Results 11 to 20 of about 3,486 (152)

Discovery of a Plant Pictet-Spenglerase With R-Stereoselectivity. [PDF]

Angew Chem Int Ed Engl
Strictosidine synthases (STRs) are plant Pictet–Spenglerases catalyzing the coupling of a secoiridoid with tryptamine. All previously characterized strictosidine synthases are strictly S‐selective. Here, we report the discovery of Epi‐STR, an R‐selective STR ortholog from the medicinal plant Pogonopus speciosus.
Morweiser C, Heinicke S, O'Connor SE, Colinas M.   +3 more
europepmc   +2 more sources

Ectopic expression of LONELY GUY7 in epidermis of internodal segments for de novo shoot regeneration without phytohormone treatment in ipecac. [PDF]

Physiol Plant
Abstract In many plant species, the application of exogenous phytohormones is crucial for initiating de novo shoot regeneration. However, ipecac [Carapichea ipecacuanha (Brot) L. Andersson] has a unique ability to develop adventitious shoots on the epidermis of internodal segments without phytohormone treatment.
Okazaki K, Katano W, Shibata K, Asahina M, Koshiba-Takeuchi K, Shimomura K, Umehara M.   +6 more
europepmc   +2 more sources

Emetine dihydrochloride alleviated radiation‐induced lung injury through inhibiting EMT

Journal of Cellular and Molecular Medicine, Volume 27, Issue 23, Page 3839-3850, December 2023., 2023
Abstract Radiation‐induced lung injury (RILI), divided into early radiation pneumonia (RP) and late radiation‐induced pulmonary fibrosis (RIPF), is a common serious disease after clinical chest radiotherapy or nuclear accident, which seriously threatens the life safety of patients.
Xin Wang, Mo Li, Jizhong Yin, Jiayan Fang, Yimeng Ying, Tianxia Ye, Fangxiao Zhang, Shumei Ma, Hongran Qin, Xiaodong Liu   +9 more
wiley   +1 more source

Enantioselective Organocatalysis and Superacid Activation: Challenges and Opportunities

Chemistry – A European Journal, Volume 29, Issue 35, June 22, 2023., 2023
If chiral phosphoric acid catalysts are very efficient for the selective activation of basic substrates, such as imines or carbonyl compounds, the functionalization of non‐polarized C=C bonds, such as olefins or arenes, remained a stimulating goal for many years. This Concept article presents different smart strategies that have appeared throughout the
Bastien Michelet, Agnès Martin‐Mingot, Jean Rodriguez, Sébastien Thibaudeau, Damien Bonne   +4 more
wiley   +1 more source

Medicating Georgia: Writing Doctors in the Old South

Journal for Eighteenth-Century Studies, Volume 46, Issue 1, Page 153-166, March 2023., 2023
Abstract This essay looks at two medical families in Georgia between the eighteenth and nineteenth centuries, the Kollocks from Savannah and the Fort family from Milledgeville. Lemuel Kollock (1766–1823) moved there in 1792 from Connecticut to set up a medical practice.
Allan Ingram
wiley   +1 more source

Family Planning and the Long Eighteenth‐Century Pocketbook

Journal for Eighteenth-Century Studies, Volume 46, Issue 1, Page 113-133, March 2023., 2023
Abstract Eighteenth‐century medical literature recommended that women record their menstrual cycles to identify dates of conception, measure gestation, and predict delivery. Women's pocketbooks were natural repositories of such pregnancy‐related data. This article charts the history of women's pocketbooks providing printed affordances for menstruation,
Helen Williams
wiley   +1 more source

Regio‐ and Stereoselective Synthesis of Benzoquinolizidines

ChemistrySelect, Volume 7, Issue 9, March 7, 2022., 2022
Organocatalytic enantioselective domino Michael addition‐cyclization‐dehydration reactions and catalytic hydrogenation were carried to prepare benzo[c]quinolizidines with three contiguous chirality centers. The D2PM‐TMS showed the best performance with enantiomeric excess up to 95 %.
Anna Alekszi‐Kaszás, Klára Käfer‐Beke, Tamás R. Varga, Attila Bényei, Tibor Kovács, Attila Mándi, Tibor Kurtán, András Simon, Péter Nemes   +8 more
wiley   +1 more source

Current management of button battery injuries

Laryngoscope Investigative Otolaryngology, Volume 6, Issue 3, Page 549-563, June 2021., 2021
Abstract Button batteries (BB) are found in common household items and can lead to significant morbidity and mortality in the pediatric population when ingested. BBs are made of various chemistries and have a unique size and shape that yield significant injury when lodged in the pediatric esophagus.
Rishabh Sethia, Hannah Gibbs, Ian N. Jacobs, James S. Reilly, Keith Rhoades, Kris R. Jatana   +5 more
wiley   +1 more source

Coevolution as an engine of biodiversity and a cornucopia of ecosystem services

PLANTS, PEOPLE, PLANET, Volume 3, Issue 1, Page 61-73, January 2021., 2021
Coevolutionary processes, which have governed interactions between organisms throughout the history of life, also serve as an engine of ecosystem services for humans. The escalating arms races between plants and herbivores, flowers and pollinators, have generated a cornucopia of foods, raw materials, perfumes, spices, ornamentals, medicines, and drugs.
Robert A. Raguso
wiley   +1 more source

Alkaloids as Potential Phytochemicals against SARS‐CoV‐2: Approaches to the Associated Pivotal Mechanisms

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Since its inception, the coronavirus disease 2019 (COVID‐19) pandemic has infected millions of people around the world. Therefore, it is necessary to find effective treatments against Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2), as it is the viral source of COVID‐19.
Mohammad Bagher Majnooni, Sajad Fakhri, Gholamreza Bahrami, Maryam Naseri, Mohammad Hosein Farzaei, Javier Echeverría, Shih-Chao Lin   +6 more
wiley   +1 more source