Results 11 to 20 of about 693 (87)
Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host. [PDF]
ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
Cimini E +4 more
europepmc +2 more sources
Chemoenzymatic Synthesis of (4R,7R)‐Zingiberene Enables Construction of nor‐Sesquiterpene Semiochemical Analogs [PDF]
A five‐enzyme chemoenzymatic synthesis of the insect‐repellent (4R,7R)‐zingiberene from the wild tomato (Solanum habrochaites) has been developed. This approach enabled the elucidation of the sesquiterpene synthase cyclization mechanism of (2Z,6Z)‐farnesyl pyrophosphate and bypasses classic biosynthetic constraints of prenyltransferase chain extension ...
Johnson L +6 more
europepmc +2 more sources
Ferroptosis: Newly Emerged Regulator for Human Disease. [PDF]
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Xiao D, Ye L, Jiang T, Liu M, Zhou Y.
europepmc +2 more sources
Genome-scale Metabolic Modeling Guided Escherichia coli Engineering for De Novo Biosynthesis of Chrysanthemic Acid. [PDF]
Genome‐scale metabolic modeling is preceded to the engineered E. coli cell factory for the de novo biosynthesis of biopesticide chrysanthemic acid. The debranching strategy redirects metabolic flux, enhancing precursor and target compound production.
Yu J +6 more
europepmc +2 more sources
Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms. [PDF]
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Du S +9 more
europepmc +2 more sources
Objective To conduct a randomised controlled trial (RCT) to assess the efficacy of the Urethrotech urethral catheterisation device (UCD®; Urethrotech Ltd., Kingston Upon Thames, Surrey, UK) catheter compared to a standard Foley catheter for catheterisation in post‐phalloplasty transgender and gender diverse (TGD) individuals following urethral ...
Anastasia Frost +4 more
wiley +1 more source
Lipid membranes are fundamental to all prokaryotic life. Besides acting as barrier, by orienting as hydrophobic bilayer, lipids are involved in a wide variety of other cellular processes. As a consequence, prokaryotic membranes are dynamic entities that switch their lipid composition as required; a process that requires tight interplay with the lipid ...
Sergiy Gan, Marten Exterkate
wiley +1 more source
Nonthermal plasma approaches for combating implant‐associated infections: A compendious review
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe +8 more
wiley +1 more source
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source

