Efficient search, mapping, and optimization of multi-protein genetic systems in diverse bacteria [PDF]
, 2014 Developing predictive models of multi-protein genetic systems to understand and optimize their behavior remains a combinatorial challenge, particularly when measurement throughput is limited.
Howard M Salis +6 more
core +2 more sources
Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli [PDF]
, 2010 Author Manuscript February 6, 2011Taxol (paclitaxel) is a potent anticancer drug first isolated from the Taxus brevifolia Pacific yew tree. Currently, cost-efficient production of Taxol and its analogs remains limited.
Ajikumar +35 more
core +1 more source
Impaired cardioprotective function of transplantation of mesenchymal stem cells from patients with diabetes mellitus to rats with experimentally induced myocardial infarction [PDF]
, 2013 BACKGROUND: Diabetes mellitus (DM) exacerbates coronary artery disease (CAD) morbidity and mortality. Mesenchymal stem cells (MSCs) play an important therapeutic role in myocardial ischemic injury.
Hui Jiang +6 more
core +1 more source
Production of tetra-methylpyrazine using engineered Corynebacterium glutamicum. [PDF]
, 2020 Corynebacterium glutamicum ATCC 13032 is an established and industrially-relevant microbial host that has been utilized for the expression of many desirable bioproducts.
Chen, Yan +8 more
core
Unravelling the potential of nitric acid as a surface modifier for improving the hemocompatibility of metallocene polyethylene for blood contacting devices [PDF]
, 2016 Design of blood compatible surfaces is obligatory to minimize platelet surface interactions and improve the thromboresistance of foreign surfaces when they are utilized as biomaterials particularly for blood contacting devices.
Jaganathan, Saravana Kumar +2 more
core +2 more sources
Identification of novel elements of the Drosophila blisterome sheds light on potential pathological mechanisms of several human diseases. [PDF]
, 2014 Main developmental programs are highly conserved among species of the animal kingdom. Improper execution of these programs often leads to progression of various diseases and disorders.
Bilousov, O. +3 more
core +3 more sources
BJU International, EarlyView.Objective To conduct a randomised controlled trial (RCT) to assess the efficacy of the Urethrotech urethral catheterisation device (UCD®; Urethrotech Ltd., Kingston Upon Thames, Surrey, UK) catheter compared to a standard Foley catheter for catheterisation in post‐phalloplasty transgender and gender diverse (TGD) individuals following urethral ...
Anastasia Frost +4 more
wiley +1 more source
Coenzyme Q10 deficiencies: pathways in yeast and humans. [PDF]
, 2018 Coenzyme Q (ubiquinone or CoQ) is an essential lipid that plays a role in mitochondrial respiratory electron transport and serves as an important antioxidant.
Awad, Agape M +5 more
core
Metabolic engineering of Ashbya gossypii for limonene production from xylose [PDF]
, 2022 BACKGROUND: Limonene is a cyclic monoterpene that has applications in the food, cosmetic, and pharmaceutical industries. The industrial production of limonene and its derivatives through plant extraction presents important drawbacks such as seasonal and ...
Buey, Rubén M. +3 more
core +1 more source
Advances in Erectile Dysfunction Management: What Does Work
Trends in Urology &Men's Health, Volume 17, Issue 3, June 2026.ABSTRACT Erectile dysfunction (ED) is a prevalent and multifactorial disorder that substantially affects quality of life. Pathophysiology includes vascular, neurogenic, drug‐induced, and psychogenic causes, and frequently coexists with cardiometabolic disease.
Jolie Shen +3 more
wiley +1 more source