Earthquake and tsunami potential levels in Sulawesi (lesson learned earthquake West Sulawesi) [PDF]
E3S Web of Conferences, 2021 Earthquake and tsunami disasters always bring negative impacts and losses for humans. The high frequency of earthquake disasters in Sulawesi and the massive impact of destruction and damage to infrastructure, loss of homes and property, and death of ...
Khoirudin Apriyadi Rio +3 more
doaj +1 more source
ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cells- derived motoneurons [PDF]
, 2015 Patient-derived induced Pluripotent Stem Cells (iPSCs) provide an opportunity to study human diseases mainly in those cases where no suitable model systems are available.
Bozzoni, Irene +9 more
core +4 more sources
Translational Neurodegeneration, 2023 Background Alzheimer’s disease (AD) is the most common neurodegenerative disorder in the elderly, resulting in gradual destruction of cognitive abilities.
Hyunkyung Mo +7 more
doaj +1 more source
Maturing iPSC-Derived Cardiomyocytes [PDF]
Cells, 2020 Cardiovascular disease is a major cause of mortality worldwide [...]
openaire +3 more sources
Induced pluripotent stem cells, a giant leap for mankind therapeutic applications [PDF]
, 2019 Induced pluripotent stem cells (iPSC) technology has propelled the field of stem cells biology, providing new cells to explore the molecular mechanisms of pluripotency, cancer biology and aging.
Bragança, José +3 more
core +1 more source
Anti-fibrotic effect of a selective estrogen receptor modulator in systemic sclerosis
Stem Cell Research & Therapy, 2022 Background The rarity of systemic sclerosis (SSc) has hampered the development of therapies for this intractable autoimmune disease. Induced pluripotent stem cell (iPSC) can be differentiated into the key disease-affected cells in vitro.
Yena Kim +3 more
doaj +1 more source
Improving food security through the urban farming workshop for disaster risk reduction: evidence from Jogoyudan Village, Yogyakarta as a Resilient City [PDF]
E3S Web of Conferences, 2021 This study aims to determine the effect of the implementation of urban farming workshops on food security of Jogoyudan Village residents supporting the concept of Yogyakarta as a Resilient City as a disaster risk reduction.
Jalu Aji Lexi +4 more
doaj +1 more source
Copy number variations in healthy subjects. Case study: iPSC line CSSi005-A (3544) production from an individual with variation in 15q13.3 chromosome duplicating gene CHRNA7 [PDF]
, 2018 CHRNA7, encoding the neuronal alpha7 nicotinic acetylcholine receptor (a7nAChR), is highly expressed in the brain, particularly in the hippocampus. It is situated in the 15q13.3 chromosome region, frequently associated with a Copy Number Variation (CNV),
Altieri, Filomena +13 more
core +1 more source
Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease. [PDF]
, 2019 The MHC region is highly associated with autoimmune and infectious diseases. Here we conduct an in-depth interrogation of associations between genetic variation, gene expression and disease.
Aguiar +76 more
core +2 more sources
Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination [PDF]
, 2017 Effective bidirectional signalling between axons and Schwann cells is essential for both the development and maintenance of peripheral nerve function. We have established conditions by which human induced pluripotent stem cell-derived sensory neurons can
Bennett, David L.H. +5 more
core +2 more sources