Results 31 to 40 of about 975,688 (225)

Anti-tumor effect of mitochondrial targeted small molecule IR-780 on cisplatin-resistant bladder cancer cells

Di-san junyi daxue xuebao, 2021
Objective To study the anti-tumor effect of IR-780, a mitochondrial targeting small molecule, on cisplatin-resistant T24 cell line (T24/DPP). Methods T24/DPP cell line was constructed by repeated and discontinuous stimulation of T24 cells with cisplatin.
HUANG Yuandi, SHEN Chongxing, LI Jinjin, FANG Qiang, ZHI Yi   +4 more
doaj   +2 more sources

Selective and Sensitive Dual Chromogenic Cyanide and Fluorescent Azide Probe

Photochem
IR-780 is a heptamethine cyanine dye that exhibits strong absorbance in the near-infrared region. Herein, we report IR-780 dye as a dual sensor for chromogenic cyanide detection and azide’s fluorogenic sensing in acetonitrile. Cyanide and hydroxide cause
Yousef M. Hijji, Rajeesha Rajan, Amjad M. Shraim, Bassam Attili, Sisay Uota, Fasil Abebe   +5 more
doaj   +2 more sources

Biomimetic biomineralization nanoplatform-mediated differentiation therapy and phototherapy for cancer stem cell inhibition and antitumor immunity activation

Asian Journal of Pharmaceutical Sciences, 2023
Growing evidence suggests that the presence of cancer stem cells (CSCs) is a major challenge in current tumor treatments, especially the transition from non-CSCs to differentiation of CSCs for evading conventional therapies and driving metastasis.
Shan Gao, Meng Liu, Dongzhu Liu, Xinru Kong, Yuelin Fang, Yingying Li, Hang Wu, Jianbo Ji, Xiaoye Yang, Guangxi Zhai   +9 more
doaj   +2 more sources

Synthesis of IR-780 dye-conjugated abiraterone for prostate cancer imaging and therapy

International Journal of Oncology, 2016
Near-infrared fluorescence (NIRF) imaging is a novel imaging modality that allows for detection and real‑time monitoring of various pathophysiological states. IR-780 iodide has been used as an ideal platform to construct theranostic agents for cancer imaging and therapy.
Xiaomin, Yi, Jingfang, Zhang, Fei, Yan, Zifan, Lu, Jiaoti, Huang, Chongxian, Pan, Jiarui, Yuan, Wanxiang, Zheng, Keke, Zhang, Di, Wei, Wei, He, Jianlin, Yuan   +11 more
openaire   +4 more sources

Enhanced Modulation of Terahertz Generation in Optically Pumped Silicon-Based CoFeB/Ir Heterostructures [PDF]

Nanomaterials
Silicon-compatible spintronic terahertz emitters (STEs) are crucial for on-chip ultrafast optoelectronic integration, yet their all-optical controllability remains a key challenge.
Ruijie Peng, Zuanming Jin, Yexing Jiang, Huiping Zhang, Wei He, Yan Peng   +5 more
doaj   +2 more sources

Coupling the near-infrared fluorescent dye IR-780 with cabazitaxel makes renal cell carcinoma chemotherapy possible

Biomedicine & Pharmacotherapy, 2019
Renal cell carcinoma (RCC) has always been considered resistant to chemotherapy. IR-780 is a near-infrared fluorescent (NIRF) dye that can be efficiently taken up by RCC cells. Cabazitaxel is a cytotoxic drug that interferes with mitosis by acting on tubulin.
Yu, Zheng, Ting, Lan, Di, Wei, Geng, Zhang, Guangdong, Hou, Jiarui, Yuan, Fei, Yan, Fuli, Wang, Ping, Meng, Xiaojian, Yang, Guo, Chen, Zheng, Zhu, Zifan, Lu, Wei, He, Jianlin, Yuan   +14 more
openaire   +3 more sources

Design of an Amphiphilic Poly(aspartamide)-mediated Self-assembled Nanoconstruct for Long-Term Tumor Targeting and Bioimaging

Molecules, 2019
Biodegradable polymers have been developed for the targeted delivery of therapeutics to tumors. However, tumor targeting and imaging are usually limited by systemic clearance and non-specific adsorption.
Kondareddy Cherukula, Saji Uthaman, In-Kyu Park   +2 more
doaj   +2 more sources

Photostability Highly Improved Nanoparticles Based on IR-780 and Negative Charged Copolymer for Enhanced Photothermal Therapy

ACS Biomaterials Science & Engineering, 2018
The development of near-infrared (NIR) dyes with desirable photophysical characteristics for tumor therapy is highly expected at present. In this report, IR-780 iodide was loaded by the mercaptopropionic acid grafted poly(ethylene glycol)-block-poly(ε-caprolactone)-block-poly(allyl glycidyl ether) [mPEG5K-PCL10K-PAGE6 (MPA)] copolymer to form ...
Nannan Shao, Yanxin Qi, Hongtong Lu, Dongyun He, Bin Li, Yubin Huang   +5 more
openaire   +3 more sources

Multi-pathway oxidative stress amplification via controllably targeted nanomaterials for photoimmunotherapy of tumors [PDF]

Journal of Nanobiotechnology
Photoimmunotherapy, which combines phototherapy with immunotherapy, exhibits significantly improved therapeutic effects compared with mono-treatment regimens.
Song Li, Yunheng Liu, Xiaokang Zhang, Yurong Liu, Longqing Si, Shaojing Jiang, Aoya Wang, Xukai Che, Jing Chen, Jinghui Hu   +9 more
doaj   +2 more sources

Evaluating Feature-Based Homography Pipelines for Dual-Camera Registration in Acupoint Annotation [PDF]

Journal of Imaging
Reliable acupoint localization is essential for developing artificial intelligence (AI) and extended reality (XR) tools in traditional Korean medicine; however, conventional annotation of 2D images often suffers from inter- and intra-annotator ...
Thathsara Nanayakkara, Hadi Sedigh Malekroodi, Jaeuk Sul, Chang-Su Na, Myunggi Yi, Byeong-il Lee   +5 more
doaj   +2 more sources