Results 41 to 50 of about 2,400 (132)

Measurement and clinical significance of biomarkers of oxidative stress in humans [PDF]

open access: yes, 2017
Oxidative stress is the result of the imbalance between reactive oxygen species (ROS) formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are relevant in the evaluation of the disease status and of the health-enhancing ...
Altieri, Fabio   +2 more
core   +3 more sources

Volatile‐Mediated Plant Defense Networks: Field Evidence for Isoprene as a Short‐Distance Immune Signal

open access: yesPlant, Cell &Environment, Volume 48, Issue 12, Page 8616-8629, December 2025.
ABSTRACT Isoprene, the most abundant biogenic hydrocarbon in the atmosphere, is known to protect photosynthesis from abiotic stress and significantly impact atmospheric chemistry. While laboratory studies show that isoprene can enhance plant immunity, its role in plant‐plant communication under natural field conditions remains unclear.
Peiyuan Zhu   +7 more
wiley   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

open access: yesMicrobial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin   +3 more
wiley   +1 more source

Day and night heat stress trigger different transcriptomic responses in green and ripening grapevine (vitis vinifera) fruit [PDF]

open access: yes, 2014
Background: Global climate change will noticeably affect plant vegetative and reproductive development. The recent increase in temperatures has already impacted yields and composition of berries in many grapevine-growing regions.
Chatbanyong, Ratthaphon   +6 more
core   +2 more sources

Mechanistic Characterisation of a Diterpene Synthase for Chryseojoostenes A–E from Chryseobacterium Joostei

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 43, October 20, 2025.
The bacterial diterpene synthase CjCS for chryseojoostenes was mechanistically characterised through labelling experiments, density functional theory (DFT) calculations, and conversion of substrate analogs with blocked reactivity. Site‐directed mutagenesis gave access to minor enzyme products, including chryseojoostene E, whose biosynthesis involves a ...
Georges B. Tabekoueng   +5 more
wiley   +1 more source

Breast Cancer: Molecular Pathogenesis and Targeted Therapy

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Dysregulation signaling pathways in various breast cancer subtypes and their targeting using different inhibitors. ABSTRACT Breast cancer (BC) is the most prevalent cancer in women and remains the leading cause of cancer‐related mortality globally.
Md Abdus Samad   +9 more
wiley   +1 more source

A Comprehensive Review on Anxiolytic Effect of Lavandula Angustifolia Mill. in Clinical Studies

open access: yesFood Science &Nutrition, Volume 13, Issue 9, September 2025.
Lavender has been traditionally used as a medicinal herb to relieve stress and anxiety. Linalool and linalyl acetate are the main bioactives, along with terpenes and alcohols. Lavender modulates receptors and neurotransmitters to downregulate the excitation. Neuroplasticity is restored via signaling cascades and calcium channels.
Sana Manzoor   +6 more
wiley   +1 more source

多細胞生物におけるrRNAのm1A修飾に関する研究 [PDF]

open access: yes, 2018
この博士論文は内容の要約のみの公開(または一部非公開)になっています筑波大学 (University of Tsukuba ...
YOKOYAMA Wataru, 横山 航
core   +1 more source

The key glycolytic enzyme phosphofructokinase is involved in resistance to antiplasmodial glycosides [PDF]

open access: yes, 2020
Plasmodium parasites rely heavily on glycolysis for ATP production and for precursors for essential anabolic pathways, such as the methylerythritol phosphate (MEP) pathway.
Andrews, Katherine T   +14 more
core   +3 more sources

Ferroptosis in Haematological Malignancies: From Regulatory Networks to Novel Therapeutic Opportunities

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 17, September 2025.
ABSTRACT Haematological malignancies encompass a wide spectrum of blood cell disorders with diverse prognoses. Despite recent advances in therapy, many of these disorders remain incurable or exhibit relapse and drug resistance. Ferroptosis, an iron‐dependent form of cell death caused by lipid peroxidation, holds promise as a strategy to overcome the ...
Maryam Shayanmanesh   +2 more
wiley   +1 more source

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