Results 11 to 20 of about 755,200 (268)

Tumor Evolution as a Therapeutic Target [PDF]

open access: yesCancer Discovery, 2017
Abstract Recent technological advances in the field of molecular diagnostics (including blood-based tumor genotyping) allow the measurement of clonal evolution in patients with cancer, thus adding a new dimension to precision medicine: time.
Amirouchene-Angelozzi, Nabil   +2 more
openaire   +3 more sources

Autophagy-mediated nanomaterials for tumor therapy

open access: yesFrontiers in Oncology, 2023
Autophagy is a lysosomal self-degradation pathway that plays an important protective role in maintaining intracellular environment. Deregulation of autophagy is related to several diseases, including cancer, infection, neurodegeneration, aging, and heart
Zijian Liao   +6 more
doaj   +1 more source

A Dual Targeting Magnetic Nanoparticle for Human Cancer Detection

open access: yesNanoscale Research Letters, 2019
Malignant tumors are a major threat to human life and high lymphatic vessel density is often associated with metastatic tumors. With the discovery of molecules targeted at the lymphatic system such as lymphatic vessel endothelial hyaluronan receptor 1 ...
Siwen Wu   +9 more
doaj   +1 more source

Research progress of nanovaccine in anti-tumor immunotherapy

open access: yesFrontiers in Oncology, 2023
Tumor vaccines aim to activate dormant or unresponsive tumor-specific T lymphocytes by using tumor-specific or tumor-associated antigens, thus enhancing the body’s natural defense against cancer. However, the effectiveness of tumor vaccines is limited by
Min Yao   +7 more
doaj   +1 more source

Targeting tumor resistance mechanisms [PDF]

open access: yesFaculty Reviews, 2021
Cancer develops resistance to treatments through many mechanisms. Single-cell analyses reveal the intratumor heterogeneity and dynamic relationships between cancer cell subpopulations. These analyses also highlight that various mechanisms of resistance may coexist in a given tumor.
Gerard, Louise   +2 more
openaire   +2 more sources

A Graphene Oxide-Based Fluorescent Aptasensor for the Turn-on Detection of CCRF-CEM

open access: yesNanoscale Research Letters, 2018
A convenient, low-cost, and highly sensitive fluorescent aptasensor for detection of leukemia has been developed based on graphene oxide-aptamer complex (GO-apt).
Jie Tan   +11 more
doaj   +1 more source

Aptamer Combined with Fluorescent Silica Nanoparticles for Detection of Hepatoma Cells

open access: yesNanoscale Research Letters, 2017
Purpose The purpose of this study is to develop a simple, effective method to label hepatoma cells with aptamers and then detect them using fluorescent silica nanoparticles (FSNPs).
Zixi Hu   +12 more
doaj   +1 more source

Identification of co-expression hub genes for ferroptosis in kidney renal clear cell carcinoma based on weighted gene co-expression network analysis and The Cancer Genome Atlas clinical data

open access: yesScientific Reports, 2022
Renal clear cell carcinoma (KIRC) is one of the most common tumors worldwide and has a high mortality rate. Ferroptosis is a major mechanism of tumor occurrence and development, as well as important for prognosis and treatment of KIRC. Here, we conducted
Shengxian Li   +3 more
doaj   +1 more source

Reversing the Tumor Target: Establishment of a Tumor Trap [PDF]

open access: yesFrontiers in Pharmacology, 2019
Despite the tremendous progress made in the field of cancer therapy in recent years, certain solid tumors still cannot be successfully treated. Alongside classical treatments in the form of chemotherapy and/or radiotherapy, targeted treatments such as immunotherapy that cause fewer side effects emerge as new options in the clinics.
Mathie Najberg   +6 more
openaire   +5 more sources

Construction of Human Monocyte Derived Macrophages Armed with Oncolytic Viruses

open access: yesBio-Protocol, 2013
Macrophages are involved in many key physiological processes and complex responses such as inflammatory, immunological, infectious and neoplastic diseases.
Munitta Muthana   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy