Results 41 to 50 of about 4,447 (126)

Volatile‐Mediated Plant Defense Networks: Field Evidence for Isoprene as a Short‐Distance Immune Signal

open access: yesPlant, Cell &Environment, Volume 48, Issue 12, Page 8616-8629, December 2025.
ABSTRACT Isoprene, the most abundant biogenic hydrocarbon in the atmosphere, is known to protect photosynthesis from abiotic stress and significantly impact atmospheric chemistry. While laboratory studies show that isoprene can enhance plant immunity, its role in plant‐plant communication under natural field conditions remains unclear.
Peiyuan Zhu   +7 more
wiley   +1 more source

Destabilization of macrophage migration inhibitory factor by 4‐IPP reduces NF‐κB/P‐TEFb complex‐mediated c‐Myb transcription to suppress osteosarcoma tumourigenesis

open access: yes, 2022
Background As an inflammatory factor and oncogenic driver protein, the pleiotropic cytokine macrophage migration inhibitory factor (MIF) plays a crucial role in the osteosarcoma microenvironment.
Zhenhua Feng   +14 more
core   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

open access: yesMicrobial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin   +3 more
wiley   +1 more source

Mechanistic Characterisation of a Diterpene Synthase for Chryseojoostenes A–E from Chryseobacterium Joostei

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 43, October 20, 2025.
The bacterial diterpene synthase CjCS for chryseojoostenes was mechanistically characterised through labelling experiments, density functional theory (DFT) calculations, and conversion of substrate analogs with blocked reactivity. Site‐directed mutagenesis gave access to minor enzyme products, including chryseojoostene E, whose biosynthesis involves a ...
Georges B. Tabekoueng   +5 more
wiley   +1 more source

Breast Cancer: Molecular Pathogenesis and Targeted Therapy

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Dysregulation signaling pathways in various breast cancer subtypes and their targeting using different inhibitors. ABSTRACT Breast cancer (BC) is the most prevalent cancer in women and remains the leading cause of cancer‐related mortality globally.
Md Abdus Samad   +9 more
wiley   +1 more source

Natural rubber biosynthesis pathway in plants.

open access: yes
The monomer isopentenyl pyrophosphate (IPP) is derived from two sources: the mevalonic acid (MVA) pathway and the methylerythritol (MEP) pathway. IPP is converted to dimethylallyl pyrophosphate (DMAPP) by IPP-isomerase. DMAPP and IPP are then polymerized
Meisam Zargar (17827351)   +5 more
core   +1 more source

The regulation of the cAMP signalling pathway in the human pathogenic fungus Paracoccidioides brasiliensis [PDF]

open access: yes, 2008
Paracoccidioides brasiliensis (Pb) is the causative agent of the disease Paracoccioidomycosis (PCM), which is one of the most prevalent systemic mycoses in Latin Amercia (Borges-Walmsley et al., 2002). P.
Janganan, Thamarai kannan
core  

Fasciculoventricular accessory pathway : a misleading and unusual bypass tract [PDF]

open access: yes, 2010
We present the case of a 25 year-old man referred for an electrophysiological study due to suspected pre-excitation as the cause of two recent syncopal episodes.
Kukla, Piotr, Jastrzębski, Marek
core   +2 more sources

Stable platelet production via the bypass pathway explains long-term hematopoietic stem cell reconstitution

open access: yes
Summary: In vivo differentiation pathways into several blood cell lineages of Hematopoietic stem cells (HSCs) remain challenging to track over time.
Hiromitsu Nakauchi   +9 more
core   +1 more source

Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli

open access: yes, 2000
An alternative mevalonate-independent pathway for isoprenoid biosynthesis has been recently discovered in eubacteria (including Escherichia coli) and plant plastids, although it is not fully elucidated yet. In this work, E.
Maldonado, Carlos   +7 more
core   +2 more sources

Home - About - Disclaimer - Privacy