Results 31 to 40 of about 2,400 (132)

Plastoquinone and Ubiquinone in Plants: Biosynthesis, Physiological Function and Metabolic Engineering [PDF]

, 2016
Plastoquinone (PQ) and ubiquinone (UQ) are two important prenylquinones, functioning as electron transporters in the electron transport chain of oxygenic photosynthesis and the aerobic respiratory chain, respectively, and play indispensable roles in ...
Miaomiao Liu, Shanfa Lu
core   +2 more sources

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

Advanced Science, Volume 13, Issue 21, 13 April 2026.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng, Hao Liu, Haolin Han, Meng Meng, Shaojie Wang, Tianwei Tan, Haijia Su   +6 more
wiley   +1 more source

Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum [PDF]

, 2013
The antimalarial agent fosmidomycin is a validated inhibitor of the nonmevalonate isoprenoid biosynthesis (methylerythritol 4-phosphate [MEP]) pathway in the malaria parasite, Plasmodium falciparum.
Hodge, Dana, Howe, Ruth, Jimah, John, Kelly, Megan, Odom, Audrey R   +4 more
core   +2 more sources

Microbial production of advanced biofuels [PDF]

, 2021
Concerns over climate change have necessitated a rethinking of our transportation infrastructure. One possible alternative to carbon-polluting fossil fuels are biofuels produced from a renewable carbon source using engineered microorganisms. Two biofuels,
Garcia Martin, H., Keasling, J., Lee, T, Mukhopadhyay, A., Singer, S., Sundstrom, E.   +5 more
core   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

An investigation into the effects of commencing haemodialysis in the critically ill [PDF]

, 2012
<b>Introduction:</b> We have aimed to describe haemodynamic changes when haemodialysis is instituted in the critically ill. 3 hypotheses are tested: 1)The initial session is associated with cardiovascular instability, 2)The initial ...
Docking, R., Kinsella, J., Moss, L., Sim, M., Sleeman, D.   +4 more
core   +2 more sources

Biological Activities of Essential Oils: From Plant Chemoecology to Traditional Healing Systems [PDF]

, 2017
Essential oils are complex mixtures of hydrocarbons and their oxygenated derivatives arising from two different isoprenoid pathways. Essential oils are produced by glandular trichomes and other secretory structures, specialized secretory tissues mainly ...
Ademiluyi, Adedayo Oluwaseun, Ayatollahi, Seyed Abdulmajid, Daglia, Maria, Iriti, Marcello, Loizzo, Monica R, Sharifi-Rad, Javad, Sharifi-Rad, Marzieh, Sharifi-Rad, Mehdi, Sharifi-Rad, Razieh, Sureda, Antoni, Tenore, Gian Carlo, Tundis, Rosa, Valussi, Marco   +12 more
core   +3 more sources

A global perspective on carotenoids: metabolism, biotechnology, and benefits for nutrition and health. [PDF]

, 2018
Carotenoids are lipophilic isoprenoid compounds synthesized by all photosynthetic organisms and some non-photosynthetic bacteria and fungi. With some notable exceptions, animals (including humans) do not produce carotenoids de novo but take them in ...
Bonet Piña, María Luisa, Boronat Margosa, Albert, Gómez Gómez, Lourdes, Hornero Méndez, Dámaso, Limón Mirón, María del Carmen, Meléndez Martínez, Antonio Jesús, Olmedilla Alonso, Begoña, Rodríguez Concepción, Manuel, Ávalos Cordero, Francisco Javier   +8 more
core   +1 more source

Metabolome and Transcriptome Profiling of Chicory Roots Provide Insights Into Laticifer Development and Specialized Metabolism

Physiologia Plantarum, Volume 178, Issue 1, January/February 2026.
ABSTRACT Chicory roots produce inulin, a dietary fiber, as well as large quantities of bitter sesquiterpene lactones (STLs), which have valuable biological activities. In an effort to understand the compartmentalization of metabolism within chicory roots and the molecular basis of the development of laticifers that produce the chicory latex, we ...
Khabat Vahabi, Gerd U. Balcke, Johanna C. Hakkert, Ingrid M. van der Meer, Benedikt Athmer, Alain Tissier   +5 more
wiley   +1 more source

Hormetic Effects of 7‐Ketocholesterol in Preventing Ferroptosis in Hepatocytes

Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
Background and Aims Ferroptosis, a form of cell death marked by iron dysregulation and lipid peroxidation, has been implicated in liver and neurodegenerative diseases. 7‐ketocholesterol (7KC), a cholesterol oxidation product, induces oxidative stress and inflammation at high concentrations.
Sarit Anavi, Nicole Giltman, Haim Zeigerman, Zecharia Madar, Oren Tirosh, Liang-Jun Yan   +5 more
wiley   +1 more source