pantanam A +6 more
europepmc +2 more sources
Cephaeline promotes ferroptosis by targeting NRF2 to exert anti-lung cancer efficacy. [PDF]
Context Cephaeline is a natural product isolated from ipecac (Cephaelis ipecacuanha [Brot.] A. Rich. [Rubiaceae]). It exhibits promising anti-lung cancer activity and ferroptosis induction may be a key mechanism for its anti-lung cancer effect.Objectives
Chen P, Ye Q, Liang S, Zeng L.
europepmc +2 more sources
Enantioselective Organocatalysis and Superacid Activation: Challenges and Opportunities
If chiral phosphoric acid catalysts are very efficient for the selective activation of basic substrates, such as imines or carbonyl compounds, the functionalization of non‐polarized C=C bonds, such as olefins or arenes, remained a stimulating goal for many years. This Concept article presents different smart strategies that have appeared throughout the
Bastien Michelet +4 more
wiley +1 more source
Medicating Georgia: Writing Doctors in the Old South
Abstract This essay looks at two medical families in Georgia between the eighteenth and nineteenth centuries, the Kollocks from Savannah and the Fort family from Milledgeville. Lemuel Kollock (1766–1823) moved there in 1792 from Connecticut to set up a medical practice.
Allan Ingram
wiley +1 more source
Family Planning and the Long Eighteenth‐Century Pocketbook
Abstract Eighteenth‐century medical literature recommended that women record their menstrual cycles to identify dates of conception, measure gestation, and predict delivery. Women's pocketbooks were natural repositories of such pregnancy‐related data. This article charts the history of women's pocketbooks providing printed affordances for menstruation,
Helen Williams
wiley +1 more source

