Isopentenyl diphosphate (IPP)-bypass mevalonate pathways for isopentenol production [PDF]
, 2020 a b s t r a c t Branched C 5 alcohols are promising biofuels with favorable combustion properties. A mevalonate (MVA)-based isoprenoid biosynthetic pathway for C 5 alcohols was constructed in Escherichia coli using genes from several organisms, and the ...
Aram Kang +5 more
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Plant Biotechnology Journal, Volume 23, Issue 9, Page 4158-4174, September 2025.Summary Schizonepeta tenuifolia Briq. (S. tenuifolia) is a traditional Chinese medicinal plant widely used to treat colds, fever and respiratory diseases. Volatile oils including the monoterpenoids limonene, pulegone and menthone are major constituents of S. tenuifolia that determine its medicinal value and consumer popularity.
Man Zhang +7 more
wiley +1 more source
The replisome-coupled E3 ubiquitin ligase Rtt101Mms22 counteracts Mrc1 function to tolerate genotoxic stress [PDF]
, 2016 Faithful DNA replication and repair requires the activity of cullin 4-based E3 ubiquitin ligases (CRL4), but the underlying mechanisms remain poorly understood.
Buser, Raymond +12 more
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Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition
Immunology, Volume 175, Issue 3, Page 300-322, July 2025.Mevalonate pathway is important for the effector function of gammadelta T cells. Inhibition of the pathway in vivo and in vitro impairs cytokine and cytotoxic molecule production by mainly affecting protein prenylation and disturbing intracellular signalling in Vdelta2 T cells. Created with Biorender.
Tsz Kin Suen +14 more
wiley +1 more source
The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation [PDF]
, 2018 Background: Acute kidney injury (AKI) is highly prevalent in hospital inpatient populations, leading to significant mortality and morbidity, reduced quality of life and high short- and long-term health-care costs for the NHS.
Cairns, DA +11 more
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Mutations in escherichia coli aceE and ribB genes allow survival of strains defective in the first step of the isoprenoid biosynthesis pathway [PDF]
, 2019 A functional 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway is required for isoprenoid biosynthesis and hence survival in Escherichia coli and most other bacteria.
Baidoo, Edward E.K. +9 more
core +1 more source
Bioengineering studies and pathway modeling of the heterologous biosynthesis of tetrahydrocannabinolic acid in yeast [PDF]
, 2020 Heterologous biosynthesis of tetrahydrocannabinolic acid (THCA) in yeast is a biotechnological process in Natural Product Biotechnology that was recently introduced. Based on heterologous genes from Cannabis sativa and Streptomyces spp.
Kayser, Oliver +2 more
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Prenol production in a microbial host via the “Repass” Pathways [PDF]
Prenol and isoprenol are promising advanced biofuels and serve as biosynthetic precursors for pharmaceuticals, fragrances, and other industrially relevant compounds.
Carruthers, David N +4 more
core +1 more source
Host adapted serotypes of Salmonella enterica [PDF]
, 2000 Salmonella constitutes a genus of zoonotic bacteria of worldwide economic and health importance. The current view of salmonella taxonomy assigns the members of this genus to two species: S. enterica and S. bongori. S.
Bernard, Serge +8 more
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