Results 1 to 10 of about 2,657,421 (309)

Polymer Nanoparticle-Based Photodynamic Therapy Combined with Immunotherapy for Solid Tumor Treatment

Current Issues in Molecular Biology
Polymer nanoparticles have been widely studied for tumor treatment due to their excellent biocompatibility, structural diversity, and multi-functionality.
Jieling Lao, Qiuting Ye, Shijie Fan, Zhengqing Cheng, Pan Wu   +4 more
doaj   +1 more source

Neutrophil Extracellular Traps in Cancer Metastasis: From Mechanistic Understanding to Targeted Therapy

Current Oncology
Metastasis is the leading cause of cancer-related death, underscoring the need to elucidate the key mechanisms behind this process. Neutrophil extracellular traps (NETs) have emerged as critical regulators of tumor progression and metastasis. This review
Xiaorui Tian, Jintong Na, Xinyi Tan, Fengqiu Dang, Rui Zhu, Liping Zhong, Yongxiang Zhao   +6 more
doaj   +1 more source

Oxidative Stress on the Ground and in the Microgravity Environment: Pathophysiological Effects and Treatment

Antioxidants
With the continued exploration of the universe, there is an increasingly urgent need to address the health challenges arising from spaceflight. In space, astronauts are exposed to radiation, confinement and isolation, circadian rhythm dysregulation, and ...
Xinyuan Zhang, Huaiying Zhu, Jinhua Zhang   +2 more
doaj   +1 more source

The Role of CD4⁺ T Helper Cell Subsets in Hepatocellular Carcinoma: Implications for Tumour Progression and Immunotherapy

Cells
Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related mortality; its progression is strongly linked to the liver’s immune microenvironment.
Jijie Shao, Jintong Na, Honghua Huang, Lei Xiao, Fengqiu Dang, Rongshun Zheng, Liping Zhong, Yongxiang Zhao   +7 more
doaj   +1 more source

Research on the Hippo Pathway in Cancer

Cells
The Hippo, as a central pathway regulating cell proliferation, apoptosis, stem cell homeostasis and organ development, is closely associated with the onset and progression of tumors, metabolic reprogramming, drug resistance and immune evasion when it is ...
Fengqiu Dang, Shuhuan Dai, Tianqi Zhao, Rong Zhang, Long Chen, Yongxiang Zhao   +5 more
doaj   +1 more source

Multi-Pathway Study for Oxaliplatin Resistance Reduction

Current Issues in Molecular Biology
Chemotherapy for cancer frequently uses platinum-based medications, including oxaliplatin, carboplatin, and cisplatin; however, due to their high systemic toxicity, lack of selectivity, drug resistance, and other side effects, platinum-based medications ...
Tong Ye, Chen Wu, Jintong Na, Xiyu Liu, Yong Huang   +4 more
doaj   +1 more source

Advances and challenges of sonodynamic nanomedicines for deep seated tumor therapy

Discover Oncology
Sonodynamic therapy (SDT) has become a promising, noninvasive treatment modality with deep tissue penetration and precise controllability, offering a new approach for cancer treatment. Nanotechnology improves stability, targeting ability, and therapeutic
Jinlong Zhao, Yongxiang Zhao
doaj   +1 more source

Microneedle-Enabled Exosome Therapy: From Tumor Targeting to Precision Treatment of Complex Diseases. [PDF]

Int J Nanomedicine
Fang Y, Song H, Li D, Jiang Y, Zhao K, Qiu X, Zhao C, Yu X, Li Y, Song X.   +9 more
europepmc   +1 more source

Integrating Tumor Targeting and Half-Life Extension into a Dual-Surfaced Single-Domain ADAPT Protein. [PDF]

Mol Pharm
Larsson E, Ud-Din M, Bitzios A, Recasens Pérez-Vera E, Tegel H, Orlova A, Tolmachev V, Vorobyeva A, Hober S.   +8 more
europepmc   +1 more source

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death. [PDF]

Int J Mol Med
Liu J, Guo W, Li J, Li X, Geng J, Chen Q, Gao J.   +6 more
europepmc   +1 more source